carbonic anhydrase inhibitor

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2015/06/04 08:03:56」(JST)

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  • Synthesis, characterization, antimicrobial activity and carbonic anhydrase enzyme inhibitor effects of salicilaldehyde-N-methyl p-toluenesulfonylhydrazone and its Palladium(II), Cobalt(II) complexes.
  • Alyar S1, Adem Ş2.
  • Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy.Spectrochim Acta A Mol Biomol Spectrosc.2014 Oct 15;131:294-302. doi: 10.1016/j.saa.2014.04.121. Epub 2014 Apr 29.
  • We report the synthesis of the ligand, salicilaldehyde-N-methyl p-toluenesulfonylhydrazone (salptsmh) derived from p-toluenesulfonicacid-1-methylhydrazide (ptsmh) and its Pd(II) and Co(II) metal complexes were synthesized for the first time. The structure of the ligand and their complexes were inves
  • PMID 24835932
  • Cyclic tertiary sulfamates: Selective inhibition of the tumor-associated carbonic anhydrases IX and XII by N- and O-substituted acesulfame derivatives.
  • De Monte C1, Carradori S2, Secci D2, D'Ascenzio M2, Vullo D3, Ceruso M3, Supuran CT4.
  • European journal of medicinal chemistry.Eur J Med Chem.2014 Sep 12;84:240-6. doi: 10.1016/j.ejmech.2014.07.014. Epub 2014 Jul 8.
  • Carbonic anhydrase (hCA) IX and XII isoforms are over-expressed both in primary and in metastatic cell lines of hypoxic tumors and are innovative targets for cancer diagnosis and treatment. On the basis of the importance of the pharmacophoric sulfamate moiety (bioisostere of the sulfonamide group) p
  • PMID 25019479
  • Synthesis of a new series of N(4)-substituted 4-(2-aminoethyl)benzenesulfonamides and their inhibitory effect on human carbonic anhydrase cytosolic isozymes I and II and transmembrane tumor-associated isozymes IX and XII.
  • Sławiński J1, Brzozowski Z2, Zołnowska B2, Szafrański K2, Pogorzelska A2, Vullo D3, Supuran CT3.
  • European journal of medicinal chemistry.Eur J Med Chem.2014 Sep 12;84:59-67. doi: 10.1016/j.ejmech.2014.06.074. Epub 2014 Jul 5.
  • A series of novel N(4)-substituted 4-(2-aminoethyl)benzenesulfonamides 5-17 have been synthesized and investigated as inhibitors of four isoforms of zinc enzyme carbonic anhydrase (CA, EC, that is the cytosolic CA I and II, and tumor-associated isozymes CA IX and XII. Against the human CA I
  • PMID 25016228


  • プロスタグランジン薬,βブロッカー,炭酸脱水酵素阻害剤の3剤併用でコントロール不十分な症例に対するブリモニジン点眼液の追加処方
  • 松浦 一貴,寺坂 祐樹,佐々木 慎一
  • あたらしい眼科 31(7), 1059-1062, 2014-07
  • NAID 40020164236
  • 網膜色素変性に伴う囊胞様黄斑浮腫に炭酸脱水酵素阻害薬の点眼加療が有効と思われた1例 (特集 第67回日本臨床眼科学会講演集(3))
  • 春田 雅俊,佛坂 扶美,山川 良治
  • 臨床眼科 68(5), 713-717, 2014-05
  • NAID 40020081143
  • 炭酸脱水酵素阻害薬 (特集 利尿薬およびそれに関連する話題)


Carbonic anhydrase inhibitors are a class of pharmaceuticals that suppress the activity of carbonic anhydrase. Their clinical use has been established as anti glaucoma agents, diuretics, antiepileptics, in the management of mountain sickness, ...
19 Dec 2012 ... Acetazolamide and methazolamide are carbonic anhydrase inhibitors used as diuretics and in the therapy of glaucoma. Both acetazolamide and methazolamide have been linked to rare cases of clinically apparent ...


Carbonic Anhydrase InhibitorCarbonic Anhydrase Inhibitors; Carbonate Effects on Electrolytes and Renal Carbonic Anhydrase Inhibitors; Carbonate CARBONIC ANHYDRASE INHIBITORCarbonic Anhydrase Inhibitor Mechanism




carbonic anhydrase inhibitor, carbonate dehydratase inhibitor



carbonic anhydrase inhibitor



  • v.
  • 抑制する、阻害する、阻止する

WordNet   license wordnet

「limit, block, or decrease the action or function of; "inhibit the action of the enzyme"; "inhibit the rate of a chemical reaction"」

PrepTutorEJDIC   license prepejdic

「〈感情・欲望・行動・作用など〉‘を'抑制する / (…しないように)〈人〉‘を'抑制する,妨げる《+『名』+『from』+『名』(do『ing』)》」

WordNet   license wordnet

「control and refrain from showing; of emotions, desires, impulses, or behavior」
bottle up, suppress

WordNet   license wordnet

「limit the range or extent of; "Contact between the young was inhibited by strict social customs"」





WordNet   license wordnet

「an abundant nonmetallic tetravalent element occurring in three allotropic forms: amorphous carbon and graphite and diamond; occurs in all organic compounds」
C, atomic number 6

WordNet   license wordnet

「a copy made with carbon paper」
carbon copy

PrepTutorEJDIC   license prepejdic

「『炭素』(化学記号は『C』) / 〈C〉炭素棒 / 〈C〉《時に〈U〉》=carbon paper」



  • n.

WordNet   license wordnet

「a substance that retards or stops an activity」

PrepTutorEJDIC   license prepejdic

「抑制する人(物) / 化学反応抑制剤」



Ccarboncarbonatecarbonic acid