出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2017/05/16 06:37:00」(JST)
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IUPAC name
2,2,2-Trichloroethanol
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CAS Number
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3D model (Jmol)
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ChEBI |
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ChemSpider |
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ECHA InfoCard | 100.003.701 | ||
IUPHAR/BPS
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InChI
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Properties | |||
Chemical formula
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C2H3Cl3O | ||
Molar mass | 149.40 g/mol | ||
Density | 1.55 g/cm3 | ||
Melting point | 17.8 °C (64.0 °F; 290.9 K) | ||
Boiling point | 151 °C (304 °F; 424 K) | ||
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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2,2,2-Trichloroethanol is an organic compound related to ethanol, except the hydrogen atoms at position 2 are replaced with chlorine atoms. In humans, its pharmacological effects are similar to those of its prodrugs, chloral hydrate and chlorobutanol. It has, historically, been used as a sedative hypnotic.[1] The hypnotic drug triclofos (2,2,2-trichloroethyl phosphate) is metabolized in vivo to 2,2,2-trichloroethanol. Chronic exposure may result in kidney and liver damage.[2]
Derivatives:
Hypnotics/sedatives (N05C)
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See also: Receptor/signaling modulators • GABA receptor modulators
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Glycine receptor modulators
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See also: Receptor/signaling modulators • GABAergics • GHBergics • Glutamatergics
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This sedative-related article is a stub. You can help Wikipedia by expanding it.
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リンク元 | 「トリクロロエタノール」 |
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