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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2014/11/18 19:03:33」(JST)
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Triethylenemelamine
|
Systematic (IUPAC) name |
2,4,6-Tris(aziridin-1-yl)-1,3,5-triazine |
Clinical data |
Legal status |
?
|
Identifiers |
CAS number |
51-18-3 Y |
ATC code |
None |
PubChem |
CID 5799 |
UNII |
F7IY6HZG9D N |
KEGG |
C07642 N |
ChEMBL |
CHEMBL502384 N |
Chemical data |
Formula |
C9H12N6 |
Mol. mass |
204.23 g/mol |
N (what is this?) (verify) |
Triethylenemelamine (a.k.a Tretamine) is a drug used in chemotherapy.
It can cause chromatid aberrations in cell models.[1]
See also
References
- ^ Luippold HE, Gooch PC, Brewen JG (February 1978). "The production of chromosome aberrations in various mammalian cells by triethylenemelamine". Genetics 88 (2): 317–26. PMC 1213803. PMID 565312.
English Journal
- Risk of subsequent malignant neoplasms in long-term hereditary retinoblastoma survivors after chemotherapy and radiotherapy.
- Wong JR1, Morton LM1, Tucker MA1, Abramson DH1, Seddon JM1, Sampson JN1, Kleinerman RA2.
- Journal of clinical oncology : official journal of the American Society of Clinical Oncology.J Clin Oncol.2014 Oct 10;32(29):3284-90. doi: 10.1200/JCO.2013.54.7844. Epub 2014 Sep 2.
- PURPOSE: Hereditary retinoblastoma (Rb) survivors have increased risk of subsequent malignant neoplasms (SMNs). Previous studies reported elevated radiotherapy (RT) -related SMN risks, but less is known about chemotherapy-related risks.PATIENTS AND METHODS: In a long-term follow-up study of 906 5-ye
- PMID 25185089
- Systematic in-vitro evaluation of the NCI/NIH Developmental Therapeutics Program Approved Oncology Drug Set for the identification of a candidate drug repertoire for MLL-rearranged leukemia.
- Hoeksema KA1, Jayanthan A, Cooper T, Gore L, Trippett T, Boklan J, Arceci RJ, Narendran A.
- OncoTargets and therapy.Onco Targets Ther.2011;4:149-68. doi: 10.2147/OTT.S21553. Epub 2011 Sep 5.
- Despite significant progress made in the overall cure rate, the prognosis for relapsed and refractory malignancies in children remains extremely poor. Hence, there is an urgent need for studies that enable the timely selection of appropriate agents for Phase I clinical studies. The Pediatric Oncolog
- PMID 21949608
Related Links
- tretamine an alkylating agent used as an antineoplastic agent; a cause of testicular degeneration. Called also triethylenemelamine. ... Disclaimer All content on this website, including dictionary, thesaurus, literature, geography, and ...
- tretamine [′tred·ə‚mēn] (organic chemistry) triethylenemelamine ... Disclaimer All content on this website, including dictionary, thesaurus, literature, geography, and other reference data is for informational purposes only.
Related Pictures
★リンクテーブル★
[★]
- 英
- triethylenemelamine TEM
- 同
- トレタミン tretamine
- 関
- アルキル化薬
[★]
- 関
- hexamethylmelamine