関: reticulum trabeculare、trabecular meshwork

WordNet

the second compartment of the stomach of a ruminant (同)second stomach
any fine network (especially one in the body composed of cells or blood vessels)
of or relating to trabeculae (同)trabeculate
rod-shaped structures of fibrous tissue that divide an organ into parts (as in the penis) or stabilize the structure of an organ (as in the spleen)
a small constellation in the southern hemisphere near Dorado and Hydrus

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1. 拡張能障害の細胞学的機序cellular mechanisms of diastolic dysfunction [show details]
…calcium levels during systole and diastole occurs at several sites within the cell . The sarcoplasmic reticulum (SR) plays a central role in regulating contraction and relaxation of mammalian cardiac muscle. …
2. 骨格の正常な発達および骨形成ならびに骨吸収の調節normal skeletal development and regulation of bone formation and resorption [show details]
… which can lead to complete loss of trabecular structures. The resulting perforations and discontinuities convert the normal plate-like trabecular architecture to a much… During rapid phases of bone formation, they may be columnar in shape, with abundant endoplasmic reticulum, and they synthesize collagen rapidly. When bone formation rates are slower, they are flatter and …
3. 骨形成不全症：臨床的特徴および診断osteogenesis imperfecta clinical features and diagnosis [show details]
…mineralization with significant reductions in cortical width, cancellous bone volume, trabecular number, and trabecular width . This study also found significantly increased bone remodeling (turnover) in … binding protein 3-like 1 (CREB3L1), located on chromosome 11p11.2, that encodes an endoplasmic reticulum stress transducer . The variant disrupts a DNA-binding site, preventing it from acting on its transcriptional…
4. 遺伝性ヘモクロマトーシスに伴う関節炎や骨疾患arthritis and bone disease associated with hereditary hemochromatosis [show details]
…microscopy reveals that iron is predominantly found in the lining of cells rich in rough endoplasmic reticulum. Approximately one-half of patients with hereditary hemochromatosis (HH), if untreated, eventually … although the trabecular bone volumes of these two groups were similar in one report .…
5. 正常な加齢normal aging [show details]
… multiple age-related changes from decreased sarcoplasmic reticulum calcium uptake due to alterations of the pump protein (SERCA 2a) ,… The aging loss of mineral occurs in both cortical (peripheral skeleton) and trabecular (axial skeleton) bone.…

English Journal

Prostaglandin EP2 receptor signaling protects human trabecular meshwork cells from apoptosis induced by ER stress through down-regulation of p53.

Kalouche G1, Boucher C2, Coste A3, Debussche L4, Orsini C3, Baudouin C5, Debeir T6, Vigé X3, Rostène W2.
Biochimica et biophysica acta.Biochim Biophys Acta.2016 Sep;1863(9):2322-32. doi: 10.1016/j.bbamcr.2016.06.008. Epub 2016 Jun 17.
E-prostanoid receptor subtype 2 (EP2) agonists are currently under clinical development as hypotensive agents for the treatment of ocular hypertension. However, the effects of EP2 receptor agonists on trabecular meshwork (TM) alterations leading to primary open-angle glaucoma (POAG) are still unknow
PMID 27321910

The role of microfibrillar-associated protein 4 (MFAP4) in the formation and function of splenic compartments during embryonic and adult life.

Milićević NM1, Schmidt F2, Kunz N2, Kalies K2, Milićević Ž1, Schlosser A3, Holmskov U3, Sorensen GL3, Westermann J4.
Cell and tissue research.Cell Tissue Res.2016 Jul;365(1):135-45. doi: 10.1007/s00441-016-2374-1. Epub 2016 Feb 22.
Microfibrillar-associated protein 4 (MFAP4) is an extracellular protein belonging to the fibrinogen-related protein superfamily and is recognized as an integrin ligand with suggested functions in pulmonary and vascular tissue homeostasis. MFAP4 expression in the spleen is increased during infections
PMID 26899386

Targeting the ER-autophagy system in the trabecular meshwork to treat glaucoma.

Stothert AR1, Fontaine SN1, Sabbagh JJ1, Dickey CA2.
Experimental eye research.Exp Eye Res.2016 Mar;144:38-45. doi: 10.1016/j.exer.2015.08.017. Epub 2015 Aug 22.
A major drainage network involved in aqueous humor dynamics is the conventional outflow pathway, which is gated by the trabecular meshwork (TM). The TM acts as a molecular sieve, providing resistance to aqueous outflow, which is responsible for regulating intraocular pressure (IOP). If the TM is dam
PMID 26302411

Japanese Journal

胆嚢管カルチノイドの1例

村川力彦,梅本一史,鈴木友啓,加藤航平,山村喜之,大野耕一
日本臨床外科学会雑誌 76(9), 2289-2292, 2015
症例は61歳，男性．腹痛にて近医を受診，胆石症と診断された．術前精査で，横行結腸肝弯曲部に早期大腸癌を認めたが，内視鏡的切除が困難なため，手術目的で紹介となった．手術は腹腔鏡下結腸右半切除術および胆嚢摘出術を施行した．術中，胆嚢管内に腫瘤を認めたため，腫瘍を含め切除した．切除標本では胆嚢管に14×10mmの黄色調の亜有茎性腫瘍を認めた．病理組織学的検査で腫瘍細胞は核が円形から卵円形を呈し，好酸性顆 …
NAID 130005141933

<b>Histopathological and Immunohistochemical Characteristics of the Progressive Front of Ameloblastoma </b>

Yasuoka Saori,Kato Takao
International Journal of Oral-Medical Sciences 13(3), 110-119, 2015
… plexiform, follicular, basaloid cell, sheet, trabecular and polycystic types, and immunohistochemical and morphometrical comparative studies were performed.<br> … Columnar and stellate-reticulum-like cells of basaloid cell type showed strong positive reaction for VEGF. …
NAID 130005076115

A rare case report of mandibular metastasis of hepatocellular carcinoma: autopsy, immunohistochemical, and ultrastructural examination with literature review

Enokiya Yasunobu,Hashimoto Sadamitsu,Inoue Takashi,Shibahara Takahiko,Shimono Masaki
Oral Medicine & Pathology 12(4), 135-140, 2008
… Ultrastructurally, abundant mitochondria, rough endoplasmic reticulum, lysosome-like granules, ductal structures and intercellular junctional complexes were distinct in the tumor cells. … Microscopically, the tumor cells had trabecular, solid and sarcomatous appearances with severe atypism. …
NAID 130004509510