vascular-endothelial growth factor

出典: meddic

血管内皮増殖因子 VEGF

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英文文献

  • Quantification of the vascular endothelial growth factor with a bioluminescence resonance energy transfer (BRET) based single molecule biosensor.
  • Wimmer T1, Lorenz B1, Stieger K2.
  • Biosensors & bioelectronics.Biosens Bioelectron.2016 Dec 15;86:609-15. doi: 10.1016/j.bios.2016.07.058. Epub 2016 Jul 19.
  • Neovascular pathologies in the eye like age-related macular degeneration (AMD), the diabetic retinopathie (DR), retinopathie of prematurity (ROP) or the retinal vein occlusion (RVO) are caused through a hypoxia induced upregulation of the vascular endothelial growth factor (VEGF). So far a correlati
  • PMID 27459244
  • Nailfold videocapillaroscopy and serum VEGF levels in scleroderma are associated with internal organ involvement.
  • De Santis M1, Ceribelli A1,2, Cavaciocchi F1, Crotti C1, Massarotti M1, Belloli L1,3, Marasini B1, Isailovic N1, Generali E1, Selmi C4,5.
  • Auto- immunity highlights.Auto Immun Highlights.2016 Dec;7(1):5. doi: 10.1007/s13317-016-0077-y. Epub 2016 Feb 15.
  • PURPOSE: Nailfold videocapillaroscopy (NVC) identifies the microvascular hallmarks of systemic sclerosis (SSc) and vascular endothelial growth factor (VEGF) and may play a pivotal role in the associated vasculopathy. The aim of the present study was to compare NVC alterations with clinical subsets,
  • PMID 26878864
  • Targeted scVEGF/(177)Lu radiopharmaceutical inhibits growth of metastases and can be effectively combined with chemotherapy.
  • Rusckowski M1, Wang Y, Blankenberg FG2, Levashova Z2,3, Backer MV4, Backer JM5.
  • EJNMMI research.EJNMMI Res.2016 Dec;6(1):4. doi: 10.1186/s13550-016-0163-1. Epub 2016 Jan 16.
  • BACKGROUND: scVEGF/(177)Lu is a novel radiopharmaceutical targeted by recombinant single-chain (sc) derivative of vascular endothelial growth factor (VEGF) that binds to and is internalized by vascular endothelial growth factor receptors (VEGFR). scVEGF/(177)Lu potential as adjuvant and neoadjuvant
  • PMID 26780081

和文文献

  • Promotion Effect of Apo-9'-fucoxanthinone from Sargassum muticum on Hair Growth via the Activation of Wnt/β-Catenin and VEGF-R2
  • Biological & pharmaceutical bulletin 39(8), 1273-1283, 2016-08
  • NAID 40020899503
  • Effect of Vandetanib on Lung Tumorigenesis in Transgenic Mice Carrying an Activating Egfr Gene Mutation
  • 腎がんに対するmTOR/PI3K阻害剤とVEGFシグナル阻害剤など (特集 分子治療薬を用いた併用療法の理論と効果)

関連リンク

This gene is a member of the PDGF/VEGF growth factor family. It encodes a heparin-binding protein, which exists as a disulfide-linked homodimer. This growth factor induces proliferation and migration of vascular endothelial cells, and ...
1. Endocr Rev. 2004 Aug;25(4):581-611. Vascular endothelial growth factor: basic science and clinical progress. Ferrara N(1). Author information: (1)Department of Molecular Oncology, Genentech, Inc., 1 DNA Way, South ...

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★リンクテーブル★
先読み血管内皮増殖因子」「VEGF
関連記事grow」「growth」「factor」「fact」「vascular

血管内皮増殖因子」

  [★]

vascular endothelial growth factor, VEGF
血管内皮細胞増殖因子vascular endothelial cell growth factor
血管新生
[show details]


  • 癌における血管新生に関与している (同:VEGF。対:angiostatin, endostatin, vasculostatin)
  • 標的は血管内皮細胞のみ
  • 腫瘍や心臓や網膜の虚血部位で過剰に産生される。
  • 低酸素状態にさらされた組織で過剰に産生される。



VEGF」

  [★] 血管内皮増殖因子 vascular endothelial growth factor


grow」

  [★]

  • v.
(過去: grew-過去分詞: grown)
extendgrowthoutgrowoutgrowthstretch

WordNet   license wordnet

「cultivate by growing, often involving improvements by means of agricultural techniques; "The Bordeaux region produces great red wines"; "They produce good ham in Parma"; "We grow wheat here"; "We raise hogs here"」
raise, farm, produce

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「come to have or undergo a change of (physical features and attributes); "He grew a beard"; "The patient developed abdominal pains"; "I got funny spots all over my body"; "Well-developed breasts"」
develop, produce, get, acquire

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「become attached by or as if by the process of growth; "The tree trunks had grown together"」

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「become larger, greater, or bigger; expand or gain; "The problem grew too large for me"; "Her business grew fast"」

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「cause to grow or develop; "He grows vegetables in his backyard"」

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「increase in size by natural process; "Corn doesn''t grow here"; "In these forests, mushrooms grow under the trees"; "her hair doesn''t grow much anymore"」

PrepTutorEJDIC   license prepejdic

「『成長する』,育つ,〈植物が〉生える,茂る / (類・量・程などにおいて)『増大する』,大きくなる / 『しだいになる』 / …‘を'成長させる,大きくする,育てる / …から生じる(起こる)」

growth」

  [★]

  • n.
  • 成長


WordNet   license wordnet

「(biology) the process of an individual organism growing organically; a purely biological unfolding of events involved in an organism changing gradually from a simple to a more complex level; "he proposed an indicator of osseous development in children"」
growing, maturation, development, ontogeny, ontogenesis

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「(pathology) an abnormal proliferation of tissue (as in a tumor)」

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「a progression from simpler to more complex forms; "the growth of culture"」

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「something grown or growing; "a growth of hair"」

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「vegetation that has grown; "a growth of trees"; "the only growth was some salt grass"」

PrepTutorEJDIC   license prepejdic

「〈U〉(…の)『成長』,発育;『発達』,発展《+『of』+『名』》 / 〈U〉(数・量,重要性・力などの)『増加』,増大,拡張《+『of』+『名』》 / 〈U〉《修飾語[句]を伴って》栽培,生産,…産 / 〈C〉成育した物,(草,木,髪,ひげなどの)生えたもの / 〈C〉腫瘍(しゅよう)」


factor」

  [★]

  • n.
elementelementaryfactorialparameter

WordNet   license wordnet

「be a contributing factor; "make things factor into a company''s profitability"」

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「any of the numbers (or symbols) that form a product when multiplied together」

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「an independent variable in statistics」

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「anything that contributes causally to a result; "a number of factors determined the outcome"」

PrepTutorEJDIC   license prepejdic

「(…の)『要因』,(…を生み出す)要素《+『in』+『名』(do『ing』)》 / 囲数,約数 / 代理人,《おもに英》仲買人 / =factorize」

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「consider as relevant when making a decision; "You must factor in the recent developments"」
factor in, factor out

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「resolve into factors; "a quantum computer can factor the number 15"」
factor in, factor out


fact」

  [★]

  • n.
actualactuallyin factin practiceindeedpractically

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「an event known to have happened or something known to have existed; "your fears have no basis in fact"; "how much of the story is fact and how much fiction is hard to tell"」

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「a concept whose truth can be proved; "scientific hypotheses are not facts"」

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「a piece of information about circumstances that exist or events that have occurred; "first you must collect all the facts of the case"」

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「a statement or assertion of verified information about something that is the case or has happened; "he supported his argument with an impressive array of facts"」

PrepTutorEJDIC   license prepejdic

「〈C〉『事実』,実際にある(あった)事 / 〈U〉真相,真実(truth) / 《the~》(法律用語で)犯行」

vascular」

  [★]

  • adj.
  • (生物・解剖)導管の、脈管の、血管の
angioblood vesselfibrovascular bundlevascular bundlevasculogenicveinvessel

WordNet   license wordnet

「of or relating to or having vessels that conduct and circulate fluids; "vascular constriction"; "a vascular bundle"」

PrepTutorEJDIC   license prepejdic

「(血液・樹液などを運ぶ)管の,導管の,血管の」




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