ventricular myosin

出典: meddic


alpha-myosinbeta-myosincardiac alpha-myosinventricular alpha-myosinventricular beta-myosin

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  • Hypoxia activates muscle-restricted coiled-coil protein (MURC) expression via transforming growth factor-β in cardiac myocytes.
  • Shyu KG, Cheng WP, Wang BW, Chang H.Source*Division of Cardiology, Shin Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan.
  • Clinical science (London, England : 1979).Clin Sci (Lond).2014 Mar 1;126(5):367-75. doi: 10.1042/CS20130260.
  • The expression of MURC (muscle-restricted coiled-coil protein), a hypertrophy-regulated gene, increases during pressure overload. Hypoxia can cause myocardial hypertrophy; however, how hypoxia affects the regulation of MURC in cardiomyocytes undergoing hypertrophy is still unknown. The aim of the pr
  • PMID 24001173
  • Increase in cardiac myosin heavy-chain (MyHC) alpha protein isoform in hibernating ground squirrels, with echocardiographic visualization of ventricular wall hypertrophy and prolonged contraction.
  • Nelson OL, Rourke BC.SourceCollege of Veterinary Medicine, Washington State University, Pullman, WA 99164, USA.
  • The Journal of experimental biology.J Exp Biol.2013 Dec 15;216(Pt 24):4678-90. doi: 10.1242/jeb.088773. Epub 2013 Sep 26.
  • Deep hibernators such as golden-mantled ground squirrels (Callospermophilus lateralis) have multiple challenges to cardiac function during low temperature torpor and subsequent arousals. As heart rates fall from over 300 beats min(-1) to less than 10, chamber dilation and reduced cardiac output coul
  • PMID 24072796
  • Familial ebstein anomaly, left ventricular hypertrabeculation, and ventricular septal defect associated with a MYH7 mutation.
  • Bettinelli AL, Mulder TJ, Funke BH, Lafferty KA, Longo SA, Niyazov DM.SourceMedical Genetics Department, Ochsner Clinic Foundation, New Orleans, Louisiana.
  • American journal of medical genetics. Part A.Am J Med Genet A.2013 Dec;161(12):3187-90. doi: 10.1002/ajmg.a.36182. Epub 2013 Aug 16.
  • Ebstein anomaly is a rare congenital heart defect that most often occurs sporadically within a kindred. Familial cases, although reported, are uncommon. At this time, the genetic etiology of Ebstein anomaly is not fully elucidated. Here, we describe clinical and molecular investigations of a rare ca
  • PMID 23956225


  • Dilated Phase of Hypertrophic Cardiomyopathy Caused by Two Different Sarcomere Mutations, Treated with Surgical Left Ventricular Reconstruction and Cardiac Resynchronization Therapy with a Defibrillator
  • Sato Akihiko,Sakamoto Nobuo,Ando Katsuya,Kaneshiro Takashi,Uekita Hironori,Sugimoto Koichi,Yamaki Takayoshi,Kunii Hiroyuki,Nakazato Kazuhiko,Suzuki Hitoshi,Saitoh Shu-ichi,Sato Masatomo,Tamagawa Kazuaki,Arimura Takuro,Kimura Akinori,Takeishi Yasuchika
  • Internal Medicine 51(18), 2559-2564, 2012
  • … On admission, her left ventricle (LV) had marked dilation, dyssynchrony with diffuse severe hypokinesis, and ventricular tachycardia. … She had two mutations in the cardiac myosin binding protein-C gene, which were suspected to be the causes of the D-HCM. …
  • NAID 130002062381
  • Genetic Screening and Double Mutation in Japanese Patients With Hypertrophic Cardiomyopathy
  • KUBO Toru,KITAOKA Hiroaki,OKAWA Makoto,BABA Yuichi,HIROTA Takayoshi,HAYATO Kayo,YAMASAKI Naohito,MATSUMURA Yoshihisa,OTSUKA Haruna,ARIMURA Takuro,KIMURA Akinori,DOI Yoshinori L.
  • Circulation journal : official journal of the Japanese Circulation Society 75(11), 2654-2659, 2011-10-25
  • … biMethods and Results:/i/b A comprehensive genetic analysis of 5 sarcomere genes (cardiac β-myosin heavy chain gene [iMYH7/i], cardiac myosin-binding protein C gene [iMYBPC3/i], cardiac troponin T gene [iTNNT2/i], α-tropomyosin gene [iTPM1/i] and cardiac troponin I gene [iTNNI3/i]) was performed in 93 unrelated patients and 14 mutations were identified in 28 patients. …
  • NAID 10030032426
  • Long-Term Treatment With Eicosapentaenoic Acid Ameliorates Myocardial Ischemia-Reperfusion Injury in Pigs In Vivo : Involvement of Rho-Kinase Pathway Inhibition
  • GAO Jun Yi,YASUDA Satoshi,TSUBURAYA Ryuji,ITO Yoshitaka,SHIROTO Takashi,HAO Kiyotaka,AIZAWA Kentaro,KIKUCHI Yoku,ITO Kenta,SHIMOKAWA Hiroaki
  • Circulation journal : official journal of the Japanese Circulation Society 75(8), 1843-1851, 2011-07-25
  • … The EPA treatment significantly ameliorated myocardial I/R injury, including regional wall motion abnormality (EPA 5.3±3.6 vs. control 35.1±3.8 unit, P0.0001), left ventricular ejection fraction (EPA 43±9% vs. control 32±7%, P0.05), occurrence of ventricular arrhythmias (EPA 181±73 vs. control 389±51 events, P0.0001) and histological accumulation of inflammatory cells (P0.01). …
  • NAID 10029127641


Recent gene knock-out studies in mice have suggested that ventricular myosin light chain-2 (vMLC2) has a role in the regulation of cardiogenic development and that perturbation in expression of vMLC2 is linked to the onset of dilated ...
Dev Dyn. 2009 Jul;238(7):1760-7. doi: 10.1002/dvdy.22000. Promoter analysis of ventricular myosin heavy chain (vmhc) in zebrafish embryos. Jin D, Ni TT, Hou J, Rellinger E, Zhong TP. The Key Laboratory of Molecular Medicine, Shanghai ...


 Ventricular Myosin Heavy Chain (vmhc of Ventricular Ejection and RelaxationSliding Filament Myosin Heads Move Towards of the left ventricular myosin Cardiac Myosin-Binding Protein C Is Consequences of Mutations in the Myosin

リンク元beta-myosin」「alpha-myosin」「cardiac alpha-myosin」「ventricular alpha-myosin」「ventricular beta-myosin




alpha-myosincardiac alpha-myosinventricular alpha-myosinventricular beta-myosinventricular myosin




beta-myosincardiac alpha-myosinventricular alpha-myosinventricular beta-myosinventricular myosin

cardiac alpha-myosin」



alpha-myosinbeta-myosinventricular alpha-myosinventricular beta-myosinventricular myosin

ventricular alpha-myosin」



alpha-myosinbeta-myosincardiac alpha-myosinventricular beta-myosinventricular myosin

ventricular beta-myosin」



alpha-myosinbeta-myosincardiac alpha-myosinventricular alpha-myosinventricular myosin



  • adj.
  • 室の、心室の、脳室の、心室性の
cardiac ventriclecerebral ventriclecerebroventriclecerebroventricularheart ventricleventricleventriculiventriculus

WordNet   license wordnet

「of or relating to a ventricle (of the heart or brain)」


  [★] ミオシン

WordNet   license wordnet

「the commonest protein in muscle; a globulin that combines with actin to form actomyosin」