dearth

出典: meddic

  • n.
deficiencydeficientdeficitdepletiondeprivationdeprivein shortinsufficiencyinsufficientlackpaucityscarcescarcityshortshortageshortnessstarve

WordNet   license wordnet

「an acute insufficiency」
famine, shortage

WordNet   license wordnet

「an insufficient quantity or number」
paucity

PrepTutorEJDIC   license prepejdic

「(人・物の)不足,欠乏(lack, scarcity)《+『of』+『名』》」

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2013/01/28 16:10:21」(JST)

wiki en

[Wiki en表示]

UpToDate Contents

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

英文文献

  • Mice lacking Nf1 in osteochondroprogenitor cells display skeletal dysplasia similar to patients with neurofibromatosis type I.
  • Wang W, Nyman JS, Ono K, Stevenson DA, Yang X, Elefteriou F.AbstractMutations in NF1 cause neurofibromatosis type I (NF1), a disorder characterized, among other clinical manifestations, by generalized and focal bony lesions. Dystrophic scoliosis and tibial pseudoarthrosis are the most severe skeletal manifestations for which treatment is not satisfactory, emphasizing the dearth of knowledge related to the biology of NF1 in bone cells. Using reporter mice, we report here that the mouse Col2α1-Cre promoter (collagen, type II, alpha 1) is active not only in chondrocytes but also in adult bone marrow osteoprogenitors giving rise to osteoblasts. Based on this finding, we crossed the Col2α1-Cre transgenic and Nf1(flox/flox) mice to determine whether loss of Nf1 in axial and appendicular osteochondroprogenitors recapitulates the skeletal abnormalities of NF1 patients. By microtomographic and X-rays studies, we show that Nf1(Col2)(-/-) mice display progressive scoliosis and kyphosis, tibial bowing and abnormalities in skull and anterior chest wall formation. These defects were accompanied by a low bone mass phenotype, high bone cortical porosity, osteoidosis, increased osteoclastogenesis and decreased osteoblast number, as quantified by histomorphometry and 3D-microtomography. Loss of Nf1 in osteochondroprogenitors also caused severe short stature and intervertebral disc defects. Blockade of the RAS/ERK activation characteristic of Nf1(-/-) osteoprogenitors by lovastatin during embryonic development could attenuate the increased cortical porosity observed in mutant pups. These data and the skeletal similarities between this mouse model and NF1 patients thus suggest that activation of the RAS/ERK pathway by Nf1 loss-of-function in osteochondroprogenitors is responsible for the vertebral and tibia lesions in NF1 patients, and that this molecular signature may represent a good therapeutic target.
  • Human molecular genetics.Hum Mol Genet.2011 Oct 15;20(20):3910-24. Epub 2011 Jul 14.
  • Mutations in NF1 cause neurofibromatosis type I (NF1), a disorder characterized, among other clinical manifestations, by generalized and focal bony lesions. Dystrophic scoliosis and tibial pseudoarthrosis are the most severe skeletal manifestations for which treatment is not satisfactory, emphasizin
  • PMID 21757497
  • Imagery and pain: the prevalence, characteristics, and potency of imagery associated with pain.
  • Philips HC.SourceBack In Motion Rehabilitation Center, Richmond, Canada.
  • Behavioural and cognitive psychotherapy.Behav Cogn Psychother.2011 Oct;39(5):523-40.
  • Background: There is a dearth of information about imagery in pain sufferers. Aim: The aim of this study was to collect data on the characteristics, prevalence, and potency of imagery associated with pain. Method: The images of 59 pain sufferers were assessed by means of a semi-structured interview.
  • PMID 21878137
  • Resveratrol ameliorates TNFα-mediated suppression of erythropoiesis in human CD34(+) cells via modulation of NF-κB signalling.
  • Jeong JY, Silver M, Parnes A, Nikiforow S, Berliner N, Vanasse GJ.SourceDepartment of Medicine, Brigham and Women's Hospital, Harvard Medical School Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • British journal of haematology.Br J Haematol.2011 Oct;155(1):93-101. doi: 10.1111/j.1365-2141.2011.08800.x. Epub 2011 Jul 18.
  • Overexpression of pro-inflammatory cytokines, including tumour necrosis factor alpha (TNFα), has been implicated in the pathogenesis of anaemia of inflammation. TNFα suppresses erythroid colony formation via both direct and indirect effects on haematopoietic progenitors, often involving activation
  • PMID 21762122

和文文献

  • 糸球体疾患--質の高い臨床試験が少ないのはなぜか
  • Leaf David E.,Appel Gerald B.,Radhakrishnan Jai
  • Kidney international selections 9(1), 15-20, 2011
  • NAID 40018711929
  • 農芸教育の提唱(5) : 学校教育の場における育てる指導者不足の背景
  • 松尾 英輔
  • 日本農業教育学会誌 41(2), 75-84, 2010-11-30
  • NAID 10027896207
  • カーボンナノチューブ充てんゴムの卓越した特性とその応用
  • 野口 徹,植木 宏之,犬飼 茂樹,新原 健一,伊藤 正栄,竹内 健司,遠藤 守信
  • 日本ゴム協會誌 83(11), 354-360, 2010-11-15
  • … Today, with the dearth of easy-to-reach reservoirs, the oil and gas industry is conducting more of its exploration and exploitation activities in difficult-to-reach and harsh environments. …
  • NAID 10027128395

関連リンク

Dearth definition at Dictionary.com, a free online dictionary with pronunciation, synonyms and translation. Look it up now!
20 Jul 2011 ... While smiles were rare enough in a place like the Pentagon ...

関連画像


押しても画像が表示されない場合はサーバが混雑しています。2週間ほどあけて、再度押下してください。


★リンクテーブル★
先読み欠乏
リンク元short」「deficit」「starve」「insufficiency」「lack
関連記事dear

欠乏」

  [★]

deficit
欠乏症 deficiency
欠損
  • 不十分な、不足した、不完全な、欠陥のある状態。


short」

  [★]

  • adj.
abbreviatedbrevisbriefdearthdeficitin shortinsufficiencyinsufficientlackpaucitypoorscantscantyscarcescarcityshortageshortness

WordNet   license wordnet

「without possessing something at the time it is contractually sold; "he made his fortune by selling short just before the crash"」

WordNet   license wordnet

「the location on a baseball field where the shortstop is stationed」

WordNet   license wordnet

「low in stature; not tall; "he was short and stocky"; "short in stature"; "a short smokestack"; "a little man"」
little

WordNet   license wordnet

「lacking foresight or scope; "a short view of the problem"; "shortsighted policies"; "shortsighted critics derided the plan"; "myopic thinking"」
shortsighted, unforesightful, myopic

WordNet   license wordnet

「at a disadvantage; "I was caught short"」
unawares

WordNet   license wordnet

「(primarily spatial sense) having little length or lacking in length; "short skirts"; "short hair"; "the board was a foot short"; "a short toss"」

WordNet   license wordnet

「at some point or distance before a goal is reached; "he fell short of our expectations"」

WordNet   license wordnet

「clean across; "the car''s axle snapped short"」

WordNet   license wordnet

「not holding securities or commodities that one sells in expectation of a fall in prices; "a short sale"; "short in cotton"」

WordNet   license wordnet

「of speech sounds or syllables of relatively short duration; "the English vowel sounds in `pat'', `pet'', `pit'', `pot'', putt'' are short"」

WordNet   license wordnet

「primarily temporal sense; indicating or being or seeming to be limited in duration; "a short life"; "a short flight"; "a short holiday"; "a short story"; "only a few short months"」

WordNet   license wordnet

「so as to interrupt; "She took him up short before he could continue"」

WordNet   license wordnet

「tending to crumble or break into flakes due to a large amount of shortening; "shortbread is a short crumbly cookie"; "a short flaky pie crust"」

PrepTutorEJDIC   license prepejdic

「(長さ・時間・距離などが)『短い』,近い・(人が)『背が低い』・(数量・期間などが)不足の』,乏しい;目標(標準)に達しない・(文などが)『簡潔な』,手短な・『そっけない』,ぞんぞいな,無愛想な・(ケーキなどが)かりかりする,さくさくする・(母音・音節が)短い;(詩の行の母音が)強勢のない・急に,突然・短いもの;欠けているもの・短篇映画(short movie, short subject) ・=short circuit・《複数形で》不足,欠損 / …‘を'短絡させる,ショートさせる / 短絡する,ショートする」

deficit」

  [★]

  • n.
  • 欠損、不足/不足額、赤字(⇔surplus)。(機能性の)障害。不利な立場/条件、劣性
agenesis, dearth, defect, defective, deficiency, deficient, deletion, deletional, depletion, deprivation, deprive, drawback, fault, flaw, in short, insufficiency, insufficient, lack, miss, missing, paucity, scarce, scarcity, short, shortage, shortness, starve

WordNet   license wordnet

「(sports) the score by which a team or individual is losing」

WordNet   license wordnet

「a deficiency or failure in neurological or mental functioning; "the people concerned have a deficit in verbal memory"; "they have serious linguistic deficits"」

WordNet   license wordnet

「an excess of liabilities over assets (usually over a certain period); "last year there was a serious budgetary deficit"」

WordNet   license wordnet

「the property of being an amount by which something is less than expected or required; "new blood vessels bud out from the already dilated vascular bed to make up the nutritional deficit"」
shortage, shortfall

PrepTutorEJDIC   license prepejdic

「(金銭の)不足額,赤字」

starve」

  [★]

  • v.
dearthdeficiencydeficientdeficitdepletiondeprivationdeprivefaminefastingfood deprivationhungerlackpaucityscarcescarcitystarvation

WordNet   license wordnet

「deprive of a necessity and cause suffering; "he is starving her of love"; "The engine was starved of fuel"」

WordNet   license wordnet

「deprive of food; "They starved the prisoners"」
famish

WordNet   license wordnet

「die of food deprivation; "The political prisoners starved to death"; "Many famished in the countryside during the drought"」
famish

WordNet   license wordnet

「be hungry; go without food; "Let''s eat--I''m starving!"」
hunger, famish

PrepTutorEJDIC   license prepejdic

「『餓死する』 / (…を)切望する,(…に)飢える《+『for』+『名』》 / 《話》空腹である,ひもじい / …‘を'飢え死にさせる / 〈人〉‘を'飢えさせる,腹ぺこにさせる / (…を)…‘に'切望させる,(…の)欠乏を感じさせる《+『名』+『for(of)』+『名』》」

insufficiency」

  [★]

  • n.
dearthdeficientdeficitdysfunctionfailingfailurehypofunctionimperfectain shortinadequateincompetenceinsufficientinsufficientlylacklowmalfunctionpaucitypoorlyregurgitationscantyscarcescarcityshortshortageshortnessstun

WordNet   license wordnet

「a lack of competence; "pointed out the insufficiencies in my report"; "juvenile offenses often reflect an inadequacy in the parents"」
inadequacy

WordNet   license wordnet

「(pathology) inability of a bodily part or organ to function normally」

WordNet   license wordnet

「lack of an adequate quantity or number; "the inadequacy of unemployment benefits"」
inadequacy, deficiency

PrepTutorEJDIC   license prepejdic

「不十分な[点],不足;不適当,不向き」

lack」

  [★]

  • n.
  • v.
  • 欠乏する、欠く
absenceabsentdearthdefectivedeficiencydeficientdeficitdepletiondeprivationdeprivedevoidin shortinsufficiencyinsufficientpaucityscarcescarcityshortshortageshortnessstarve

WordNet   license wordnet

「the state of needing something that is absent or unavailable; "there is a serious lack of insight into the problem"; "water is the critical deficiency in desert regions"; "for want of a nail the shoe was lost"」
deficiency, want

PrepTutorEJDIC   license prepejdic

「…‘を'『欠く』,‘が'ない(受動態にできない) / (…になるまでに)…‘だけ'不足する《+『名』+『of』[『being』]+『名』》 / 〈U〉《時にa~》(必要なものの)『欠乏』,不足;(…が)ないこと《+『of』+『名』》 / 〈C〉欠けて(不足して)いるもの」

dear」

  [★]

WordNet   license wordnet

「with or in a close or intimate relationship; "a good friend"; "my sisters and brothers are near and dear"」
good, near

PrepTutorEJDIC   license prepejdic

「『親愛な,かわいい』(much loved) / (手紙の書き出しのあいさつの)『親愛なる』,尊敬する / 『大事な』,貴重な;(…にとって)大事な《+『to』+『名』》(precious) / ‐高い/,高価な / 『高価に』,高く / 『かわいい人』,大切な人,いい子 / 『おや,まあ』(驚き・同情・悲しみ・困惑などを表す)」

WordNet   license wordnet

「earnest; "one''s dearest wish"; "devout wishes for their success"; "heartfelt condolences"」
devout, earnest, heartfelt


"http://meddic.jp/dearth" より作成


★コメント★

[メモ入力エリア]
※コメント5000文字まで
ニックネーム:
コメント:




表示
個人用ツール


  meddic.jp

リンク
連絡