WordNet

an impairment of health or a condition of abnormal functioning
caused by or altered by or manifesting disease or pathology; "diseased tonsils"; "a morbid growth"; "pathologic tissue"; "pathological bodily processes" (同)morbid, pathologic, pathological
of or relating to or involved in hematology (同)haematological, hematological

PrepTutorEJDIC

(体の)『病気』,疾患 / (精神・道徳などの)病気,病弊
女性の話術芸人 =diseur
病気にかかった / 病的な,不健全な(morbid)

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2019/04/16 07:31:21」(JST)

wiki en

Hematologic diseases are disorders which primarily affect the blood. Hematology includes the study of these disorders.

Myeloid

Hemoglobinopathies (congenital abnormality of the hemoglobin molecule or of the rate of hemoglobin synthesis)
- Sickle-cell disease
- Thalassemia
- Methemoglobinemia
Anemias (lack of red blood cells or hemoglobin)
- Iron deficiency anemia
- Megaloblastic anemia
  - Vitamin B₁₂ deficiency
    - Pernicious anemia
  - Folate deficiency
- Hemolytic anemias (destruction of red blood cells)
  - Genetic disorders of RBC membrane
    - Hereditary spherocytosis
    - Hereditary elliptocytosis
    - Congenital dyserythropoietic anemia
  - Genetic disorders of RBC metabolism
    - Glucose-6-phosphate dehydrogenase deficiency (G6PD)
    - Pyruvate kinase deficiency
  - Immune mediated hemolytic anemia (direct Coombs test is positive)
    - Autoimmune hemolytic anemia
      - Warm antibody autoimmune hemolytic anemia
        Idiopathic
        
        Systemic lupus erythematosus (SLE)
        
        Evans' syndrome (antiplatelet antibodies and hemolytic antibodies)
      - Cold autoimmune hemolytic anemia
        Cold agglutinin disease
        
        Paroxysmal cold hemoglobinuria (rare)
        
        Infectious mononucleosis
    - Alloimmune hemolytic anemia
      - Hemolytic disease of the newborn (HDN)
        Rh disease (Rh D)
        
        ABO hemolytic disease of the newborn
        
        Anti-Kell hemolytic disease of the newborn
        
        Rhesus c hemolytic disease of the newborn
        
        Rhesus E hemolytic disease of the newborn
        
        Other blood group incompatibility (RhC, Rhe, Kid, Duffy, MN, P and others)
    - Drug induced immune mediated hemolytic anemia
      - Penicillin (high dose)
      - Methyldopa
  - Hemoglobinopathies (where these is an unstable or crystalline hemoglobin)
  - Paroxysmal nocturnal hemoglobinuria (rare acquired clonal disorder of red blood cell surface proteins)
  - Direct physical damage to RBCs
    - Microangiopathic hemolytic anemia
    - Secondary to artificial heart valve(s)
- Aplastic anemia
  - Fanconi anemia
  - Diamond-Blackfan anemia (inherited pure red cell aplasia)
  - Acquired pure red cell aplasia
Decreased numbers of cells
- Myelodysplastic syndrome
- Myelofibrosis
- Neutropenia (decrease in the number of neutrophils)
- Agranulocytosis
- Glanzmann's thrombasthenia
- Thrombocytopenia (decrease in the number of platelets)
  - Idiopathic thrombocytopenic purpura (ITP)
  - Thrombotic thrombocytopenic purpura (TTP)
  - Heparin-induced thrombocytopenia (HIT)
Myeloproliferative disorders (Increased numbers of cells)
- Polycythemia vera (increase in the number of cells in general)
- Erythrocytosis (increase in the number of red blood cells)
- Leukocytosis (increase in the number of white blood cells)
- Thrombocytosis (increase in the number of platelets)
- Myeloproliferative disorder
- Transient myeloproliferative disease
Coagulopathies (disorders of bleeding and coagulation)
- Thrombocytosis
- Recurrent thrombosis
- Disseminated intravascular coagulation
- Disorders of clotting proteins
  - Hemophilia
    - Hemophilia A
    - Hemophilia B (also known as Christmas disease)
    - Hemophilia C
  - Von Willebrand disease
  - Disseminated intravascular coagulation
  - Protein S deficiency
  - Antiphospholipid syndrome
- Disorders of platelets
  - Thrombocytopenia
  - Glanzmann's thrombasthenia
  - Wiskott-Aldrich syndrome

Hematological malignancies

Hematological malignancies
- Lymphomas
  - Hodgkin's disease
  - Non-Hodgkin's lymphoma {includes the next five entries}
    - Burkitt's lymphoma
    - Anaplastic large cell lymphoma
    - Splenic marginal zone lymphoma
    - Hepatosplenic T-cell lymphoma
    - Angioimmunoblastic T-cell lymphoma (AILT)
- Myelomas
  - Multiple myeloma
  - Waldenström macroglobulinemia
  - Plasmacytoma
- Leukemias increased WBC
  - Acute lymphocytic leukemia (ALL)
  - Chronic lymphocytic leukemia (CLL){now included in theCLL/SCLL type NHL}
  - Acute myelogenous leukemia (AML)
  - Acute megakaryoblastic leukemia (AMKL), a sub-type of acute myelogenous leukemia
  - Chronic Idiopathic Myelofibrosis (MF)
  - Chronic myelogenous leukemia (CML)
  - T-cell prolymphocytic leukemia (T-PLL)
  - B-cell prolymphocytic leukemia (B-PLL)
  - Chronic neutrophilic leukemia (CNL)
  - Hairy cell leukemia (HCL)
  - T-cell large granular lymphocyte leukemia (T-LGL)
  - Aggressive NK-cell leukemia

Miscellaneous

Hemochromatosis
Asplenia
Hypersplenism
- Gaucher's disease
Monoclonal gammopathy of undetermined significance
Hemophagocytic lymphohistiocytosis
Tempi syndrome

Hematological changes secondary to non-hematological disorders

Anemia of chronic disease
Infectious mononucleosis
AIDS
Malaria
Leishmaniasis

References

External links

http://www.hematologic.niddk.nih.gov/info/index.htm

UpToDate Contents

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1. 血液悪性腫瘍およびリンパ悪性腫瘍の遺伝的異常genetic abnormalities in hematologic and lymphoid malignancies [show details]
…suppressor genes, activation of oncogenes, and general genomic instability. The vast majority of human hematologic neoplasms are caused by the clonal expansion of a single cell that has acquired a somatic mutation …
2. アルコール性脂肪性肝炎およびアルコール性肝硬変の臨床症状および診断clinical manifestations and diagnosis of alcoholic fatty liver disease and alcoholic cirrhosis [show details]
…hepatitis. Patients who are malnourished or who have cirrhosis may have low albumin levels. Hematologic findings in patients with alcoholic liver disease may include thrombocytopenia, anemia, an elevated…
3. 関節リウマチの血液学的所見hematologic manifestations of rheumatoid arthritis [show details]
… Patients with rheumatoid arthritis (RA) may exhibit a variety of hematologic abnormalities. Common changes associated with active disease include anemia of chronic disease (ACD; also termed anemia of …
4. 全身性エリテマトーデスの血液学的異常hematologic manifestations of systemic lupus erythematosus [show details]
… Hematologic abnormalities are common in systemic lupus erythematosus (SLE), both at the time of diagnosis and throughout the course of the disease. The major hematologic manifestations of SLE include …
5. 全身性肥満細胞症：病型の判定systemic mastocytosis determining the subtype of disease [show details]
…criteria for SM and another hematologic disorder according to the World Health Organization (WHO) criteria are classified as "systemic mastocytosis with an associated hematologic neoplasm" (SM-AHN). This …

English Journal

Haemolytic anaemia and hepatocitolysis associated with hypermagnesaemia by repeated exposures to copper-calcium fungicides.

Bălăeţ C1,2, Coculescu BI1,3,4, Bălăeţ M5, Manole G3,6, Dincă GV3.
Journal of enzyme inhibition and medicinal chemistry.J Enzyme Inhib Med Chem.2018 Dec;33(1):184-189. doi: 10.1080/14756366.2017.1409745.
PMID 29231762

Hypomethylation-mediated H19 overexpression increases the risk of disease evolution through the association with BCR-ABL transcript in chronic myeloid leukemia.

Zhou JD1,2, Lin J2,3, Zhang TJ1,2, Ma JC2,3, Li XX1,2, Wen XM2,3, Guo H2,3, Xu ZJ2,3, Deng ZQ2,3, Zhang W1,2, Qian J1,2.
Journal of cellular physiology.J Cell Physiol.2018 Mar;233(3):2444-2450. doi: 10.1002/jcp.26119. Epub 2017 Aug 30.
PMID 28776669

Japanese Journal

研究・症例悪性リンパ腫治療後に器質化肺炎を発症した1例

澤田哲郎,杉山幸比古,間藤尚子 [他]
日本胸部臨床 74(4), 463-470, 2015-04
NAID 40020423440

Effects of low-dose G-CSF formulation on hematology in healthy horses after long-distance transportation

, , , , , , , ,
Journal of Veterinary Medical Science advpub(0), 2015
… Clinical examinations and hematologic analyses were performed on all horses before and after transportation. …
NAID 130004781075

「blood disease」

Hematologic disease
Specialty	Hematology

　　[★]

血液病、血液疾患

関: blood disorder、blood dyscrasia、haematological disease、haematological disorder、hematologic disease、hematologic disorder、hematological disease、hematological disorder、hemopathy

「血液疾患」

　　[★]

英: hematologic disease、blood dyscrasia、blood disorder、blood disease、hematological disorder、((古))haematological disorder、hemopathy
関: 血液病、血液障害

「blood disorder」

　　[★]

血液疾患、血液障害

関: blood disease、blood dyscrasia、haematological disorder、hematologic disease、hematological disorder、hemopathy

「hemopathy」

　　[★]

血液疾患

関: blood disease、blood disorder、blood dyscrasia、haematological disorder、hematologic disease、hematological disorder

「hematological disorder」

　　[★]