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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2013/11/22 17:45:01」(JST)

Triethylenemelamine (a.k.a Tretamine) is a drug used in chemotherapy.

It can cause chromatid aberrations in cell models.^[1]

References

^ Luippold HE, Gooch PC, Brewen JG (February 1978). "The production of chromosome aberrations in various mammalian cells by triethylenemelamine". Genetics 88 (2): 317–26. PMC 1213803. PMID 565312.

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Quantitative dose-response curves from subcellular lipid multilayer microarrays.

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Risk of subsequent malignant neoplasms in long-term hereditary retinoblastoma survivors after chemotherapy and radiotherapy.

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Systematic in-vitro evaluation of the NCI/NIH Developmental Therapeutics Program Approved Oncology Drug Set for the identification of a candidate drug repertoire for MLL-rearranged leukemia.

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Radiation- and chemical-induced structural chromosome aberrations in human spermatozoa

上口勇次郎,Kamiguchi Y; Tateno H
MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS 504(1-2), 183-191, 2002-25-Jul
… Chromosome-damaging effects were also found with some chemicals (bleomycin, daunomycin, methyl methanesulfonate, triethylenemelamine, neocarzinostatin, N-methyl-N′-nitro-N-nitorosoguanidine and mitomycin C (MMC)), but not with other chemicals (urethane, nitrobenzene, dioxin, cyclophosphamide (CP), benzo(a)pyrene (BP) and N-nitrosodimethylamine (NDMA)). …
NAID 120001024834

Radiation- and chemical-induced structural chromosome aberrations in human spermatozoa

上口勇次郎,Tateno H
MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS 504(1-2), 183-191, 2002-07
… Chromosome-damaging effects were also found with some chemicals (bleomycin, daunomycin, methyl methanesulfonate, triethylenemelamine, neocarzinostatin, N-methyl-N′-nitro-N-nitorosoguanidine and mitomycin C (MMC)), but not with other chemicals (urethane, nitrobenzene, dioxin, cyclophosphamide (CP), benzo(a)pyrene (BP) and N-nitrosodimethylamine (NDMA)). …
NAID 120003132206

Genotoxic potency in mouse spermatogonial stem cells of triethylenemelamine, mitomycin C, ethylnitrosourea, procarbazine, and propyl methanesulfonate as measured by F1 congenital defects

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