The effect of antagonist pretreatment on the signaling properties of the human metabotropic glutamate 1a (hmGlu1a) receptor was examined in stably transfected L929sA cells. Pre-exposure of hmGlu1a receptor-expressing cells to the mGlu1 receptor antagonists (S)-4-carboxy-3-hydroxyphenylglycine and 7-
D2-mediated modulation of N-type calcium currents in rat globus pallidus neurons following dopamine denervation.
Stefani A, Spadoni F, Martorana A, Lavaroni F, Martella G, Sancesario G, Bernardi G.SourceIRCCS Fondazione Santa Lucia, Via Ardeatina 306, 00179 Roma, Italy. stefani@uniroma2.it
The European journal of neuroscience.Eur J Neurosci.2002 Mar;15(5):815-25.
We have studied the effects of dopamine and the D2-like agonist quinpirole on calcium currents of neurons isolated from the striatum and the globus pallidus (GP). Experiments were performed in young adult rats, either in control conditions or following lesion of the nigrostriatal pathway by the unil