WordNet

varix or varicose condition in which a vein is swollen and tortuous
abnormally enlarged or twisted blood vessel or lymphatic vessel

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1. 表在性下肢静脈の静脈炎および血栓症 phlebitis and thrombosis of the superficial lower extremity veins
2. Causes of primary hypogonadism in males
3. Vulvar lesions: Differential diagnosis based on morphology

English Journal

Distribution and morphology of calcitonin gene-related peptide and substance P immunoreactive axons in the whole-mount atria of mice.

Li L1, Hatcher JT1, Hoover DB2, Gu H3, Wurster RD4, Cheng ZJ5.Author information 1Biomolecular Science Center, Burnett School of Biomedical Sciences, College of Medicine, University of Central Florida, Orlando, FL 32816, United States.2Department of Biomedical Sciences, Quillen College of Medicine, East Tennessee State University, Johnson City, TN 37614, United States.3Department of Anesthesia, University of Iowa Hospital and Clinics, Iowa City, IA 52242, United States.4Department of Physiology, Loyola University, Stritch School of Medicine, Maywood, IL 60153, United States.5Biomolecular Science Center, Burnett School of Biomedical Sciences, College of Medicine, University of Central Florida, Orlando, FL 32816, United States. Electronic address: zcheng@mail.ucf.edu.AbstractThe murine model has been used to investigate the role of cardiac sensory axons in various disease states. However, the distribution and morphological structures of cardiac nociceptive axons in normal murine tissues have not yet been well characterized. In this study, whole-mount atria from FVB mice were processed with calcitonin gene-related peptide (CGRP) and substance P (SP) primary antibodies followed by secondary antibodies, and then examined using confocal microscopy. We found: 1) Large CGRP-IR axon bundles entered the atria with the major veins, and these large bundles bifurcated into small bundles and single axons that formed terminal end-nets and free endings in the epicardium. Varicose CGRP-IR axons had close contacts with muscle fibers, and some CGRP-IR axons formed varicosities around principle neurons (PNs) within intrinsic cardiac ganglia (ICGs). 2) SP-IR axons also were found in the same regions of the atria, attached to veins, and within cardiac ganglia. Similar to CGRP-IR axons, these SP-IR axons formed terminal end-nets and free endings in the atrial epicardium and myocardium. Within ICGs, SP-IR axons formed varicose endings around PNs. However, SP-IR nerve fibers were less abundant than CGRP-IR fibers in the atria. 3) None of the PNs were CGRP-IR or SP-IR. 4) CGRP-IR and SP-IR often colocalized in terminal varicosities around PNs. Collectively, our data document the distribution pattern and morphology of CGRP-IR and SP-IR axons and terminals in different regions of the atria. This knowledge provides useful information for CGRP-IR and SP-IR axons that can be referred to in future studies of pathological remodeling.
Autonomic neuroscience : basic & clinical.Auton Neurosci.2014 Apr;181:37-48. doi: 10.1016/j.autneu.2013.12.010. Epub 2013 Dec 23.
The murine model has been used to investigate the role of cardiac sensory axons in various disease states. However, the distribution and morphological structures of cardiac nociceptive axons in normal murine tissues have not yet been well characterized. In this study, whole-mount atria from FVB mice
PMID 24433968

The Aberdeen Varicose Vein Questionnaire May be the Preferred Method of Rationing Patients for Varicose Vein Surgery.

Lattimer CR1, Kalodiki E, Azzam M, Geroulakos G.Author information 11Josef Pflug Vascular Laboratory, Ealing Hospital Middlesex, UK.AbstractRationing treatment of varicose veins (VVs) is of importance in countries with a public health service and limited funds. This study examines why and how the Aberdeen varicose vein questionnaire (AVVQ) can be used in achieving rationing. Baseline assessments prior to endovenous treatment included the venous clinical severity score (VCSS), venous filling index (VFI), and the refluxing great saphenous vein (GSV) diameter. Absolute change in the AVVQ defined improvement. There was no significant correlation in AVVQ improvement compared to baseline VCSS, VFI, GSV diameter or when patients were divided into mild and severe disease (C2,3 vs C4-6) or laser ablation versus foam sclerotherapy. However, AVVQ improvement significantly correlated at 3 weeks (n = 84) and 3 months (n = 70) with their baseline values (r = .5 and r = .585), P < .0005 (Spearman). In conclusion, patients with an initial poor quality of life may benefit most from endovenous treatment, irrespective of other baseline severity assessments.
Angiology.Angiology.2014 Mar;65(3):205-9. doi: 10.1177/0003319712474953. Epub 2013 Jan 31.
Rationing treatment of varicose veins (VVs) is of importance in countries with a public health service and limited funds. This study examines why and how the Aberdeen varicose vein questionnaire (AVVQ) can be used in achieving rationing. Baseline assessments prior to endovenous treatment included th
PMID 23378194

Association between interleukin-10 -1082A/G, -819C/T and -592C/A polymorphisms with deep venous thrombosis.

Tang B1, Chen YK1, Luo WJ1, Fu J1, Sun JM2.Author information 1Department of Vascular Surgery, The Second Affiliated Hospital, Chongqing Medical University, Chongqing 400010, PR China.2Department of Vascular Surgery, The Second Affiliated Hospital, Chongqing Medical University, Chongqing 400010, PR China. Electronic address: jianmingsun@live.cn.AbstractBACKGROUND: Deep venous thrombosis (DVT) and inflammation are two closely related entities. The objective of this study was to evaluate a possible association between interleukin-10 (IL-10) -1082A/G, -819C/T and -592C/A polymorphisms with DVT.
Human immunology.Hum Immunol.2014 Mar;75(3):203-7. doi: 10.1016/j.humimm.2013.12.013. Epub 2013 Dec 27.
BACKGROUND: Deep venous thrombosis (DVT) and inflammation are two closely related entities. The objective of this study was to evaluate a possible association between interleukin-10 (IL-10) -1082A/G, -819C/T and -592C/A polymorphisms with DVT.METHODS: A case-control study was carried out in 660 pati
PMID 24374045

Japanese Journal

カラードプラ超音波検査により診断し得た子宮円索静脈瘤の2例

前岡悦子,山岸宏江,説田政樹,佐藤幸恵,岡田好美,小島祐毅,山田雄一郎,清水由貴,有吉彩,湯浅典博
Japanese journal of medical ultrasonics = 超音波医学 39(4), 471-476, 2012-07-15
NAID 10030811466

Angiokeratoma of the clitoris with evident vulvar varicosity

ULKER Volkan,CAKIR Emel,GEDIKBASI Ali,AKYOL Alpaslan,NUMANOGLU Ceyhun,CULKILIK Ahmet
The journal of obstetrics and gynaecology research 36(6), 1249-1251, 2010-12-01
NAID 10031121779

Flap loop of GluD2 binds to Cbln1 and induces presynaptic differentiation

Kuroyanagi Tomoaki,Hirano Tomoo
Biochemical and biophysical research communications 398(3), 537-541, 2010-07-30
… Finally, a homology model of GluD2-NTD suggested that the flap loop is located at the distal end, which appears consistent with an interaction with Cbln1 and a presynaptic varicosity. …
NAID 120002511328

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