心室型ミオシン
- 関
- alpha-myosin、beta-myosin、cardiac alpha-myosin、ventricular alpha-myosin、ventricular beta-myosin
WordNet
- of or relating to a ventricle (of the heart or brain)
- the commonest protein in muscle; a globulin that combines with actin to form actomyosin
UpToDate Contents
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- 1. 肥大型心筋症の遺伝学 genetics of hypertrophic cardiomyopathy
- 2. 肥大型心筋症の自然経過 natural history of hypertrophic cardiomyopathy
- 3. 心筋症の定義および分類 definition and classification of the cardiomyopathies
- 4. 心不全の病態生理：左心室の圧-容積関係 pathophysiology of heart failure left ventricular pressure volume relationships
- 5. 肥大型心筋症における心室性不整脈および突然の心停止 ventricular arrhythmias and sudden cardiac arrest in hypertrophic cardiomyopathy
English Journal
- Hypoxia activates muscle-restricted coiled-coil protein (MURC) expression via transforming growth factor-β in cardiac myocytes.
- Shyu KG, Cheng WP, Wang BW, Chang H.Source*Division of Cardiology, Shin Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan.
- Clinical science (London, England : 1979).Clin Sci (Lond).2014 Mar 1;126(5):367-75. doi: 10.1042/CS20130260.
- The expression of MURC (muscle-restricted coiled-coil protein), a hypertrophy-regulated gene, increases during pressure overload. Hypoxia can cause myocardial hypertrophy; however, how hypoxia affects the regulation of MURC in cardiomyocytes undergoing hypertrophy is still unknown. The aim of the pr
- PMID 24001173
- Increase in cardiac myosin heavy-chain (MyHC) alpha protein isoform in hibernating ground squirrels, with echocardiographic visualization of ventricular wall hypertrophy and prolonged contraction.
- Nelson OL, Rourke BC.SourceCollege of Veterinary Medicine, Washington State University, Pullman, WA 99164, USA.
- The Journal of experimental biology.J Exp Biol.2013 Dec 15;216(Pt 24):4678-90. doi: 10.1242/jeb.088773. Epub 2013 Sep 26.
- Deep hibernators such as golden-mantled ground squirrels (Callospermophilus lateralis) have multiple challenges to cardiac function during low temperature torpor and subsequent arousals. As heart rates fall from over 300 beats min(-1) to less than 10, chamber dilation and reduced cardiac output coul
- PMID 24072796
- Familial ebstein anomaly, left ventricular hypertrabeculation, and ventricular septal defect associated with a MYH7 mutation.
- Bettinelli AL, Mulder TJ, Funke BH, Lafferty KA, Longo SA, Niyazov DM.SourceMedical Genetics Department, Ochsner Clinic Foundation, New Orleans, Louisiana.
- American journal of medical genetics. Part A.Am J Med Genet A.2013 Dec;161(12):3187-90. doi: 10.1002/ajmg.a.36182. Epub 2013 Aug 16.
- Ebstein anomaly is a rare congenital heart defect that most often occurs sporadically within a kindred. Familial cases, although reported, are uncommon. At this time, the genetic etiology of Ebstein anomaly is not fully elucidated. Here, we describe clinical and molecular investigations of a rare ca
- PMID 23956225
Japanese Journal
- Dilated Phase of Hypertrophic Cardiomyopathy Caused by Two Different Sarcomere Mutations, Treated with Surgical Left Ventricular Reconstruction and Cardiac Resynchronization Therapy with a Defibrillator
- Sato Akihiko,Sakamoto Nobuo,Ando Katsuya,Kaneshiro Takashi,Uekita Hironori,Sugimoto Koichi,Yamaki Takayoshi,Kunii Hiroyuki,Nakazato Kazuhiko,Suzuki Hitoshi,Saitoh Shu-ichi,Sato Masatomo,Tamagawa Kazuaki,Arimura Takuro,Kimura Akinori,Takeishi Yasuchika
- Internal Medicine 51(18), 2559-2564, 2012
- … On admission, her left ventricle (LV) had marked dilation, dyssynchrony with diffuse severe hypokinesis, and ventricular tachycardia. … She had two mutations in the cardiac myosin binding protein-C gene, which were suspected to be the causes of the D-HCM. …
- NAID 130002062381
- Genetic Screening and Double Mutation in Japanese Patients With Hypertrophic Cardiomyopathy
- KUBO Toru,KITAOKA Hiroaki,OKAWA Makoto,BABA Yuichi,HIROTA Takayoshi,HAYATO Kayo,YAMASAKI Naohito,MATSUMURA Yoshihisa,OTSUKA Haruna,ARIMURA Takuro,KIMURA Akinori,DOI Yoshinori L.
- Circulation journal : official journal of the Japanese Circulation Society 75(11), 2654-2659, 2011-10-25
- … biMethods and Results:/i/b A comprehensive genetic analysis of 5 sarcomere genes (cardiac β-myosin heavy chain gene [iMYH7/i], cardiac myosin-binding protein C gene [iMYBPC3/i], cardiac troponin T gene [iTNNT2/i], α-tropomyosin gene [iTPM1/i] and cardiac troponin I gene [iTNNI3/i]) was performed in 93 unrelated patients and 14 mutations were identified in 28 patients. …
- NAID 10030032426
- Long-Term Treatment With Eicosapentaenoic Acid Ameliorates Myocardial Ischemia-Reperfusion Injury in Pigs In Vivo : Involvement of Rho-Kinase Pathway Inhibition
- GAO Jun Yi,YASUDA Satoshi,TSUBURAYA Ryuji,ITO Yoshitaka,SHIROTO Takashi,HAO Kiyotaka,AIZAWA Kentaro,KIKUCHI Yoku,ITO Kenta,SHIMOKAWA Hiroaki
- Circulation journal : official journal of the Japanese Circulation Society 75(8), 1843-1851, 2011-07-25
- … The EPA treatment significantly ameliorated myocardial I/R injury, including regional wall motion abnormality (EPA 5.3±3.6 vs. control 35.1±3.8 unit, P0.0001), left ventricular ejection fraction (EPA 43±9% vs. control 32±7%, P0.05), occurrence of ventricular arrhythmias (EPA 181±73 vs. control 389±51 events, P0.0001) and histological accumulation of inflammatory cells (P0.01). …
- NAID 10029127641
Related Links
- Recent gene knock-out studies in mice have suggested that ventricular myosin light chain-2 (vMLC2) has a role in the regulation of cardiogenic development and that perturbation in expression of vMLC2 is linked to the onset of dilated ...
- Dev Dyn. 2009 Jul;238(7):1760-7. doi: 10.1002/dvdy.22000. Promoter analysis of ventricular myosin heavy chain (vmhc) in zebrafish embryos. Jin D, Ni TT, Hou J, Rellinger E, Zhong TP. The Key Laboratory of Molecular Medicine, Shanghai ...
★リンクテーブル★
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βミオシン
- 関
- alpha-myosin、cardiac alpha-myosin、ventricular alpha-myosin、ventricular beta-myosin、ventricular myosin
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αミオシン
- 関
- beta-myosin、cardiac alpha-myosin、ventricular alpha-myosin、ventricular beta-myosin、ventricular myosin
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心筋αミオシン
- 関
- alpha-myosin、beta-myosin、ventricular alpha-myosin、ventricular beta-myosin、ventricular myosin
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心筋βミオシン
- 関
- alpha-myosin、beta-myosin、cardiac alpha-myosin、ventricular alpha-myosin、ventricular myosin
[★]
心筋αミオシン
- 関
- alpha-myosin、beta-myosin、cardiac alpha-myosin、ventricular beta-myosin、ventricular myosin
[★]
- 関
- cardiac ventricle、cerebral ventricle、cerebroventricle、cerebroventricular、heart ventricle、ventricle、ventriculi、ventriculus