WordNet

systematic combining of root and modifying elements into single words
a compound made artificially by chemical reactions (同)synthetic substance
involving or of the nature of synthesis (combining separate elements to form a coherent whole) as opposed to analysis; "limnology is essentially a synthetic science composed of elements...that extend well beyond the limits of biology"- P.S.Welch (同)synthetical
of a proposition whose truth value is determined by observation or facts; "`all men are arrogant is a synthetic proposition" (同)synthetical
not genuine or natural; "counterfeit rhetoric that flourishes when passions are synthetic"- George Will
a general term for female steroid sex hormones that are secreted by the ovary and responsible for typical female sexual characteristics (同)oestrogen

PrepTutorEJDIC

総合の,統合的な / 合成の,人造の / にせの,作りごとの / (言語が)総合的な(統語的関係を表すのに,独立した語より屈折形を広く用いるもの) / 合成品,人造物
エストロゲン(動物の雌を発情させる卵胞ホルモン)(《英》oestrogen)

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Leonurine hydrochloride inhibits osteoclastogenesis and prevents osteoporosis associated with estrogen deficiency by inhibiting the NF-κB and PI3K/Akt signaling pathways.

Yuan FL1, Xu RS1, Jiang DL1, He XL1, Su Q1, Jin C1, Li X1.
Bone.Bone.2015 Jun;75:128-37. doi: 10.1016/j.bone.2015.02.017. Epub 2015 Feb 21.
Osteoclasts, the primary bone resorbing cells, are responsible for destructive bone diseases such as postmenopausal osteoporosis, rheumatoid arthritis, and periodontitis. Many plant-derived traditional medicines that might suppress the formation and/or function of osteoclasts are promising treatment
PMID 25708053

Estrogen mimics induce genes encoding chemical efflux proteins in gram-negative bacteria.

Li X1, Teske S1, Conroy-Ben O2.
Chemosphere.Chemosphere.2015 Jun;128:327-31. doi: 10.1016/j.chemosphere.2015.02.020. Epub 2015 Mar 6.
Escherichia coli and Pseudomonas aeruginosa are gram-negative bacteria found in wastewater and biosolids. Spanning the inner and outer membrane are resistance-nodulation-cell division superfamily (RND) efflux pumps responsible for detoxification of the cell, typically in response to antibiotics and
PMID 25754012

NJK14013, a novel synthetic estrogen receptor-α agonist, exhibits estrogen receptor-independent, tumor cell-specific cytotoxicity.

Kim HI1, Kim T2, Kim JE1, Lee J2, Heo J2, Lee NR1, Kim NJ2, Inn KS1.
International journal of oncology.Int J Oncol.2015 May 12. doi: 10.3892/ijo.2015.3002. [Epub ahead of print]
Estrogens act through interactions with estrogen receptors (ERs) to play diverse roles in various pathophysiological conditions. A number of synthetic selective estrogen receptor modulators (SERMs), such as tamoxifen and raloxifene, have been developed and used to treat ER-related diseases, includin
PMID 25964080

4) 腟壁と膀胱・尿道間の微小交感神経束を温存する合成メッシュ骨盤底再建手術(シンポジウム1:女性ヘルスケア「中高年に対する女性医学の展開」,第64回日本産科婦人科学会・学術講演会)

古山将康
日本産科婦人科學會雜誌 64(10), 2203-2213, 2012-10-01
… Supporting abnormality of a pelvic floor develops pelvic organ prolapse (POP) such as uterine prolapse, cystocele, rectocele, lower urinary tract symptoms through childbirth and estrogen depletion. … Synthetic proline soft mesh was inserted into behind of the vagina. …
NAID 110009518076

p21 and Notch Signalings in the Persistently Altered Vagina Induced by Neonatal Diethylstilbestrol Exposure in Mice

NAKAMURA Takeshi,MIYAGAWA Shinichi,KATSU Yoshinao [他],MIZUTANI Takeshi,SATO Tomomi,TAKEUCHI Takashi,IGUCHI Taisen,OHTA Yasuhiko
Journal of Veterinary Medical Science 74(12), 1589-1595, 2012
… Perinatal exposure to natural and synthetic estrogens including diethylstilbestrol (DES) or estrogenic chemicals induces estrogen-independent persistent proliferation of vaginal epithelium in mice. … To understand the underlying mechanism of the estrogen-independent persistent vaginal changes induced by perinatal DES exposure, we examined global gene expressions in the vaginae of ovariectomized adult mice exposed neonatally to DES using a microarray. …
NAID 130001879705

Cloning and functional characterization of Chondrichthyes, cloudy catshark, Scyliorhinus torazame and whale shark, Rhincodon typus estrogen receptors

Katsu Yoshinao,Kohno Satomi,Narita Haruka,Urushitani Hiroshi,Yamane Koudai,Hara Akihiko,Clauss Tonya M.,Walsh Michael T.,Miyagawa Shinichi,Guillette Louis J.,Iguchi Taisen
General and Comparative Endocrinology 168(3), 496-504, 2010-09-15
… To understand the molecular mechanisms of estrogen actions and to evaluate estrogen receptor ligand interactions in Elasmobranchii, we cloned a single estrogen receptor (ESR) from two shark species, the cloudy catshark (Scyliorhinus torazame) and whale shark (Rhincodon typus) and used an ERE-luciferase reporter assay system to characterize the interaction of these receptors with steroidal and other environmental estrogens. …
NAID 120003326036