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WordNet
- a particular branch of scientific knowledge; "the science of genetics" (同)scientific discipline
- of or relating to toxicology (同)toxicologic
PrepTutorEJDIC
- 〈U〉『科学』;(特に)自然科学 / 〈C〉(個々の)科学,学問 / 〈U〉〈C〉(修練を要する)技術,わざ
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- 1. 成人における薬物中毒への一般的アプローチ general approach to drug poisoning in adults
- 2. 第二世代（非定型）抗精神病薬中毒 second generation atypical antipsychotic medication poisoning
- 3. 第一世代（定型）抗精神病剤中毒 first generation typical antipsychotic medication poisoning
- 4. 潜在性毒素曝露を認める小児に対するアプローチ approach to the child with occult toxic exposure
- 5. スルホニル尿素剤中毒 sulfonylurea agent poisoning
English Journal
- Isolation and molecular characterization of Salmonella enterica serovar Enteritidis from poultry house and clinical samples during 2010.
- Mezal EH, Sabol A, Khan MA, Ali N, Stefanova R, Khan AA.Author information Microbiology Division, National Center for Toxicological Research, U.S. Food and Drug Administration, Jefferson, AR 72079, USA; University of Arkansas at Little Rock, Little Rock, AR 72205, USA; University of Thi-Qar, Science of College, Biology of Dept., Thi-Qar, Iraq.AbstractA total of 60 Salmonella enterica serovar (ser.) Enteritidis isolates, 28 from poultry houses and 32 from clinical samples, were isolated during 2010. These isolates were subjected to testing and analyzed for antibiotic resistance, virulence genes, plasmids and plasmid replicon types. To assess genetic diversity, pulsed-field gel electrophoresis (PFGE) fingerprinting, using the XbaI restriction enzyme, Multiple-Locus Variable-Number Tandem Repeat Analysis (MLVA) and plasmid profiles were performed. All isolates from poultry, and 10 out of 32 clinical isolates were sensitive to ampicillin, chloramphenicol, gentamicin, kanamycin, nalidixic acid, sulfisoxazole, streptomycin, and tetracycline. Twenty-one of thirty-two clinical isolates were resistant to ampicillin and tetracycline, and one isolate was resistant to nalidixic acid. PFGE typing of sixty ser. Enteritidis isolates by XbaI resulted in 10-12 bands and grouped into six clusters each with similarity from 95% to 81%. The MLVA analysis of sixty isolates gave 18 allele profiles with the majority of isolates displayed in three groups, and two clinical isolates found to be new in the PulseNet national MLVA database. All isolates were positive for 12 or more of the 17 virulence genes mostly found in S. enterica (spvB, spiA, pagC, msgA, invA, sipB, prgH, spaN, orgA, tolC, iroN, sitC, IpfC, sifA, sopB, and pefA) and negative for one gene (cdtB). All isolates carried a typical 58 kb plasmid, type Inc/FIIA. Three poultry isolates and one clinical isolate carried small plasmids with 3.8, 6, 7.6 and 11.5 kb. Ten of the clinical isolates carried plasmids, with sizes 36 and 38 kb, types IncL/M and IncN, and one isolate carried an 81 kb plasmid, type IncI. Southern hybridization of a plasmid with an Inc/FIIA gene probe hybridized one large 58 kb plasmid in all isolates. Several large and small plasmids from poultry isolates were not typed by our PCR-based method. These results confirmed that PFGE fingerprinting has limited discriminatory power for ser. Enteritidis in both poultry and clinical sources. However, the plasmid and MLVA allele profiles were a useful and important epidemiology tool to discriminate outbreak strains of ser. Enteritidis from poultry and clinical samples.
- Food microbiology.Food Microbiol.2014 Apr;38:67-74. doi: 10.1016/j.fm.2013.08.003. Epub 2013 Aug 27.
- A total of 60 Salmonella enterica serovar (ser.) Enteritidis isolates, 28 from poultry houses and 32 from clinical samples, were isolated during 2010. These isolates were subjected to testing and analyzed for antibiotic resistance, virulence genes, plasmids and plasmid replicon types. To assess gene
- PMID 24290628
- Development and validation of theoretical linear solvation energy relationship models for toxicity prediction to fathead minnow (pimephales promelas).
- Lyakurwa F, Yang X, Li X, Qiao X, Chen J.Author information Key Laboratory of Industrial Ecology and Environmental Engineering (MOE), School of Environmental Science and Technology, Dalian University of Technology, Dalian 116024, China.AbstractThe acute toxicity predictive models are vitally important for the toxicological information used in the ecological risk assessments. In this study, we used Verhaar classification scheme to group compounds into five modes of toxic action. The quantum chemical descriptors that characterize the electron donor-acceptor property of the compounds were introduced into the theoretical linear solvation energy relationship (TLSER) models. The predictive models have relatively larger data sets, which imply that they cover a wide applicability domain (AD). All models were developed following the Organization for Economic Co-operation and Development (OECD) QSAR models development and validation guidelines. The adjusted determination coefficient (Radj(2)) and external explained variance (QEXT(2)) of the models were ranging from 0.707 to 0.903 and 0.660 to 0.858, respectively, indicating high goodness-of-fit, robustness and predictive capacity. The cavity term (McGowans volume) was the most significant descriptor in the models. Moreover, the electron donor-acceptor (E-TLSER) models are comparable to the TLSER models for the toxicity prediction to fathead minnow. Thus, the E-TLSER models developed can be used to predict acute toxicity of new compounds within the AD.
- Chemosphere.Chemosphere.2014 Feb;96:188-94. doi: 10.1016/j.chemosphere.2013.10.039. Epub 2013 Nov 9.
- The acute toxicity predictive models are vitally important for the toxicological information used in the ecological risk assessments. In this study, we used Verhaar classification scheme to group compounds into five modes of toxic action. The quantum chemical descriptors that characterize the electr
- PMID 24216263
- Herbicide impact on non-target plant reproduction: What are the toxicological and ecological implications?
- Boutin C1, Strandberg B2, Carpenter D3, Mathiassen SK4, Thomas PJ5.Author information 1Environment Canada, Science & Technology Branch, 1125 Colonel By Drive, Raven Rd., Carleton University, Ottawa, ON K1A 0H3, Canada. Electronic address: Celine.Boutin@ec.gc.ca.2Aarhus Universitet, Department of Bioscience, Vejlsøvej 25, 8600 Silkeborg, Denmark.3Environment Canada, Science & Technology Branch, 1125 Colonel By Drive, Raven Rd., Carleton University, Ottawa, ON K1A 0H3, Canada. Electronic address: David.Carpenter@ec.gc.ca.4Aarhus Universitet, Department of Agroecology, Forsøgsvej 1, 4200 Slagelse, Denmark.5Environment Canada, Science & Technology Branch, 1125 Colonel By Drive, Raven Rd., Carleton University, Ottawa, ON K1A 0H3, Canada.AbstractDeclining plant diversity and abundance have been widely reported in agro-ecosystems of North America and Europe. Intensive use of herbicides within cropfields and the associated drift in adjacent habitats are partly responsible for this change. The objectives of this work were to quantify the phenological stages of non-target plants in in-situ field situations during herbicide spray and to compare plant susceptibility at different phenological stages. Results demonstrated that a large number of non-target plants had reached reproductive stages during herbicide spray events in woodlots and hedgerows, both in Canada and Denmark where vegetation varies considerably. In addition, delays in flowering and reduced seed production occurred widely on plants sprayed at the seedling stage or at later reproductive periods, with plants sprayed at reproductive stages often exhibiting more sensitivity than those sprayed as seedlings. Ecological risk assessments need to include reproductive endpoints.
- Environmental pollution (Barking, Essex : 1987).Environ Pollut.2014 Feb;185:295-306. doi: 10.1016/j.envpol.2013.10.009. Epub 2013 Dec 5.
- Declining plant diversity and abundance have been widely reported in agro-ecosystems of North America and Europe. Intensive use of herbicides within cropfields and the associated drift in adjacent habitats are partly responsible for this change. The objectives of this work were to quantify the pheno
- PMID 24316067
Japanese Journal
- Effects of four-week feed restriction on toxicological parameters in beagle dogs
- Experimental animals 64(3), 269-280, 2015-07
- NAID 40020532468
- Microfluidic devices for construction of contractile skeletal muscle microtissues(CELL AND TISSUE ENGINEERING)
- Journal of bioscience and bioengineering 119(2), 212-216, 2015-02
- NAID 110009922584
- Investigation of the Safety and Antihyperglycemic Effect of Apios americana Flower Intake as a Food Material in Normal and Diabetic Mice
- Food Science
- NAID 130005099322
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- The Journal of Toxicological Sciences（略称：J. Toxicol. Sci.）は日本トキシコロジー学会が発行し、医薬品、食品添加物、食品汚染物質、環境汚染物質をはじめ様々な物質の毒性とその発現機構、生体応答、安全性評価、分析法など ...
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| リンク元 | 「毒科学」 |
| 関連記事 | 「toxicological」「toxicologic」「science」 |
「毒科学」
「toxicological」
- adj.
- 中毒学的な、毒物学的な、中毒学の、毒物学の、毒性学の、毒科学の
「toxicologic」
- adj.
- 毒物学的な、中毒学的な
「science」
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- sci