- platelet-rich plasma platelet rich plasma 多血小板血漿
- progressive rubella panencephalitis
- polyribosylribitrol phosphate
- pan retinal photocoagulation 汎網膜光凝固
出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2014/02/15 12:29:55」(JST)[Wiki en表示]
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- 1. 毛孔性紅色粃糠疹 pityriasis rubra pilaris
- 2. 過負荷による（慢性）腱障害のマネージメントの概要 overview of the management of overuse chronic tendinopathy
- 3. 変形性関節症の薬物療法に対する実験的アプローチ investigational approaches to the pharmacologic therapy of osteoarthritis
- 4. Adductor muscle and tendon injury
- 5. ハムストリング筋腱損傷 hamstring muscle and tendon injuries
- Biodegradable borosilicate bioactive glass scaffolds with a trabecular microstructure for bone repair.
- Gu Y1, Wang G2, Zhang X1, Zhang Y2, Zhang C2, Liu X3, Rahaman MN3, Huang W4, Pan H5.Author information 1Department of Materials Science and Engineering, Tongji University, Shanghai 200092, China.2Department of Orthopedic Surgery, Shanghai Sixth People's Hospital, Shanghai Jiao Tong University, Shanghai 200233, China.3Department of Materials Science and Engineering, and Center for Bone and Tissue Repair and Regeneration, Missouri University of Science and Technology, Rolla, MO 65409-0340, USA.4Department of Materials Science and Engineering, Tongji University, Shanghai 200092, China. Electronic address: email@example.comDepartment of Orthopaedics & Traumatology, The University of Hong Kong, 999077, Hong Kong, China.AbstractThree-dimensional porous scaffolds of a borosilicate bioactive glass (designated 13-93B1), with the composition 6Na2O-8K2O-8MgO-22CaO-18B2O3-36SiO2-2P2O5 (mol%), were prepared using a foam replication technique and evaluated in vitro and in vivo. Immersion of the scaffolds for 30days in a simulated body fluid in vitro resulted in partial conversion of the glass to a porous hydroxyapatite composed of fine needle-like particles. The capacity of the scaffolds to support bone formation in vivo was evaluated in non-critical sized defects created in the femoral head of rabbits. Eight weeks post-implantation, the scaffolds were partially converted to hydroxyapatite, and they were well integrated with newly-formed bone. When loaded with platelet-rich plasma (PRP), the scaffolds supported bone regeneration in segmental defects in the diaphysis of rabbit radii. The results indicate that these 13-93B1 scaffolds, loaded with PRP or without PRP, are beneficial for bone repair due to their biocompatibility, conversion to hydroxyapatite, and in vivo bone regenerative properties.
- Materials science & engineering. C, Materials for biological applications.Mater Sci Eng C Mater Biol Appl.2014 Mar 1;36:294-300. doi: 10.1016/j.msec.2013.12.023. Epub 2013 Dec 27.
- Three-dimensional porous scaffolds of a borosilicate bioactive glass (designated 13-93B1), with the composition 6Na2O-8K2O-8MgO-22CaO-18B2O3-36SiO2-2P2O5 (mol%), were prepared using a foam replication technique and evaluated in vitro and in vivo. Immersion of the scaffolds for 30days in a simulated
- PMID 24433915
- Molecular dynamics studies on the NMR and X-ray structures of rabbit prion proteins.
- Zhang J1, Zhang Y2.Author information 1Graduate School of Sciences, Information Technology and Engineering, & Centre of Information and Applied Optimization, The University of Ballarat, Mount Helen Campus, MT Helen, Victoria 3353, Australia. Electronic address: firstname.lastname@example.orgSchool of Basic Medical Sciences, Taishan Medical University, Shandong 271000, China.AbstractPrion diseases, traditionally referred to as transmissible spongiform encephalopathies (TSEs), are invariably fatal and highly infectious neurodegenerative diseases that affect a wide variety of mammalian species, manifesting as scrapie in sheep and goats, bovine spongiform encephalopathy (BSE or mad-cow disease) in cattle, chronic wasting disease in deer and elk, and Creutzfeldt-Jakob diseases, Gerstmann-Sträussler-Scheinker syndrome, fatal familial insomnia, and kulu in humans, etc. These neurodegenerative diseases are caused by the conversion from a soluble normal cellular prion protein (PrP(C)) into insoluble abnormally folded infectious prions (PrP(Sc)), and the conversion of PrP(C) to PrP(Sc) is believed to involve conformational change from a predominantly α-helical protein to one rich in β-sheet structure. Such a conformational change may be amenable to study by molecular dynamics (MD) techniques. For rabbits, classical studies show that they have a low susceptibility to be infected by PrP(Sc), but recently it was reported that rabbit prions can be generated through saPMCA (serial automated Protein Misfolding Cyclic Amplification) in vitro and the rabbit prion is infectious and transmissible. In this paper, we first do a detailed survey on the research advances of rabbit prion protein (RaPrP) and then we perform MD simulations on the NMR and X-ray molecular structures of rabbit prion protein wild-type and mutants. The survey shows to us that rabbits were not challenged directly in vivo with other known prion strains and the saPMCA result did not pass the test of the known BSE strain of cattle. Thus, we might still look rabbits as a prion resistant species. MD results indicate that the three α-helices of the wild-type are stable under the neutral pH environment (but under low pH environment the three α-helices have been unfolded into β-sheets), and the three α-helices of the mutants (I214V and S173N) are unfolded into rich β-sheet structures under the same pH environment. In addition, we found an interesting result that the salt bridges such as ASP201-ARG155, ASP177-ARG163 contribute greatly to the structural stability of RaPrP.
- Journal of theoretical biology.J Theor Biol.2014 Feb 7;342:70-82. doi: 10.1016/j.jtbi.2013.10.005. Epub 2013 Oct 31.
- Prion diseases, traditionally referred to as transmissible spongiform encephalopathies (TSEs), are invariably fatal and highly infectious neurodegenerative diseases that affect a wide variety of mammalian species, manifesting as scrapie in sheep and goats, bovine spongiform encephalopathy (BSE or ma
- PMID 24184221
- Interaction of membrane/lipid rafts with the cytoskeleton: Impact on signaling and function: Membrane/lipid rafts, mediators of cytoskeletal arrangement and cell signaling.
- Head BP1, Patel HH1, Insel PA2.Author information 1VA San Diego Healthcare System, 3350 La Jolla Village Drive, San Diego, CA 92161, USA; Department of Anesthesiology, University of California, San Diego, La Jolla, CA 92093, USA.2Department of Pharmacology, University of California, San Diego, La Jolla, CA 92093, USA; Department of Medicine, University of California, San Diego, La Jolla, CA 92093, USA. Electronic address: email@example.com.AbstractThe plasma membrane in eukaryotic cells contains microdomains that are enriched in certain glycosphingolipids, gangliosides, and sterols (such as cholesterol) to form membrane/lipid rafts (MLR). These regions exist as caveolae, morphologically observable flask-like invaginations, or as a less easily detectable planar form. MLR are scaffolds for many molecular entities, including signaling receptors and ion channels that communicate extracellular stimuli to the intracellular milieu. Much evidence indicates that this organization and/or the clustering of MLR into more active signaling platforms depends upon interactions with and dynamic rearrangement of the cytoskeleton. Several cytoskeletal components and binding partners, as well as enzymes that regulate the cytoskeleton, localize to MLR and help regulate lateral diffusion of membrane proteins and lipids in response to extracellular events (e.g., receptor activation, shear stress, electrical conductance, and nutrient demand). MLR regulate cellular polarity, adherence to the extracellular matrix, signaling events (including ones that affect growth and migration), and are sites of cellular entry of certain pathogens, toxins and nanoparticles. The dynamic interaction between MLR and the underlying cytoskeleton thus regulates many facets of the function of eukaryotic cells and their adaptation to changing environments. Here, we review general features of MLR and caveolae and their role in several aspects of cellular function, including polarity of endothelial and epithelial cells, cell migration, mechanotransduction, lymphocyte activation, neuronal growth and signaling, and a variety of disease settings. This article is part of a Special Issue entitled: Reciprocal influences between cell cytoskeleton and membrane channels, receptors and transporters. Guest Editor: Jean Claude Hervé.
- Biochimica et biophysica acta.Biochim Biophys Acta.2014 Feb;1838(2):532-45. doi: 10.1016/j.bbamem.2013.07.018. Epub 2013 Jul 27.
- The plasma membrane in eukaryotic cells contains microdomains that are enriched in certain glycosphingolipids, gangliosides, and sterols (such as cholesterol) to form membrane/lipid rafts (MLR). These regions exist as caveolae, morphologically observable flask-like invaginations, or as a less easily
- PMID 23899502
- PRP療法 (特集 美容外科・抗加齢医療 : 基本から最先端まで) -- (再生治療)
- 久保田 潤一郎
- Pepars (99), 139-146, 2015-03
- NAID 40020444472
- 抗凝固・抗血小板とアンチエイジング(シリーズ1-1)血小板とアンチエイジング : アンチエイジングにおける多血小板血漿(PRP)療法の有用性(第10回)皮膚のアンチエイジングにおける多血小板血漿(PRP)療法の有用性 : 難治性皮膚潰瘍・褥瘡治療からみた血小板の皮膚軟部組織への影響
- 楠本 健司
- Anti-aging science : 脳心血管抗加齢研究会機関誌 7(1), 49-54, 2015-03
- NAID 40020427711
- 微分不可能な関数を含む非線形方程式系に対するPRP型平滑化スケーリング共役勾配法について (最適化アルゴリズムの進展 : 理論・応用・実装)
- 成島 康史,大谷 亮介,矢部 博
- 数理解析研究所講究録 1931, 67-78, 2015-01
- NAID 110009881115
- 『W-PRP』は自身の血液を使う最先端の皮膚再生療法で、目元のシワ・たるみを切らずに解消します。血小板を使用する再生医療は「PRP療法」という手法が一般的ですが、オザキクリニックでは「PRP療法」をより進化させた『W-PRP ...
- PRP（多血小板血漿）注入による皮膚再生療法に関するご紹介。レーザー治療専門の美容皮膚科シロノクリニックは、日本最大規模の最新レーザー・光治療機器等135台以上完備、症例数15万例以上の実積（グループ総数）。美しく年を ...
|拡張検索||「PRP-OMP vaccine」「PRPP」「PRP vaccine」「PRPP synthetase superactivity」|
- polyribosylribitrol phosphate-outer membrane protein
- 部分寛解 partial remission
- 肺動脈弁閉鎖不全症 肺動脈弁閉鎖不全症 pulmonary regurgitation
- ホスホリラーゼ phosphorylase
- プロゲステロン progesterone
- プロトロンビン比 prothrombin ratio
- (心電図)PR interval