トリエチレンメラミン
- 同
- TEM
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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2013/11/22 17:45:01」(JST)
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Triethylenemelamine
|
Systematic (IUPAC) name |
2,4,6-Tris(aziridin-1-yl)-1,3,5-triazine |
Clinical data |
Pregnancy cat. |
? |
Legal status |
? |
Identifiers |
CAS number |
51-18-3 Y |
ATC code |
None |
PubChem |
CID 5799 |
UNII |
F7IY6HZG9D N |
KEGG |
C07642 N |
ChEMBL |
CHEMBL502384 N |
Chemical data |
Formula |
C9H12N6 |
Mol. mass |
204.23 g/mol |
N (what is this?) (verify)
|
Triethylenemelamine (a.k.a Tretamine) is a drug used in chemotherapy.
It can cause chromatid aberrations in cell models.[1]
See also
References
- ^ Luippold HE, Gooch PC, Brewen JG (February 1978). "The production of chromosome aberrations in various mammalian cells by triethylenemelamine". Genetics 88 (2): 317–26. PMC 1213803. PMID 565312.
English Journal
- Quantitative dose-response curves from subcellular lipid multilayer microarrays.
- Kusi-Appiah AE1, Lowry TW, Darrow EM, Wilson KA, Chadwick BP, Davidson MW, Lenhert S.
- Lab on a chip.Lab Chip.2015 Aug 21;15(16):3397-404. doi: 10.1039/c5lc00478k.
- PMID 26167949
- Risk of subsequent malignant neoplasms in long-term hereditary retinoblastoma survivors after chemotherapy and radiotherapy.
- Wong JR1, Morton LM1, Tucker MA1, Abramson DH1, Seddon JM1, Sampson JN1, Kleinerman RA2.
- Journal of clinical oncology : official journal of the American Society of Clinical Oncology.J Clin Oncol.2014 Oct 10;32(29):3284-90. doi: 10.1200/JCO.2013.54.7844. Epub 2014 Sep 2.
- PMID 25185089
- Systematic in-vitro evaluation of the NCI/NIH Developmental Therapeutics Program Approved Oncology Drug Set for the identification of a candidate drug repertoire for MLL-rearranged leukemia.
- Hoeksema KA1, Jayanthan A, Cooper T, Gore L, Trippett T, Boklan J, Arceci RJ, Narendran A.
- OncoTargets and therapy.Onco Targets Ther.2011;4:149-68. doi: 10.2147/OTT.S21553. Epub 2011 Sep 5.
- PMID 21949608
Japanese Journal
- Radiation- and chemical-induced structural chromosome aberrations in human spermatozoa
- 上口 勇次郎,Kamiguchi Y; Tateno H
- MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS 504(1-2), 183-191, 2002-25-Jul
- … Chromosome-damaging effects were also found with some chemicals (bleomycin, daunomycin, methyl methanesulfonate, triethylenemelamine, neocarzinostatin, N-methyl-N′-nitro-N-nitorosoguanidine and mitomycin C (MMC)), but not with other chemicals (urethane, nitrobenzene, dioxin, cyclophosphamide (CP), benzo(a)pyrene (BP) and N-nitrosodimethylamine (NDMA)). …
- NAID 120001024834
- Radiation- and chemical-induced structural chromosome aberrations in human spermatozoa
- 上口 勇次郎,Tateno H
- MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS 504(1-2), 183-191, 2002-07
- … Chromosome-damaging effects were also found with some chemicals (bleomycin, daunomycin, methyl methanesulfonate, triethylenemelamine, neocarzinostatin, N-methyl-N′-nitro-N-nitorosoguanidine and mitomycin C (MMC)), but not with other chemicals (urethane, nitrobenzene, dioxin, cyclophosphamide (CP), benzo(a)pyrene (BP) and N-nitrosodimethylamine (NDMA)). …
- NAID 120003132206
- Genotoxic potency in mouse spermatogonial stem cells of triethylenemelamine, mitomycin C, ethylnitrosourea, procarbazine, and propyl methanesulfonate as measured by F1 congenital defects
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