uremic toxins

尿毒症性毒素、尿毒症毒素、uremic toxin

WordNet

1. a poisonous substance produced during the metabolism and growth of certain microorganisms and some higher plant and animal species

PrepTutorEJDIC

1. (特にバクテリアの)毒素

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2016/10/31 09:47:20」(JST)

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[Wiki en表示]

Uremic toxins are toxins accumulating in chronic renal failure patients treated with standard dialysis. These toxins show various cytotoxic activities in the serum, have different molecular weights and some of them are bound to other proteins, primarily to albumin. Such toxic protein bound substances are receiving the attention of scientists who are interested in improving the standard chronic dialysis procedures used today.

References

External links

• EUTox Uremic Toxins Work Group by ESAO Learn more about toxins accumulating in uremic patients

UpToDate Contents

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• 1. 尿毒症毒素 uremic toxins
• 2. 末期腎不全における他の腎代替療法 alternative renal replacement therapies in end stage renal disease
• 3. 尿毒症における血小板機能不全 platelet dysfunction in uremia
• 4. Technical aspects of hemodiafiltration
• 5. 小児における志賀毒素産生性大腸菌（STEC）溶血性尿毒症症候群（HUS）の臨床症状および診断 clinical manifestations and diagnosis of shiga toxin producing escherichia coli stec hemolytic uremic syndrome hus in children

English Journal

• Synbiotics Easing Renal Failure by Improving Gut Microbiology (SYNERGY): A Randomized Trial.

• Rossi M1, Johnson DW2, Morrison M3, Pascoe EM4, Coombes JS5, Forbes JM6, Szeto CC7, McWhinney BC8, Ungerer JP8, Campbell KL2.
• Clinical journal of the American Society of Nephrology : CJASN.Clin J Am Soc Nephrol.2016 Jan 15. pii: CJN.05240515. [Epub ahead of print]
• BACKGROUND AND OBJECTIVES: The generation of key uremic nephrovascular toxins, indoxyl sulfate (IS), and p-cresyl sulfate (PCS), is attributed to the dysbiotic gut microbiota in CKD. The aim of our study was to evaluate whether synbiotic (pre- and probiotic) therapy alters the gut microbiota and red
• PMID 26772193

• Effect of Synbiotic Therapy on Gut-Derived Uremic Toxins and the Intestinal Microbiome in Patients with CKD.

• Vaziri ND1.
• Clinical journal of the American Society of Nephrology : CJASN.Clin J Am Soc Nephrol.2016 Jan 15. pii: CJN.13631215. [Epub ahead of print]
• PMID 26772192

• Analytical and Finite Element Modeling of Nanomembranes for Miniaturized, Continuous Hemodialysis.

• Burgin T1, Johnson D2, Chung H3, Clark A4, McGrath J5.
• Membranes.Membranes (Basel).2015 Dec 31;6(1). pii: E6. doi: 10.3390/membranes6010006.
• Hemodialysis involves large, periodic treatment doses using large-area membranes. If the permeability of dialysis membranes could be increased, it would reduce the necessary dialyzer size and could enable a wearable device that administers a continuous, low dose treatment of chronic kidney disease.
• PMID 26729179

Japanese Journal

• 硫酸抱合型尿毒症物質の肝合成阻害を機軸とする腎保護・尿毒症治療薬の探索

• 細胞 48(3), 142-147, 2016-03
• NAID 40020848126

• Crucial Role of the Aryl Hydrocarbon Receptor (AhR) in Indoxyl Sulfate-Induced Vascular Inflammation

• Ｊｏｕｒｎａｌ　ｏｆ　Ａｔｈｅｒｏｓｃｌｅｒｏｓｉｓ　ａｎｄ　Ｔｈｒｏｍｂｏｓｉｓ 23(8), 960-975, 2016
• NAID 130005254345

• Correlations between Plasma Levels of Anionic Uremic Toxins and Clinical Parameters in Hemodialysis Patients

• 薬学雑誌 136(8), 1177-1184, 2016
• NAID 130005253434

Related Links

• uremic toxins

The topic of the EUTox working group is the identification of yet unknown uremic toxins, the characterisation of uremic toxins and the development of new therapeutic approaches for the treatment of chronic kidney diseases. ...

• Uremic toxins - Evidence-Based Clinical Decision Support at ...

The uremic syndrome can be defined as the deterioration of multiple biochemical and physiological functions in parallel with progressive renal failure, thereby resulting in complex but variable symptomatology. Normally, healthy ...

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関連記事

「uremic」

「uremic」

　　[★]

• adj.

• 尿毒症性の、尿毒症の、尿毒性の、尿毒の

関

uraemia、uraemic、uremia