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Erythropoietin resistance contributes to anaemia in chronic heart failure and relates to aberrant JAK-STAT signal transduction.

Okonko DO, Marley SB, Anker SD, Poole-Wilson PA, Gordon MY.SourceClinical Cardiology, National Heart & Lung Institute, Imperial College, London, UK. Electronic address: obiokonko@aol.com.
International journal of cardiology.Int J Cardiol.2013 Apr 15;164(3):359-64. doi: 10.1016/j.ijcard.2011.07.045. Epub 2011 Aug 6.
BACKGROUND: Chronic heart failure (CHF) patients are frequently anaemic despite elevated endogenous erythropoietin (Epo) levels. We tested the hypothesis that this might be due to Epo resistance and investigated whether any defects apparent were due to Epo receptor (EpoR) downregulation and/or impai
PMID 21821297

Influence of counting methodology on erythrocyte ratios in the mouse micronucleus test.

Lebaron MJ, Schisler MR, Torous DK, Dertinger SD, Gollapudi BB.SourceThe Dow Chemical Company, Toxicology and Environmental Research and Consulting, Midland, Michigan.
Environmental and molecular mutagenesis.Environ Mol Mutagen.2013 Apr;54(3):222-8. doi: 10.1002/em.21754. Epub 2012 Dec 6.
The mammalian erythrocyte micronucleus test is widely used to investigate the potential interaction of a test substance with chromosomes or mitotic apparatus of replicating erythroblasts. In addition to the primary endpoint, micronucleated erythrocyte frequency, the proportion of immature erythrocyt
PMID 23224994

Excessive EDTA induces morphologic changes in bone marrow smears that mimic specific features of dysplasia.

Lee SH, van der Weyden C, Mayson E, Desai S.SourceDepartment of Haematology, St George Hospital, South Eastern Area Laboratory Services, Sydney, Australia.
International journal of laboratory hematology.Int J Lab Hematol.2013 Apr;35(2):163-9. doi: 10.1111/ijlh.12015. Epub 2012 Oct 13.
INTRODUCTION: The WHO 2008 guidelines recommend that bone marrow (BM) slides for the morphological assessment of dysplasia should be made from freshly obtained BM specimens, and that specimens exposed to anticoagulants for more than two hours are unsatisfactory. However, BM aspirates may be exposed
PMID 23062172

Recent advances in non-invasive prenatal DNA diagnosis through analysis of maternal blood

SEKIZAWA Akihiko,PURWOSUNU Yuditiya,MATSUOKA Ryu,KOIDE Keiko,OKAZAKI Shiho,FARINA Antonio,SAITO Hiroshi,OKAI Takashi
The Journal of obstetrics and gynaecology research 33(6), 747-764, 2007-12-01
NAID 10020001838