WordNet
- systematic combining of root and modifying elements into single words
- a compound made artificially by chemical reactions (同)synthetic substance
- involving or of the nature of synthesis (combining separate elements to form a coherent whole) as opposed to analysis; "limnology is essentially a synthetic science composed of elements...that extend well beyond the limits of biology"- P.S.Welch (同)synthetical
- of a proposition whose truth value is determined by observation or facts; "`all men are arrogant is a synthetic proposition" (同)synthetical
- not genuine or natural; "counterfeit rhetoric that flourishes when passions are synthetic"- George Will
PrepTutorEJDIC
- 総合の,統合的な / 合成の,人造の / にせの,作りごとの / (言語が)総合的な(統語的関係を表すのに,独立した語より屈折形を広く用いるもの) / 合成品,人造物
UpToDate Contents
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English Journal
- A Method for Large-Scale Screening of Random Sequence Libraries to Determine the Function of Unstructured Regions from Essential Proteins.
- Millau JF1, Guillemette B2, Gaudreau L3.
- Methods in molecular biology (Clifton, N.J.).Methods Mol Biol.2017;1528:257-275.
- In this chapter we present a method allowing the screening of random sequences to discover essential aspects of unstructured protein regions in yeast. The approach can be applied to any protein with unstructured peptide sequences for which functions are difficult to decipher, for example the N-termi
- PMID 27854027
- DNA-PAINT Super-Resolution Imaging for Nucleic Acid Nanostructures.
- Dai M1,2.
- Methods in molecular biology (Clifton, N.J.).Methods Mol Biol.2017;1500:185-202.
- Far-field super-resolution fluorescence microscopy has allowed observation of biomolecular and synthetic nanoscale systems with features on the nanometre scale, with chemical specificity and multiplexing capability. DNA-PAINT (DNA-based point accumulation for imaging in nanoscale topography) is a su
- PMID 27813009
- Northern Blotting Techniques for Small RNAs.
- Blevins T1.
- Methods in molecular biology (Clifton, N.J.).Methods Mol Biol.2017;1456:141-162.
- Cells have evolved intricate RNA-directed mechanisms that destroy viruses, silence transposons, and regulate gene expression. These nucleic acid surveillance and gene silencing mechanisms rely upon the selective base-pairing of ~19-25 nt small RNAs to complementary RNA targets. This chapter describe
- PMID 27770364
Japanese Journal
- 遺伝子の損傷診断・発現抑制・デリバリーを統合的に機能化する人工核酸の開発
- 中川 治
- 薬学雑誌. 乙号 134(12), 1319-1329, 2014
- … however, there is no crucial tool for oligonucleotide therapeutics at present. … Based on this concept, we have been cooperatively developing these technologies based on organic synthetic chemistry during the past decade. …
- NAID 130004712984
- 機能性人工核酸の創製を目指した新規核酸合成法の開発
- 大窪 章寛,清尾 康志,関根 光雄
- 有機合成化学協会誌 72(8), 899-909, 2014
- … Recently, we developed O-selective phosphorylation named the proton-block method and the activated phosphite method to synthesize modified DNA oligonucleotide having alkaline-labile functional groups. …
- NAID 130004691490
- Synthesis of Conjugated Oligonucleotide in Solution Phase Using Alkyl-chain-soluble Support
- Shoji Takao,Kim Shokaku,Chiba Kazuhiro
- Chemistry Letters 43(8), 1251-1253, 2014
- … Common synthetic methods, however, rely on heterogeneous coupling strategies that often give low yield. … This report describes a new synthetic strategy for conjugated oligonucleotides using an alkyl-chain-soluble support, which allows high-yielding conjugation with various reporter molecules in homogeneous environment. …
- NAID 130004427137
Related Links
- After the completion of the chain assembly, the solid support-bound oligonucleotide is fully protected: ... additional reporter groups may be attached to an oligonucleotide using a variety of post-synthetic ...
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- 英
- synthetic oligonucleotide
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- 合成オリゴヌクレオチド
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- 英
- synthetic oligonucleotide
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- 合成オリゴ
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- 関
- construction、elaboration、syntheses、synthesis、synthesize、synthetically
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オリゴヌクレオチド