inositol 1,4,5-trisphosphate

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2013/04/19 10:42:19」(JST)

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  • 600ns pulse electric field-induced phosphatidylinositol4,5-bisphosphate depletion.
  • Tolstykh GP1, Beier HT2, Roth CC3, Thompson GL4, Ibey BL2.
  • Bioelectrochemistry (Amsterdam, Netherlands).Bioelectrochemistry.2014 Dec;100:80-7. doi: 10.1016/j.bioelechem.2014.01.006. Epub 2014 Jan 29.
  • The interaction between nsPEF-induced Ca(2+) release and nsPEF-induced phosphatidylinositol4,5-bisphosphate (PIP2) hydrolysis is not well understood. To better understand this interrelation we monitored intracellular calcium changes, in cells loaded with Calcium Green-1 AM, and generation of PIP2 hy
  • PMID 24530104
  • A new calmodulin-binding motif for inositol 1,4,5-trisphosphate 3-kinase regulation.
  • Franco-Echevarría E1, Baños-Sanz JI1, Monterroso B2, Round A3, Sanz-Aparicio J1, González B1.
  • The Biochemical journal.Biochem J.2014 Nov 1;463(3):319-28. doi: 10.1042/BJ20140757.
  • IP3-3K [Ins(1,4,5)P3 3-kinase] is a key enzyme that catalyses the synthesis of Ins(1,3,4,5)P4, using Ins(1,4,5)P3 and ATP as substrates. Both inositides, substrate and product, present crucial roles in the cell. Ins(1,4,5)P3 is a key point in Ca2+ metabolism that promotes Ca2+ release from intracell
  • PMID 25101901
  • Regulation of Gβγi-Dependent PLC-β3 Activity in Smooth Muscle: Inhibitory Phosphorylation of PLC-β3 by PKA and PKG and Stimulatory Phosphorylation of Gαi-GTPase-Activating Protein RGS2 by PKG.
  • Nalli AD1, Kumar DP, Al-Shboul O, Mahavadi S, Kuemmerle JF, Grider JR, Murthy KS.
  • Cell biochemistry and biophysics.Cell Biochem Biophys.2014 Nov;70(2):867-80. doi: 10.1007/s12013-014-9992-6.
  • In gastrointestinal smooth muscle, agonists that bind to Gi-coupled receptors activate preferentially PLC-β3 via Gβγ to stimulate phosphoinositide (PI) hydrolysis and generate inositol 1,4,5-trisphosphate (IP3) leading to IP3-dependent Ca(2+) release and muscle contraction. In the present study,
  • PMID 24777815


  • Role of Inositol-1,4,5-Trisphosphate Receptor in the Regulation of Calcium Transients in Neonatal Rat Ventricular Myocytes
  • Zeng Zheng,Zhang Heping,Lin Na [他]
  • Journal of pharmacological sciences 126(1), 37-46, 2014-09
  • NAID 40020200052
  • Role of Inositol-1,4,5-Trisphosphate Receptor in the Regulation of Calcium Transients in Neonatal Rat Ventricular Myocytes
  • Zeng Zheng,Zhang Heping,Lin Na,Kang Man,Zheng Yuanyuan,Li Chen,Xu Pingxiang,Wu Yongquan,Luo Dali
  • Journal of Pharmacological Sciences 126(1), 37-46, 2014
  • … This study determined the regulatory effect of inositol 1,4,5-trisphosphate receptors (IP3Rs) on the basal Ca2+ transients in cardiomyocytes. …
  • NAID 130004677803
  • Current Perspective : Regulatory Mechanisms and Pathophysiological Significance of IP₃ Receptors and Ryanodine Receptors in Drug Dependence
  • Mizuno Koji,Kurokawa Kazuhiro,Ohkuma Seitaro
  • Journal of pharmacological sciences 123(4), 306-311, 2013-12
  • NAID 40019923730


イノシトール-1,4,5-三リン酸とも呼ばれる。 ジアシル ... 細胞質に拡散する。 IP3は、 細胞膜に存在するリン脂質であるホスファチジルイノシトール-4,5-二リン酸が ホスホリパーゼCによって加水分解されて生成する。 ... MeSH Inositol+1,4,5- Trisphosphate (英語) ...
The inositol trisphosphate trianion. Inositol trisphosphate or inositol 1,4,5- trisphosphate (also commonly known as triphosphoinositol; abbreviated InsP3 or IP3), together with diacylglycerol (DAG), is a secondary messenger molecule used in ...


Inositol 1,4,5-trisphosphate.svgmyo-Inositol 1,4,5-trisphosphate  Inositol 1,4,5-trisphosphate 3-kinases Pharmacology Journal Club-March 1/97 PaperInositol 1, 4-5-trisphosphate (IP3 Inositol -( 1 , 4 , 5 )- trisphosphate

リンク元イノシトール1,4,5-トリスリン酸」「inositol 1,4,5-triphosphate」「イノシトール1,4,5-三リン酸」「IP3
拡張検索inositol 1,4,5-trisphosphate receptor」「myo-inositol 1,4,5-trisphosphate



inositol 1,4,5-trisphosphate
イノシトール三リン酸 inositol trisphosphateIP3
イノシトールmyo-inositol 1,4,5-trisphosphate

  • 細胞内二次メッセンジャー;カルシウム遊離
  • シグナル伝達に関わる。

inositol 1,4,5-triphosphate」


;関:inositol 1

inositol 1,4,5-trisphosphatemyo-inositol 1,4,5-trisphosphate
  • inositol 1,4,5-trisphosphate



inositol 1
  • inositol 1,4,5-trisphosphate


  [★] イノシトール1,4,5-トリスリン酸 inositol 1,4,5-trisphosphate

inositol 1,4,5-trisphosphate receptor」

  [★] イノシトール1,4,5-三リン酸受容体イノシトール三リン酸受容体イノシトール三リン酸レセプターイノシトール3リン酸受容体イノシトール3リン酸レセプターIP3 receptorIP3R

myo-inositol 1,4,5-trisphosphate」



inositol 1,4,5-triphosphateinositol 1,4,5-trisphosphate





WordNet   license wordnet

「an optically inactive alcohol that is a component of the vitamin B complex」