Receptor variation and susceptibility to Middle East respiratory syndrome coronavirus infection.
Barlan A1, Zhao J, Sarkar MK, Li K, McCray PB Jr, Perlman S, Gallagher T.
Journal of virology.J Virol.2014 May;88(9):4953-61. doi: 10.1128/JVI.00161-14. Epub 2014 Feb 19.
The Middle East respiratory syndrome coronavirus (MERS-CoV) recently spread from an animal reservoir to infect humans, causing sporadic severe and frequently fatal respiratory disease. Appropriate public health and control measures will require discovery of the zoonotic MERS coronavirus reservoirs.
Inhibitor of apoptosis protein (IAP) antagonists demonstrate divergent immunomodulatory properties in human immune subsets with implications for combination therapy.
Knights AJ1, Fucikova J, Pasam A, Koernig S, Cebon J.
Cancer immunology, immunotherapy : CII.Cancer Immunol Immunother.2013 Feb;62(2):321-35. doi: 10.1007/s00262-012-1342-1. Epub 2012 Aug 26.
Inhibitor of apoptosis proteins (IAPs) are critical in regulating apoptosis resistance in cancer. Antagonists of IAPs, such as LCL161, are in clinical development and show promise as anti-cancer agents for solid and hematological cancers, with preliminary data suggesting they may act as immunomodula
Microtubule inhibitors such as Vinblastine and Paclitaxel are chemotherapy agents that activate the mitotic spindle checkpoint, arresting cells in mitosis and leading to cell death. The pathways that connect mitotic arrest to cell death are not well characterized. We developed a mammalian cell-based
Hypersensitize definition, Photography. to treat (a film or emulsion) so as to increase its speed. See more. Thesaurus Translate Puzzles & Games Word of the Day Blog Slideshows Apps by Dictionary My Account Log Out Log In ...
hy·per·sen·si·tive (hī′pər-sĕn′sĭ-tĭv) adj. Highly or excessively sensitive. hy′per·sen′si·tive·ness, hy′per·sen′si·tiv′i·ty n. hy′per·sen′si·tize′ (-tīz′) v. hypersensitize (ˌhaɪpəˈsɛnsɪˌtaɪz) or hypersensitise vb 1. (Photography) (tr) to treat (a ...