- 関
- temperature sensitivity、thermosensitive、thermosensitivity
WordNet
- responsive to physical stimuli; "a mimosas leaves are sensitive to touch"; "a sensitive voltmeter"; "sensitive skin"; "sensitive to light"
- hurting; "the tender spot on his jaw" (同)sore, raw, tender
- being susceptible to the attitudes, feelings, or circumstances of others; "sensitive to the local community and its needs"
- of or pertaining to classified information or matters affecting national security
- the degree of hotness or coldness of a body or environment (corresponding to its molecular activity)
- the somatic sensation of cold or heat
PrepTutorEJDIC
- (五感が)『敏感な』,感じやすい / 物事を非常に気にする,神経過敏な / 感光性の;(器械などが)感度のよい
- 〈C〉〈U〉『温度』,気温 / 〈C〉〈U〉(人・動物の)『体温』 / 《a ~》平常より高い熱,高熱
UpToDate Contents
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English Journal
- Dielectrophoretic immobilisation of antibodies on microelectrode arrays.
- Otto S, Kaletta U, Bier FF, Wenger C, Hölzel R.Author information Fraunhofer Institute for Biomedical Engineering (IBMT), Branch Potsdam-Golm, 14476 Potsdam, Germany. ralph.hoelzel@ibmt.fraunhofer.de.AbstractA silicon based chip device with a regular array of more than 100 000 cylindrical sub-microelectrodes has been developed for the dielectrophoretic (DEP) manipulation of nanoparticles and molecules in solution. It was fabricated by a standard CMOS (complementary metal oxide semiconductor) compatible process. The distribution of the electrical field gradient was calculated to predict the applicability of the setup. Heating due to field application was determined microscopically using a temperature sensitive fluorescent dye. Depending on voltage and frequency, temperature increase was found to be compatible with protein function. Successful field controlled immobilisation of biomolecules from solution was demonstrated with the autofluorescent protein R-phycoerythrin (RPE) and with fluorescently labelled IgG antibodies. Biological activity after DEP application was proven by immobilisation of an anti-RPE antibody and subsequent binding of RPE. These results demonstrate that the developed chip system allows the directed immobilisation of proteins onto microelectrodes by dielectrophoresis without the need for any chemical modification and that protein function is preserved. Being based on standard lithographical methods, further miniaturisation and on-chip integration of electronics towards a multiparameter single cell analysis system appear near at hand.
- Lab on a chip.Lab Chip.2014 Mar 7;14(5):998-1004. doi: 10.1039/c3lc51190a.
- A silicon based chip device with a regular array of more than 100 000 cylindrical sub-microelectrodes has been developed for the dielectrophoretic (DEP) manipulation of nanoparticles and molecules in solution. It was fabricated by a standard CMOS (complementary metal oxide semiconductor) compatibl
- PMID 24441950
- Triggered Release of Doxorubicin from Temperature-Sensitive Poly(N-(2-hydroxypropyl)-methacrylamide mono/dilactate) Grafted Liposomes.
- van Elk M, Deckers R, Oerlemans C, Shi Y, Storm G, Vermonden T, Hennink WE.Author information Department of Pharmaceutics, Utrecht Institute for Pharmaceutical Sciences, Utrecht University , Utrecht, The Netherlands.AbstractThe objective of this study was to design temperature-sensitive liposomes with tunable release characteristics that release their content at an elevated temperature generated by high intensity focused ultrasound (HIFU) exposure. To this end, thermosensitive polymers of N-(2-hydroxypropyl)methacrylamide mono/dilactate of different molecular weights and composition with a cholesterol anchor (chol-pHPMAlac) were synthesized and grafted onto liposomes loaded with doxorubicin (DOX). The liposomes were incubated at different temperatures and their release kinetics were studied. A good correlation between the release-onset temperature of the liposomes and the cloud point (CP) of chol-pHPMAlac was found. However, release took place at significantly higher temperatures than the CP of chol-pHPMAlac, likely at the CP, the dehydration and thus hydrophobicity is insufficient to penetrate and permeabilize the liposomal membrane. Liposomes grafted with chol-pHPMAlac with a CP of 11.5 °C released 89% DOX within 5 min at 42 °C while for the liposomes grafted with a polymer with CP of 25.0 °C, a temperature of 52 °C was needed to obtain the same extent of DOX release. At a fixed copolymer composition, an increase in molecular weight from 6.5 to 14.5 kDa decreased the temperature at which DOX was released with a release-onset temperature from 52 to 42 °C. Liposomes grafted with 5% chol-pHPMAlac exhibited a rapid release to a temperature increase, while at a grafting density of 2 and 10%, the liposomes were less sensitive to an increase in temperature. Sequential release of DOX was obtained by mixing liposomes grafted with chol-pHPMAlac having different CPs. Chol-pHPMAlac grafted liposomes released DOX nearly quantitatively after pulsed wave HIFU. In conclusion, the release of DOX from liposomes grafted with thermosensitive polymers of N-(2-hydroxypropyl)methacrylamide mono/dilactate can be tuned to the characteristics and the grafting density of chol-pHPMAlac, making these liposomes attractive for local drug delivery using hyperthermia.
- Biomacromolecules.Biomacromolecules.2014 Feb 6. [Epub ahead of print]
- The objective of this study was to design temperature-sensitive liposomes with tunable release characteristics that release their content at an elevated temperature generated by high intensity focused ultrasound (HIFU) exposure. To this end, thermosensitive polymers of N-(2-hydroxypropyl)methacrylam
- PMID 24476227
- A genomic perspective to assessing quality of mass-reared SIT flies used in Mediterranean fruit fly (Ceratitis capitata) eradication in California.
- Calla B, Hall B, Hou S, Geib SM.AbstractBACKGROUND: Temperature sensitive lethal (tsl) mutants of the tephritid C. capitata are used extensively in control programs involving sterile insect technique in California. These flies are artificially reared and treated with ionizing radiation to render males sterile for further release en masse into the field to compete with wild males and disrupt establishment of invasive populations. Recent research suggests establishment of C. capitata in California, despite the fact that over 250 million sterile flies are released weekly as part of the state's preventative program. In this project, genome-level quality assessment was performed, measured as expression differences between the Vienna-7 tsl mutants used in SIT programs and wild flies. RNA-seq was performed to provide a genome-wide map of the messenger RNA populations in C. capitata, and to investigate significant expression changes in Vienna-7 mass reared flies.
- BMC genomics.BMC Genomics.2014 Feb 5;15(1):98. [Epub ahead of print]
- BACKGROUND: Temperature sensitive lethal (tsl) mutants of the tephritid C. capitata are used extensively in control programs involving sterile insect technique in California. These flies are artificially reared and treated with ionizing radiation to render males sterile for further release en masse
- PMID 24495485
Japanese Journal
- 圧力・温度の光学的面計測 (特集 最近の計測技術)
- 設計工学 = Journal of Japan Society for Design Engineering : 日本設計工学会誌 51(7), 469-474, 2016-07
- NAID 40020910332
- 210 感温塗料を用いた形状記憶合金表面の温度分布計測(GS2-3 感温塗料・感圧塗料)
- Thermal Imaging Device using Infrared-to-Visible Converter Made of Temperature Sensitive Phosphor
- Journal of photopolymer science and technology 29(3), 409-412, 2016
- NAID 40020874068
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- IATA offers a variety of time & temperature sensitive labels including blank labels and labels with preprinted temperature ranges ... Time & Temperature Sensitive Labels Time & Temperature Sensitive Label (blank) This label is the ...
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- heat-sensitive、temperature sensitivity、temperature-sensitive、thermoreceptive、thermosensitivity、thermosensory
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低温馴化温度感受性変異株ウイルス
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- acutely、alive、sensibility、sensitively、sensitivity、susceptibility、susceptible、tender
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