17-ケトステロイド
WordNet
- a steroid containing a ketone group
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2015/05/07 12:20:51」(JST)
[Wiki en表示]
Steroid skeleton. Carbons 18 and above can be absent.
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A 17-ketosteroid is a steroid that has a ketone (C=O) functional group at the 17 position (in the upper right corner of most diagrams.)
Examples of 17-ketosteroids include:
- Androstenedione
- Androsterone
- Estrone
- Dehydroepiandrosterone
External links
- MedlinePlus Encyclopedia 003460
Steroid classification
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C17 |
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C18 |
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C19 |
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C21 |
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C23 |
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C24 |
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C27 |
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Functional group |
- 17-Ketosteroid
- Hydroxysteroid
- Halogenated steroid
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Elements removed |
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UpToDate Contents
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English Journal
- Influence of Occupational and Environmental Exposure to Low Concentrations of Polychlorobiphenyls and a Smoking Habit on the Urinary Excretion of Corticosteroid Hormones.
- D'Errico MN1, Lovreglio P2, Drago I3, Apostoli P4, Soleo L5.
- International journal of environmental research and public health.Int J Environ Res Public Health.2016 Mar 25;13(4). pii: E360. doi: 10.3390/ijerph13040360.
- The effects of occupational exposure to low concentrations of polychlorobiphenyls (PCBs) on the urinary excretion of corticosteroid hormones were evaluated, taking into account the influence of cigarette smoking. The study included 26 males working as electrical maintenance staff in a steel factory,
- PMID 27023579
- Mass spectrometry methods measured androgen and estrogen concentrations during pregnancy and in newborns of mothers with polycystic ovary syndrome.
- Caanen MR1, Kuijper EA2, Hompes PG2, Kushnir MM3, Rockwood AL3, Meikle WA3, Homburg R2, Lambalk CB2.
- European journal of endocrinology / European Federation of Endocrine Societies.Eur J Endocrinol.2016 Jan;174(1):25-32. doi: 10.1530/EJE-15-0699.
- OBJECTIVE: Little is known about the aetiology of polycystic ovary syndrome (PCOS). Some suggest that elevated maternal androgens during gestation play a causative role. This implies placental passage of androgens during pregnancy. The aim of this study is to compare androgen and estrogen concentrat
- PMID 26586837
- Synthesis of Denosomin-Vitamin D3 Hybrids and Evaluation of Their Anti-Alzheimer's Disease Activities.
- Sugimoto K1, Yajima H1, Hayashi Y1, Minato D1, Terasaki S1, Tohda C1, Matsuya Y1.
- Organic letters.Org Lett.2015 Dec 4;17(23):5910-3. doi: 10.1021/acs.orglett.5b03138. Epub 2015 Nov 20.
- As an extension of previously conducted studies on developing an anti-Alzheimer's disease agent, denosomin (1-deoxy-24-norsominone, an artificial inducer of neurite elongation), derivatives were designed and synthesized based on the hypothesis that our denosomin would exhibit axonal extension activi
- PMID 26588585
Japanese Journal
- 尿中17-ケトステロイド(17-KS)とその分画 (広範囲 血液・尿化学検査 免疫学的検査(第7版・4)その数値をどう読むか) -- (内分泌学的検査 副腎皮質関係)
- 呼吸調節下の軽強度運動時心拍変動スペクトルと尿中副腎ホルモンからみた自律神経機能の変化
- 永田 晟,田島 多恵子
- 日本運動生理学雑誌 13(2), 55-62, 2006-09-30
- … HRV spectra, the catecholamine (CA), 17-Ketosteroids (17-KS-S), and 17- Hydroxy corticoids (17-OHCS) of the adrenal hormone in the urine were measured during three experiments of these regulation of RR. …
- NAID 110004848694
Related Links
- 17-ketosteroids are substances that form when the body breaks down male steroid sex hormones called androgens and other hormones released by the adrenal glands in males and females, and by the testes in males.
- Free reference information from The NY Times on medical tests, normal results, abnormal results and diagnosis, as well as links to related news and features. ... 17-ketosteroids are substances that form when the body breaks down ...
Related Pictures
★リンクテーブル★
[★]
- 英
- 17-ketosteroids, (国試)17-KS
- 同
- 17-オキソステロイド 17-oxosteroid
- 関
- チンマーマン反応、尿中17-ケトステロイド、17-ヒドロキシコルチコステロイド
概念
尿中17-ケトステロイド
- コルチゾール、もしくはアンドロゲンが代謝されてできる物質の総称。
意義
- クッシング病、異所性ACTH症候群では増加、副腎癌では著増するが、副腎腺腫・副腎皮質結節性過形成では正常~低下する。 ← 後者2つでは、副腎アンドロゲンの産生が亢進していないということか??血清DHEA-Sでもやや同じ挙動がみられるし。
由来
- 副腎由来:2/3~3/4
- 精巣由来:1/4~1/3