selegiline

出典: meddic

セレギリン

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2015/12/07 21:50:25」(JST)

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英文文献

  • Comparison of two methods for selegiline determination: A flow-injection chemiluminescence method using cadmium sulfide quantum dots and corona discharge ion mobility spectrometry.
  • Khataee A1, Lotfi R2, Hasanzadeh A2, Iranifam M3, Zarei M4, Joo SW5.
  • Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy.Spectrochim Acta A Mol Biomol Spectrosc.2016 Jan 15;153:273-80. doi: 10.1016/j.saa.2015.08.036. Epub 2015 Aug 22.
  • Two analytical approaches including chemiluminescence (CL) and corona discharge ionization ion mobility spectrometry (CD-IMS) were developed for sensitive determination of selegiline (SG). We found that the CL intensity of the KMnO4-Na2S2O3 CL system was significantly enhanced in the presence of l-c
  • PMID 26318702
  • A systematic review and mixed treatment comparison of monotherapy in early Parkinson's disease: implications for Latin America.
  • Márquez-Cruz M1, Díaz-Martínez JP1, Soto-Molina H1, Jorge de Saráchaga A2, Cervantes-Arriaga A2, Llorens-Arenas R2,3, Rodríguez-Violante M2,3.
  • Expert review of pharmacoeconomics & outcomes research.Expert Rev Pharmacoecon Outcomes Res.2016 Jan 5. [Epub ahead of print]
  • Parkinson's disease (PD) is the second most common neurodegenerative disease. There are no clinical trials comparing all available pharmacological therapies for the treatment of early PD. The objective of this review is to indirectly analyze the efficacy of antiparkinson drugs currently available in
  • PMID 26731410
  • Freezing of Gait in Parkinsonism and its Potential Drug Treatment.
  • Zhang LL, Canning D, Wang XP1.
  • Current neuropharmacology.Curr Neuropharmacol.2015 Dec 1. [Epub ahead of print]
  • Freezing of gait is a heterogeneous symptom. Studies of treatment for FOG are scarce. Levodopa and monoamine oxidase inhibitors (rasagiline and selegiline) have shown effective improvement for FOG.Other drugs, such as L-threo- 3,4 -dihydroxyphenylserine, amantadine, and botulinum toxin have demonstr
  • PMID 26635194

和文文献

  • Dyskinesia-hyperpyrexia syndromeを合併したパーキンソン病の1例
  • Monitoring of Blood L-DOPA and L-DOPA Metabolite Concentrations and Adverse Events in Patients with Advanced Parkinson's Disease Receiving L-DOPA and MAO Inhibitor Selegiline ((-)Deprenyl) Combination Therapy : A Clinical Study
  • Zonisamide Attenuates MPTP Neurotoxicity in Marmosets
  • Journal of pharmacological sciences 114(3), 298-303, 2010-11-20
  • NAID 10029890426

関連リンク

Selegiline may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away: dizziness lightheadedness fainting dry mouth nausea vomiting stomach pain difficulty swallowing heartburn
Selegiline official prescribing information for healthcare professionals. Includes: indications, dosage, adverse reactions, pharmacology and more. ... In all prospectively monitored clinical investigations, enrolling approximately 920 ...

関連画像

Selegiline2DCSD.svgSelegilineدواء سيليجلين Selegiline  Eldepryl (Selegiline) Online! Low Prices Health > Generic Eldepryl- SelegilineEnlarge Selegiline


★リンクテーブル★
リンク元パーキンソン病治療薬」「セレギリン」「L-deprenyl
拡張検索selegiline hydrochloride

パーキンソン病治療薬」

  [★]

antiparkinson agent, antiparkinsonism drug
パーキンソン病薬理学

ドパミン前駆体

ドパミン受容体作動薬

MAO-B阻害薬

ドパミン放出促進

中枢性抗コリン作用

ノルアドレナリン前駆体


セレギリン」

  [★]

selegiline
塩酸セレギリン selegiline hydrochloride
デプレニール deprenyl


特徴

構造

作用機序

薬理作用

  • B型モノアミン酸化酵素阻害作用
  • ドパミン再取り込み阻害作用

動態

適応

注意

禁忌

副作用

相互作用

添付文書

  • セレギリン塩酸塩錠2.5mg「マイラン」
[display]http://www.info.pmda.go.jp/go/pack/1169010F1058_1_03/1169010F1058_1_03?view=body



L-deprenyl」

  [★]

L-デプレニル

deprenylselegilineselegiline hydrochloride


selegiline hydrochloride」

  [★]

deprenylL-deprenylselegiline




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