calmodulin kinase

カルモジュリンキナーゼ

関

calcium-calmodulin-dependent protein kinase、calmodulin-dependent protein kinase、CaM kinase、CaMK

WordNet

1. an enzyme that catalyzes the conversion of a proenzyme to an active enzyme
2. the basic unit of money in Papua New Guinea

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2018/03/22 18:49:59」(JST)

wiki en

[Wiki en表示]

CAMK, also written as CaMK, is an abbreviation for the Ca²⁺/calmodulin-dependent protein kinase class of enzymes. CAMKs are activated by increases in the concentration of intracellular calcium ions (Ca²⁺) and transfers phosphates from ATP to defined serine or threonine residues in other proteins. Activated CAMK is involved in the phosphorylation of transcription factors and therefore, in the regulation of expression of responding genes. Members of this enzyme class include:

• CAMKI
  • CAMKIα
  • CAMKIβ
  • CAMKIδ
  • CAMKIγ
• CAMKII
  • CAMKIIα
  • CAMKIIβ
  • CAMKIIδ
  • CAMKIIγ
• CAMKIII
• CAMKIV

UpToDate Contents

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• 1. ホスホリラーゼbキナーゼ欠損症 phosphorylase b kinase deficiency
• 2. ホスホグリセリン酸キナーゼ欠損症およびホスホグリセリン酸ムターゼ欠損症 phosphoglycerate kinase deficiency and phosphoglycerate mutase deficiency
• 3. 未分化リンパ腫キナーゼ（ALK）融合癌遺伝子陽性非小細胞肺癌 anaplastic lymphoma kinase alk fusion oncogene positive non small cell lung cancer
• 4. 自然早産の病因 pathogenesis of spontaneous preterm birth
• 5. 複合免疫不全 combined immunodeficiencies

English Journal

• Panaxydol, a component of Panax ginseng, induces apoptosis in cancer cells through EGFR activation and ER stress and inhibits tumor growth in mouse models.

• Kim HS1,2, Lim JM1,2, Kim JY1,2, Kim Y1,2, Park S1,2, Sohn J1,2.
• International journal of cancer. Journal international du cancer.Int J Cancer.2016 Mar 15;138(6):1432-41. doi: 10.1002/ijc.29879. Epub 2015 Oct 30.
• We reported previously that panaxydol, a component of Panax ginseng roots, induced mitochondria-mediated apoptosis preferentially in transformed cells. This study demonstrates that EGFR activation and the resulting ER stress mediate panaxydol-induced apoptosis, and that panaxydol suppresses in vivo
• PMID 26421996

• Parathyroid hormone induces adipocyte lipolysis via PKA-mediated phosphorylation of hormone-sensitive lipase.

• Larsson S1, Jones HA2, Göransson O3, Degerman E4, Holm C5.
• Cellular signalling.Cell Signal.2016 Mar;28(3):204-13. doi: 10.1016/j.cellsig.2015.12.012. Epub 2015 Dec 23.
• Parathyroid hormone (PTH) is secreted from the parathyroid glands in response to low plasma calcium levels. Besides its classical actions on bone and kidney, PTH may have other important effects, including metabolic effects, as suggested for instance by increased prevalence of insulin resistance and
• PMID 26724218

• Pathogen-associated molecular patterns activate expression of genes involved in cell proliferation, immunity and detoxification in the amebocyte-producing organ of the snail Biomphalaria glabrata.

• Zhang SM1, Loker ES2, Sullivan JT3.
• Developmental and comparative immunology.Dev Comp Immunol.2016 Mar;56:25-36. doi: 10.1016/j.dci.2015.11.008. Epub 2015 Nov 22.
• The anterior pericardial wall of the snail Biomphalaria glabrata has been identified as a site of hemocyte production, hence has been named the amebocyte-producing organ (APO). A number of studies have shown that exogenous abiotic and biotic substances, including pathogen associated molecular patter
• PMID 26592964

Japanese Journal

• Lipopolysaccharide-induced serotonin transporter up-regulation involves PKG-I and p38MAPK activation partially through A3 adenosine receptor

• BioScience Trends 9(6), 367-376, 2016
• NAID 130005120097

• Inhibition of histone deacetylases enhances the function of serotoninergic neurons in organotypic raphe slice cultures.

• Neuroscience letters 593, 72-77, 2015-04-23
• NAID 120005657906

• Jieduquyuziyin prescription suppresses IL-17 production and Th17 activity in MRL/lpr mice by inhibiting expression of Ca²⁺/calmodulin-dependent protein kinase-4

• Journal of natural medicines 69(3), 349-357, 2015
• NAID 40020494359

Related Links

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• Calmodulin Kinase | Calmodulin

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★リンクテーブル★

リンク元	「calmodulin-dependent protein kinase」「calcium-calmodulin-dependent protein kinase」「CaM kinase」「CaMK」「カルモジュリンキナーゼ」
拡張検索	「calmodulin kinase II」「calmodulin kinase I」「calmodulin kinase IV」
関連記事	「kinase」「calmodulin」

「calmodulin-dependent protein kinase」

　　[★]

カルモジュリン依存性プロテインキナーゼ、カルモジュリン依存性キナーゼ

関

calcium-calmodulin-dependent protein kinase、calmodulin kinase、CaM kinase、CaMK

「calcium-calmodulin-dependent protein kinase」

　　[★]

カルシウム・カルモジュリン依存性プロテインキナーゼ、カルシウムカルモジュリン依存性キナーゼ

関

calmodulin kinase、calmodulin-dependent protein kinase

「CaM kinase」

　　[★]

カルモジュリンキナーゼ、カルモジュリン依存性キナーゼ、CaMキナーゼ

関

calmodulin kinase、calmodulin-dependent protein kinase、CaMK

「CaMK」

　　[★]

カルモジュリンキナーゼ、カルモジュリン依存性プロテインキナーゼ

関

calmodulin kinase、calmodulin-dependent protein kinase、CaM kinase

「カルモジュリンキナーゼ」

　　[★]

英

calmodulin kinase, CaM-kinase

関

カルモジュリン

「calmodulin kinase II」

　　[★]

• カルモジュリンキナーゼII、カルモジュリン依存性プロテインキナーゼII

関

calmodulin-dependent protein kinase II、CaM KII、CaM kinase II、CaMKII

「calmodulin kinase I」

　　[★]

• カルモジュリンキナーゼI、カルモジュリン依存性プロテインキナーゼI

関

calmodulin-dependent protein kinase I、CaM KI、CaM kinase I、CaMKI

「calmodulin kinase IV」

　　[★]

• カルモジュリンキナーゼIV、カルモジュリン依存性キナーゼIV

関

CaM KIV、CaMKIV

「kinase」

　　[★] キナーゼ カイネース リン酸化酵素 phosphoenzyme phosphotransferase 　

「calmodulin」

　　[★] カルモジュリン CaM