UpToDate Contents

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

1. 巨核球の生物学と血小板の産生megakaryocyte biology and the production of platelets [show details]
… suggested that the morphologic findings might be related to ineffective platelet production . Electron microscopic examination of bone marrow from ITP patients shows that many megakaryocytes are undergoing …
2. 小児における赤血球産生低下による貧血原因の概要overview of causes of anemia in children due to decreased red blood cell production [show details]
…cardiopulmonary disease or exposure to high altitude), stimulate EPO production and thus RBC production. Metabolic factors may influence EPO production. For example, hypothyroidism, starvation, and hypophysectomy …
3. 好中球二次顆粒欠損症neutrophil specific granule deficiency [show details]
…myeloid-specific transcription factor, CCAAT/enhancer-binding protein epsilon (CEBPE) . A five-base pair frameshift deletion in the second exon of CEBPE identified in one patient resulted in a truncated … SGD were found to have decreased levels of the monocyte-specific enzyme, nonspecific esterase, and electron-microscopic examination revealed morphologic differences between SGD monocytes and normal controls … Interleukin (IL) 6 modulates acute phase reactants and enhances B cell antibody production,…
4. AAアミロイドーシスの発症機序pathogenesis of aa amyloidosis [show details]
… Acute phase SAA may directly stimulate the production of TNF-alpha and acute phase pentraxin production by synoviocytes ; SAA can mediate inflammatory… SAA2 has two alleles (alpha and beta) that differ from each other by a single base pair substitution at codon 71 resulting in an adenine substitution of guanine .… the glomeruli, while larger fragments may preferentially deposit in the blood vessels . Cryogenic electron microscopy (CryoEM) studies of AA amyloid fibrils purified from tissue compared with those formed…
5. 遺伝学の基礎概念：DNA制御と遺伝子発現basic genetics concepts dna regulation and gene expression [show details]
… 16,589 base pairs long and contains 37 genes, 13 of which are protein coding. Many of these are involved in mitochondrial respiration and the electron transport chain.… which suppresses the formation of female gonads (via production of anti-Mullerian hormone) and initiates development of male reproductive organs.…