原核生物・訳開始因子1

WordNet

be a contributing factor; "make things factor into a companys profitability"
any of the numbers (or symbols) that form a product when multiplied together
an independent variable in statistics
anything that contributes causally to a result; "a number of factors determined the outcome"
consider as relevant when making a decision; "You must factor in the recent developments" (同)factor in, factor out
resolve into factors; "a quantum computer can factor the number 15" (同)factor in, factor out
an event known to have happened or something known to have existed; "your fears have no basis in fact"; "how much of the story is fact and how much fiction is hard to tell"
a concept whose truth can be proved; "scientific hypotheses are not facts"
a piece of information about circumstances that exist or events that have occurred; "first you must collect all the facts of the case"
a statement or assertion of verified information about something that is the case or has happened; "he supported his argument with an impressive array of facts"
the act of starting something for the first time; introducing something new; "she looked forward to her initiation as an adult"; "the foundation of a new scientific society" (同)founding, foundation, institution, origination, creation, innovation, introduction, instauration
a formal entry into an organization or position or office; "his initiation into the club"; "he was ordered to report for induction into the army"; "he gave a speech as part of his installation into the hall of fame" (同)induction, installation
having cells that lack membrane-bound nuclei (同)procaryotic

PrepTutorEJDIC

(…の)『要因』,(…を生み出す)要素《+『in』+『名』(do『ing』)》 / 囲数,約数 / 代理人,《おもに英》仲買人 / =factorize
〈C〉『事実』,実際にある(あった)事 / 〈U〉真相,真実(truth) / 《the~》(法律用語で)犯行
〈U〉開始;創業 / 〈U〉入会,入門;〈C〉入会(入門)式 / 〈U〉手ほどき,伝授

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2013/06/10 18:20:30」(JST)

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Prokaryotic initiation factor-1 is a prokaryotic initiation factor.^[1]

IF1 associates with the 30S ribosomal subunit in the A site and prevents an aminoacyl-tRNA from entering. It modulates IF2 binding to the ribosome by increasing its affinity. It may also prevent the 50S subunit from binding, stopping the formation of the 70S subunit. It also contains a β-domain fold common for nucleic acid binding proteins.

References[edit]

^ Prokaryotic Initiation Factor-1 at the US National Library of Medicine Medical Subject Headings (MeSH)

UpToDate Contents

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English Journal

Recombinant translation initiation factor-1 of Wolbachia is an immunogenic excretory secretory protein that elicits Th2 mediated immune protection against Brugia malayi.

Nag JK, Shrivastava N, Gupta J, Misra-Bhattacharya S.SourceDivision of Parasitology, CSIR-Central Drug Research Institute, Lucknow, Uttar Pradesh, India.
Comparative immunology, microbiology and infectious diseases.Comp Immunol Microbiol Infect Dis.2013 Jan;36(1):25-38. doi: 10.1016/j.cimid.2012.09.004. Epub 2012 Oct 15.
Wolbachia, the intracellular alpha-proteobacteria are required for the development, fertility and survival of filarial parasites. Wolbachia Translation initiation factor-1 (Wol Tl IF-1) is one of the factors required for Wolbachia growth and viability. In the present study, we cloned, over expressed
PMID 23079772

Mutations in 16S rRNA that suppress cold-sensitive initiation factor 1 affect ribosomal subunit association.

Belotserkovsky JM, Dabbs ER, Isaksson LA.SourceDepartment of Genetics, Microbiology and Toxicology, Stockholm University, Stockholm, Sweden.
The FEBS journal.FEBS J.2011 Sep;278(18):3508-17. doi: 10.1111/j.1742-4658.2011.08272.x.
A mutation in the infA gene encoding initiation factor 1 (IF1) gives rise to a cold-sensitive phenotype. An Escherichia coli strain with this mutation was used as a tool to select for second-site suppressors that compensate for the cold sensitivity and map specifically to rRNA. Several suppressor mu
PMID 21791000

Suppression of a cold-sensitive mutant initiation factor 1 by alterations in the 23S rRNA maturation region.

Belotserkovsky JM, Isak GI, Isaksson LA.SourceDepartment of Genetics, Microbiology and Toxicology, Stockholm University, Stockholm, Sweden.
The FEBS journal.FEBS J.2011 May;278(10):1745-56. doi: 10.1111/j.1742-4658.2011.08099.x. Epub 2011 Apr 13.
Genetic selection has been used to isolate second-site suppressors of a defective cold-sensitive initiation factor I (IF1) R69L mutant of Escherichia coli. The suppressor mutants specifically map to a single rRNA operon on a plasmid in a strain with all chromosomal rRNA operons deleted. Here, we des
PMID 21418143