関: alpha-myosin、beta-myosin、cardiac alpha-myosin、ventricular beta-myosin、ventricular myosin

WordNet

first in order of importance; "the alpha male in the group of chimpanzees"; "the alpha star in a constellation is the brightest or main star"
the 1st letter of the Greek alphabet
the beginning of a series or sequence; "the Alpha and Omega, the first and the last, the beginning and the end"--Revelations
early testing stage of a software or hardware product; "alpha version"
of or relating to a ventricle (of the heart or brain)
any high mountain
the commonest protein in muscle; a globulin that combines with actin to form actomyosin

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Ensemble Force Changes that Result from Human Cardiac Myosin Mutations and a Small-Molecule Effector.

Aksel T1, Choe Yu E2, Sutton S1, Ruppel KM3, Spudich JA4.
Cell reports.Cell Rep.2015 May 12;11(6):910-20. doi: 10.1016/j.celrep.2015.04.006. Epub 2015 Apr 30.
Cardiomyopathies due to mutations in human β-cardiac myosin are a significant cause of heart failure, sudden death, and arrhythmia. To understand the underlying molecular basis of changes in the contractile system's force production due to such mutations and search for potential drugs that restore
PMID 25937279

HDAC inhibition attenuates cardiac hypertrophy by acetylation and deacetylation of target genes.

Ooi JY1, Tuano NK, Rafehi H, Gao XM, Ziemann M, Du XJ, El-Osta A.
Epigenetics : official journal of the DNA Methylation Society.Epigenetics.2015 May 4;10(5):418-30. doi: 10.1080/15592294.2015.1024406. Epub 2015 May 5.
Pharmacological histone deacetylase (HDAC) inhibitors attenuate pathological cardiac remodeling and hypertrophic gene expression; yet, the direct histone targets remain poorly characterized. Since the inhibition of HDAC activity is associated with suppressing hypertrophy, we hypothesized histone ace
PMID 25941940

l-Arginine Attenuates Cardiac Dysfunction, But Further Down-Regulates α-Myosin Heavy Chain Expression in Isoproterenol-Induced Cardiomyopathy.

Kralova E1, Doka G, Pivackova L, Srankova J, Kuracinova K, Janega P, Babal P, Klimas J, Krenek P.
Basic & clinical pharmacology & toxicology.Basic Clin Pharmacol Toxicol.2015 Apr 10. doi: 10.1111/bcpt.12405. [Epub ahead of print]
In view of previously reported increased capacity for nitric oxide production, we suggested that l-arginine (ARG), the nitric oxide synthase (NOS) substrate, supplementation would improve cardiac function in isoproterenol (ISO)-induced heart failure. Male Wistar rats were treated with ISO for 8 day
PMID 25865156

リンク元	「心筋αミオシン」「beta-myosin」「ventricular myosin」「alpha-myosin」「cardiac alpha-myosin」
関連記事	「ventricular」「alpha」