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Tiemonium iodide is an antimuscarinic. It is poorly absorbed from the gut. The active moiety is tiemonium, a quaternary ammonium cation.^[1]

References

^ Scoular, I. T.; Monks, Anne; Burgess, C.; Turner, P. (1977). "Human studies on the bioavailability of a quaternary ammonium compound, tiemonium iodide and tiemonium methosulphate". Current Medical Research and Opinion 4 (10): 732–8. doi:10.1185/03007997609112009. PMID 1052164.

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6,7-Difluoro-1,4-dihydro-1-methyl-4-oxo-3-quinolinecarboxylic acid, a newly designed fluorescence enhancement-type derivatizing reagent for amino compounds.

Hirano J, Hamase K, Miyata H, Zaitsu K.SourceGraduate School of Pharmaceutical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan.
Journal of fluorescence.J Fluoresc.2010 Mar;20(2):615-24. doi: 10.1007/s10895-009-0596-2. Epub 2010 Jan 28.
A novel fluorescence enhancement-type derivatizing reagent for amino compounds, 6,7-difluoro-1,4-dihydro-1-methyl-4-oxo-3-quinolinecarboxylic acid (FMQC), was developed. FMQC reacts with aliphatic primary amino compounds to afford strong fluorescent derivatives having high photo-and thermo-stabiliti
PMID 20108029

Direct asymmetric catalytic thienylaluminum addition to ketones: a concise approach to the synthesis of (S)-tiemonium iodide.

Biradar DB, Zhou S, Gau HM.SourceDepartment of Chemistry, National Chung Hsing University, Taichung 402, Taiwan.
Organic letters.Org Lett.2009 Aug 6;11(15):3386-9. doi: 10.1021/ol901193q.
A direct asymmetric addition of a (2-thienyl)aluminum reagent to ketones catalyzed by a titanium catalyst of (S)-BINOL to afford chiral tertiary 2-thienyl alcohols is reported. The catalytic system works excellently for aromatic ketones and for 1-acetylcyclohexene, furnishing products in excellent e
PMID 19588914

Klouz A, Zaïem A, Trabelsi S, Loueslati MH, Lakhal M, Belkahia C.SourceCentre National de Pharmacovigilance, Sis Hôpital Charles Nicolle, Boulevard du 9 Avril 1938, 1006 Tunis-Bab Souika, Tunisia.
Fundamental & clinical pharmacology.Fundam Clin Pharmacol.2007 Dec;21(6):657-8.
Tiemonium, an anti-spasmodic drug, can have adverse effects related to its anti-muscarinic effect. Dyskinesia is described with other anti-cholinergic drugs, but there are no reports of dyskinesia associated with tiemonium. We report a reversible orofacial dyskinesia following tiemonium intake (cont
PMID 18034667

岡田謙司 [他],今井浩達,外川芳子,野崎正勝,鶴見介登,藤村一,長岡俊治
日本薬理学雑誌 80(6), 495-503, 1982
… Effects of tiemonium iodide (tiemonium, 20 μg/kg), mepenzolate bromide (mepenzolate, 20 μg/kg), butylscopolamine bromide (butylscopolamine, 50 μg/kg) and atropine sulfate (atropine, 10 μg/kg) on the colonic motility in dogs were evaluated using a balloon method. … Inhibitory effects of tiemonium on both the normal proximal colonic motility and the accelerating motility induced by neostigmine metylsulfate (neostigmine, 50 μg/kg) were equal to those of butylscopolamine. …
NAID 130000760447

岡直友 [他],和志田裕人
泌尿器科紀要 16(10), 608-618, 1970-10
… Effect of tiemonium iodide (Visceralgine) on normal ureteral contractile activity was studied on 15 human subjects (25 ureters) by means of strain gauge manometer. …
NAID 120002232383

リンク元	「チエモニウム」
拡張検索	「iodide tiemonium」「tiemonium iodide」

Tiemonium iodide
Systematic (IUPAC) name
	4-[3-hydroxy-3-phenyl-3-(2-thienyl)propyl]-4-methylmorpholin-4-ium iodide
Clinical data
AHFS/Drugs.com	International Drug Names
Legal status	?
Identifiers
CAS number	144-12-7
ATC code	A03AB17
PubChem	CID 72142
ChemSpider	65116
UNII	FZ2LZ7U304
KEGG	D01201
Chemical data
Formula	C18H24INO2S
Molecular mass	445.36 g/mol
	SMILES C[N+]1(CCOCC1)CCC(C2=CC=CC=C2)(C3=CC=CS3)O.[I-];
	InChI InChI=1S/C18H24NO2S.HI/c1-19(11-13-21-14-12-19)10-9-18(20,17-8-5-15-22-17)16-6-3-2-4-7-16;/h2-8,15,20H,9-14H2,1H3;1H/q+1;/p-1; Key:IOFXEUZPIIUQAG-UHFFFAOYSA-M ;