関: pulmonary edema

WordNet

supporting or permitting the legal production and sale of alcoholic beverages; "a wet candidate running on a wet platform"; "a wet county"
cause to become wet; "Wet your face"
make ones bed or clothes wet by urinating; "This eight year old boy still wets his bed"
producing or secreting milk; "a wet nurse"; "a wet cow"; "lactating cows" (同)lactating
consisting of or trading in alcoholic liquor; "a wet cargo"; "a wet canteen"
containing moisture or volatile components; "wet paint"
covered or soaked with a liquid such as water; "a wet bathing suit"; "wet sidewalks"; "wet weather"
either of two saclike respiratory organs in the chest of vertebrates; serves to remove carbon dioxide and provide oxygen to the blood

PrepTutorEJDIC

『ぬれた』,湿った,乾いていない / 『雨でぬれた』;雨降りの / 《米》非(反)禁酒主義の / 《英話》《軽べつして》(人が)気が弱い,湿っぽい,からっとしていない / 《the wet》(特に雨後の)湿った地面 / 《the wet》『雨』;雨天 / 《しばしば a wet》《英俗》『酒』 / …‘を'『ぬらす』,湿らせる
『私たちは(が)』,われわれは(が) / 《総称的に》『人は』,われわれは / 《論説・評論などで I の代りに用いて》私たちは,吾人(ごじん)は,筆者は / 《子供・病人などに対して,you の代りに養いて》あなたは / 《君主が公式の場でI の代りに用いて》余は
《しばしば複数形で》『肺』,肺臓
week / width / weight

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/12/28 23:57:49」(JST)

wiki en

Transient tachypnea of the newborn (TTN, TTNB, or "transitory tachypnea of newborn") is a respiratory problem that can be seen in the newborn shortly after delivery. Amongst causes of respiratory distress in term neonates, it is the most common.^[1]^[2] It consists of a period of rapid breathing (higher than the normal range of 40-60 times per minute). It is likely due to retained lung fluid. It is most often seen in 35+ week gestation babies who are delivered by caesarian section without labor. Usually, this condition resolves over 24–48 hours. Treatment is supportive and may include supplemental oxygen and antibiotics. The chest x-ray shows hyperinflation of the lungs including prominent pulmonary vascular markings, flattening of the diaphragm, and fluid in the horizontal fissure of the right lung.

Pathophysiology

Due to the higher incidence of TTN in newborns delivered by caesarean section, it has been postulated that TTN could result from a delayed absorption of fetal lung fluid from the pulmonary lymphatic system. The increased fluid in the lungs leads to increased airway resistance and reduced lung compliance. It is thought this could be from lower levels of circulating catecholamines after a caesarean section, which are believed to be necessary to alter the function of the ENaC channel to absorb excess fluid from the lungs.
Pulmonary immaturity has also been proposed as a causative factor. Levels of phosphatidylglycerol (an indicator of lung maturity) were found to be negative in certain newborns.
Mild surfactant deficiency has also been suggested as a causative factor.

Clinical evaluation

TTN is a diagnosis of exclusion as it is a benign condition that can have symptoms and signs similar to more serious conditions, such as respiratory distress syndrome.^[1] A chest X-ray may show a radiopaque line - fluid - in the horizontal fissure of the right lung, fluid infiltrate throughout alveoli or fluid in individual lung lobes.^[1]

References

^ ^a ^b ^c Lissauer T, Clayden,(2007). Illustrated textbook of paediatrics (3rd ed.). Mosby/Elsevier. p. 162. ISBN 0-7234-3397-6
^ Hermansen CL, Lorah KN (October 2007). "Respiratory distress in the newborn". Am Fam Physician 76 (7): 987–94. PMID 17956068.

3.Cohain JS. When is homebirth safer than hospital birth. Youtube/watch?v=uA91JgnztE0

UpToDate Contents

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1. 新生児の一過性頻呼吸 transient tachypnea of the newborn
2. 新生児における呼吸促迫症候群の病態生理および臨床症状 pathophysiology and clinical manifestations of respiratory distress syndrome in the newborn
3. Overview of approach to lung cancer survivors
4. Anesthesia for open pulmonary resection
5. 新生児呼吸促迫の概要：移行の障害 overview of neonatal respiratory distress disorders of transition

English Journal

Impact of home remediation and household education on indoor air quality, respiratory visits and symptoms in Alaska Native children.

Singleton R1,2, Salkoski AJ3, Bulkow L4, Fish C5, Dobson J6, Albertson L7, Skarada J8, Ritter T9, Kovesi T10, Hennessy TW11.
International journal of circumpolar health.Int J Circumpolar Health.2018 Dec;77(1):1422669. doi: 10.1080/22423982.2017.1422669.
PMID 29393004

Transcriptomic profiling reveals gene expression kinetics in patients with hypoxia and high altitude pulmonary edema.

Yuhong L1, Tana W2, Zhengzhong B3, Feng T3, Qin G3, Yingzhong Y3, Wei G1, Yaping W3, Langelier C4, Rondina MT5, Ge RL6.
Gene.Gene.2018 Apr 20;651:200-205. doi: 10.1016/j.gene.2018.01.052. Epub 2018 Jan 31.
PMID 29366758

Expression level of 12-amino acid triggering receptor on myeloid cells-like transcript 1 derived peptide alleviates lipopolysaccharide-induced acute lung injury in mice.

Shi R1, Zhang J1, Peng Z1, Yuan S1, Gao S1, Chen L1, Yuan Y1.
International journal of molecular medicine.Int J Mol Med.2018 Apr;41(4):2159-2168. doi: 10.3892/ijmm.2018.3443. Epub 2018 Jan 30.
PMID 29393375

Japanese Journal

Relationship between neutrophil influx and oxidative stress in alveolar space in lipopolysaccharide-induced lung injury

Yoshida T.,Nagai K.,Inomata T.,Ito Y.,Betsuyaku T.,Nishimura M.
Respiratory physiology & neurobiology 191, 75-83, 2014-01-15
… We intratracheally administered lipopolysaccharide (LPS) to ICR mice and then collected BAL fluid and lung tissue to determine whether levels of neutrophils and/or myeloperoxidase (MPO) in bronchoalveolar lavage (BAL) fluid reflect lung tissue damage. … Robust neutrophil accumulation into the alveolar space and lung tissue were almost completely abolished at seven days along with oxidative stress markers in the lung. …
NAID 120005411142

多彩な画像所見が腫瘍進展形式を示唆した置換性増殖優位型浸潤性肺腺癌の1例

日比野真,山本紗織,伊東直哉,平島修,大江元樹,近藤哲理
肺癌 54(4), 212-217, 2014
背景．置換性増殖優位型浸潤性腺癌は，以前は粘液非産生性細気管支肺胞上皮癌と呼ばれており，多彩な画像所見を呈する．症例．70歳の男性．7か月間の湿性咳嗽と1か月前からの労作時呼吸困難感を認めて受診した．胸部CTで広範囲に気管支透亮像を伴う浸潤影とメロンの皮様網目状陰影を認め，一部分に小葉中心性のすりガラス陰影を認めた．以上より経気道散布する病変が進行している状態が考えられ，経気管支肺生検の結果，置換 …
NAID 130004687682

Development and Evaluation of Optimized Sucrose Ester Stabilized Oleanolic Acid Nanosuspensions Prepared by Wet Ball Milling with Design of Experiments

Li Wenji,Ng Ka-yun,Heng Paul Wan Sia
Biological and Pharmaceutical Bulletin 37(6), 926-937, 2014
… The aim of this study was to develop optimized sucrose ester (SE) stabilized oleanolic acid (OA) nanosuspensions (NS) for enhanced delivery via wet ball milling by design of experiments (DOE). … In this study, SEOA NS batches were prepared by wet ball milling method. … The in vitro bioefficacy was obtained by methyl thiazolyl tetrazolium (MTT) measurements in A549 human non small cell lung cancer cell line. …
NAID 130004147337

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★リンクテーブル★

リンク元	「浮腫肺」「湿性肺」
関連記事	「wet」

「浮腫肺」

Transient tachypnea of the newborn
Classification and external resources
Specialty	pediatrics
ICD-10	P22.1
ICD-9-CM	770.6
DiseasesDB	32373
MedlinePlus	007233
eMedicine	ped/2597 radio/710