site-specific DNA methyltransferase

部位特異的DNAメチル化酵素、部位特異的DNAメチル基転移酵素

WordNet

1. serve in a specific professional capacity; "the priest sat for confession"; "she sat on the jury"
2. be around, often idly or without specific purpose; "The object sat in the corner"; "We sat around chatting for another hour" (同)sit around
3. be seated (同)sit_down
4. be in session; "When does the court of law sit?"
5. be located or situated somewhere; "The White House sits on Pennsylvania Avenue"
6. stated explicitly or in detail; "needed a specific amount"
7. a medicine that has a mitigating effect on a specific disease; "quinine is a specific for malaria"
8. (sometimes followed by `to'
9. being or affecting a disease produced by a particular microorganism or condition; used also of stains or dyes used in making microscope slides; "quinine is highly specific for malaria"; "a specific remedy"; "a specific stain is one having a specific affinity for particular structural elements"
10. relating to or distinguishing or constituting a taxonomic species; "specific characters"
11. the piece of land on which something is located (or is to be located); "a good site for the school" (同)land site
12. physical position in relation to the surroundings; "the sites are determined by highly specific sequences of nucleotides" (同)situation
13. the 4th letter of the Roman alphabet (同)d

PrepTutorEJDIC

1. (…に)『座る』,座っている《+『at』(『on, in』)+『名』》・着席する《+『down』》・(…に)〈鳥などが〉『止まる』,休む《+『on』+『名』》・〈めんどりが〉卵を抱く,巣に就く / 《場所の副詞[句]を伴って》(ある場所に)『位置する』・ (画家・写真家のために)ポーズをとる・しっとしている,動かないでいる・(議員・委員などの)職に就いている《+『on』+『名』》・〈議会・法廷などが〉開会(開廷)される・(…に)負担となる,重荷となる《+『on』(『upon』)+『名』》・〈衣服などが〉(…に)合う,似合う《+『on』+『名』》・〈人〉‘を'座らせる,着席させる《+『down』+『名,』+『名』+『down』》・〈馬〉‘に'乗る・《英》〈試験〉‘を'受ける
2. 《名詞の前にのみ用いて》『特定の』,一定の・『明確な』,明白な・(そのものに)『特有の』,独特の《+『to』+『名』》・〈C〉(…の)特効薬《+『for』+『名』》・《複数形で》明細,細部(details)
3. (町・建物などの)『場所』;敷地,用地 / 遺跡;(事件などの)現場 / 〈建物など〉‘を'位置させる(locate)
4. deuteriumの化学記号
5. deoxyribonucleic acidディオキシリボ核酸

UpToDate Contents

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• 4. 次世代DNAシークエンシングの原理および臨床応用 principles and clinical applications of next generation dna sequencing
• 5. サイトメガロウイルス感染の診断へのアプローチ approach to the diagnosis of cytomegalovirus infection

English Journal

• Bacterial Autoimmunity Due to a Restriction-Modification System.

• Pleška M1, Qian L2, Okura R3, Bergmiller T1, Wakamoto Y4, Kussell E5, Guet CC6.
• Current biology : CB.Curr Biol.2016 Jan 19. pii: S0960-9822(15)01572-9. doi: 10.1016/j.cub.2015.12.041. [Epub ahead of print]
• Restriction-modification (RM) systems represent a minimal and ubiquitous biological system of self/non-self discrimination in prokaryotes [1], which protects hosts from exogenous DNA [2]. The mechanism is based on the balance between methyltransferase (M) and cognate restriction endonuclease (R). M
• PMID 26804559

• Structural optimization of non-nucleoside DNA methyltransferase inhibitor as anti-cancer agent.

• Zhong B1, Vatolin S2, Idippily ND1, Lama R1, Alhadad LA1, Reu FJ3, Su B4.
• Bioorganic & medicinal chemistry letters.Bioorg Med Chem Lett.2016 Jan 9. pii: S0960-894X(16)30020-8. doi: 10.1016/j.bmcl.2016.01.020. [Epub ahead of print]
• Inhibition of DNA methyltransferase 1 (DNMT1) can reverse the malignant behavior of cancer cells by restoring expression of aberrantly silenced genes that are required for differentiation, senescence, and apoptosis. Clinically used DNMT1 inhibitors decitabine and azacitidine inhibit their target by
• PMID 26774653

• Detection of DNA methyltransferase activity using allosteric molecular beacons.

• Zhang W1, Zu X1, Song Y1, Zhu Z1, Yang CJ1.
• The Analyst.Analyst.2016 Jan 4;141(2):579-84. doi: 10.1039/c5an01763g.
• Abnormal DNA methylation patterns caused by altered DNA methyltransferase (MTase) activity are closely associated with cancer. Herein, using DNA adenine methylation methyltransferase (Dam MTase) as a model analyte, we designed an allosteric molecular beacon (aMB) for sensitive detection of Dam MTase
• PMID 26478921

Related Links

• GO:0009007 site-specific DNA-methyltransferase (adenine ...

The European Bioinformatics Institute ... Database Code Database Name UniProtKB Universal Protein Knowledgebase UniProtKB/Swiss-Prot UniProtKB/TrEMBL CGD Candida Genome Database dictyBase dictyBase

• PAB2246 - Site specific DNA-methyltransferase ...

Site specific DNA-methyltransferase Gene PAB2246 Organism Pyrococcus abyssi (strain GE5 / Orsay) Status Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predicted i Display All None Function ...

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★リンクテーブル★

リンク元	「部位特異的DNAメチル化酵素」「部位特異的DNAメチル基転移酵素」
関連記事	「specific」「sit」「D」「site」「DNA」

「部位特異的DNAメチル化酵素」

　　[★]

英

site-specific DNA methyltransferase

関

部位特異的DNAメチル基転移酵素

「部位特異的DNAメチル基転移酵素」

　　[★]

英

site-specific DNA methyltransferase

関

部位特異的DNAメチル化酵素

「specific」

　　[★]

• adj.

• (～に関して)明確な、はっきりとした(exact precise)、具体的な(in, about)
• (比較)(限定)特定の(particular)、一定の(⇔general)
• (～に)特有の、独特の(to)
• (比較)(医学)(～に)渡航のある(for)。特殊な
• (生物)(生物)種の
• 医学)特異の
• (物理)比の。物質固有の。単位質量・長さ・面積・容積で

n.

関

specifically、specificity

　 　 　 　 　 　

「sit」

　　[★]

• vi.

• (過去-過去分詞sat)座る、位置する

関

lie、locate、location、loci、locus、map、position、rank、seat、situated、situation、stand、topo

　 　 　 　 　 　

「D」

　　[★]

• アスパラギン酸
• ジヒドロウリジン
• 遠位の distal,
• うつ病 depression
• 下行結腸 descending colon(大腸内視鏡検査の結果を記載するときに用いる)

　 　

「site」

　　[★]

• n.

• 部位、場所、サイト

関

location、loci、locus、place、topo

　 　 　

「DNA」

　　[★]

英

deoxyribonucleic acid

同

デオキシリボ核酸

関

リボ核酸 RNA