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- 1. BおよびTリンパ球の正常な発生 normal b and t lymphocyte development
- 2. 体液性免疫応答 the humoral immune response
- 3. 胎児および新生児における免疫細胞の発達 the development of immune cells in the fetus and neonate
- 4. 選択的IgA欠損症：臨床症状、病態生理、および診断 selective iga deficiency clinical manifestations pathophysiology and diagnosis
- 5. 分類不能型低ガンマグロブリン血症の病因 pathogenesis of common variable immunodeficiency
English Journal
- Notch and its ligands in alloimmunity and rejection.
- Magee CN1, Riella LV.
- Current opinion in organ transplantation.Curr Opin Organ Transplant.2016 Feb;21(1):15-21. doi: 10.1097/MOT.0000000000000266.
- PURPOSE OF REVIEW: The Notch signaling pathway is known to play a pivotal role in T- and B-cell development and fate, presenting it as an attractive therapeutic target in alloimmunity. This review provides an overview of the mechanisms of Notch signaling, focusing on new insights into its diverse fu
- PMID 26626420
- Biological effects of IL-21 on different immune cells and its role in autoimmune diseases.
- Gharibi T1, Majidi J2, Kazemi T2, Dehghanzadeh R2, Motallebnezhad M2, Babaloo Z3.
- Immunobiology.Immunobiology.2016 Feb;221(2):357-67. doi: 10.1016/j.imbio.2015.09.021. Epub 2015 Oct 1.
- Interleukin-21 (IL-21) is a member of the common γ-chain cytokines with broad pleiotropic actions that affects different immune and nonimmune cells. IL-21 can affect differentiation, proliferation and function of T and B cells; it can also induce the maturation and enhance the cytotoxicity of CD8+
- PMID 26466984
- The Costimulatory Molecule ICOS Regulates Host Th1 and Follicular Th Cell Differentiation in Response to Plasmodium chabaudi chabaudi AS Infection.
- Wikenheiser DJ1, Ghosh D1, Kennedy B1, Stumhofer JS2.
- Journal of immunology (Baltimore, Md. : 1950).J Immunol.2016 Jan 15;196(2):778-91. doi: 10.4049/jimmunol.1403206. Epub 2015 Dec 14.
- Blood-stage Plasmodium chabaudi chabaudi AS infection requires cell- and Ab-mediated immunity to control acute and persistent infection, respectively. ICOS regulates CD4(+) T cell activation and promotes the induction of follicular Th (TFH) cells, CD4(+) T cells that support B cell affinity maturati
- PMID 26667167
Japanese Journal
- 制御性B細胞の分化誘導因子と作用機序に関する検討
- 吉崎 歩,TEDDER Thomas F.
- 日本臨床免疫学会会誌 38(1), 57-64, 2015
- … 近年，B細胞の働きは単に抗体を産生するのみではなく，抗原提示や炎症性サイトカインの産生，T細胞をはじめとする免疫細胞の活性化誘導など，炎症反応において中心的な役割を果たすことが知られるようになってきた．B細胞は炎症反応を誘導するだけでなく，活性化した炎症細胞に作用することで，免疫抑制作用をも発揮することが知られているが，著者らのグループでは，この中でも特にin …
- NAID 130004875952
- The Association of nm23-H1 Expression with a Poor Prognosis in Patients with Peripheral T-Cell Lymphoma, Not Otherwise Specified
- Journal of Clinical and
- … The nm23 genes play critical roles in cellular proliferation, differentiation, oncogenesis, and tumor metastasis. … Peripheral T-cell lymphoma (PTCL) is relatively rare, accounting for only 10% to 15% of non-Hodgkins lymphomas. … We examined whether nm23-H1 is a prognostic factor of peripheral T-cell lymphoma, not otherwise specified (PTCL-NOS). …
- NAID 130004705263
Related Links
- B cell development and differentiation Peter D Burrows, Max D Cooper Division of Developmental and Clinical Immunology, Department of Medicine, Pediatrics and Microbiology, and the Howard Hughes Medical Institute, University of ...
- Research Topics B Cell Development and Differentiation B cell development and differentiation occurs in multiple phases. The initial, antigen-independent phase generates mature, immunocompetent B cells that can bind to a unique ...
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| 関連記事 | 「development」「B」「differentiation」「cell」 |
「development」
- n.
- 関
- buildup、deployment、develop、developmental、emergence、engender、evolution、expand、exploit、exploitation、generate、generation、growth、occur、occurrence、onset、transpire、unfold
「B」
- 気管分岐部下緑
- 補体のalternative pathwayに関わる蛋白質
- Mg2+存在下でC3, B, Dが反応してC3bBbとなり、これがC3転換酵素(C3bBb)あるいはC5転換酵素(C3bBb3b)を形成する。これらはP(properdin)と結合して活性化し、それぞれC3、C5を活性化する
「differentiation」
- n.