WordNet

a silvery soft waxy metallic element of the alkali metal group; occurs abundantly in natural compounds (especially in salt water); burns with a yellow flame and reacts violently in water; occurs in sea water and in the mineral halite (rock salt) (同)Na, atomic number 11

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AcrA dependency of the AcrD efflux pump in Salmonella enterica serovar Typhimurium.

Yamasaki S, Nagasawa S, Hayashi-Nishino M, Yamaguchi A, Nishino K.SourceLaboratory of Microbiology and Infectious Diseases, Institute of Scientific and Industrial Research, Osaka University, Ibaraki, Osaka, Japan.
The Journal of antibiotics.J Antibiot (Tokyo).2011 Jun;64(6):433-7. doi: 10.1038/ja.2011.28. Epub 2011 Apr 20.
Multidrug efflux pumps belonging to the resistance-nodulation cell division (RND) family have major roles in the intrinsic and elevated resistance of Gram-negative bacteria to a wide range of compounds. RND efflux pumps require two other proteins to function: a membrane fusion protein (MFP) and an o
PMID 21505470

Fukuda M, Sasaki K.SourceDepartment of Ophthalmology, Kanazawa Medical University, Ishikawa, Japan.
Ophthalmic research.Ophthalmic Res.1990;22(2):123-7.
Affinity to melanin and changes of antibacterial activity of melanin-bound drugs were examined in 11 drugs, all of which showed an affinity for melanin. The highest melanin-binding ratio was seen in aminoglycosides. Among these, sisomicin sulfate (SISO) had the highest binding ratio (95.5%). The mel
PMID 2111531

Studies on the Promoting Effects of Carboxylic Acid Derivatives on the Rectal Absorption of β-Lactam Antibiotics in Rats

西村憲一,野崎善弘,吉見彰久,中村正平,北川明子,掛谷宣治,北尾和彦
Chemical & pharmaceutical bulletin 33(1), 282-291, 1985-01-25
… The promoting effects of sodium salts of N-acyl-L-phenylalanines, p-substituted benzoic acids, saturated straight-chain fatty acids, saturated straight-chain α-bromofatty acids and N-acyl-N-methylglycines on the rectal absorption of sodium ampicillin (ABPC Na) were investigated in rats. … The absorption-promoting effect of each carboxylic acid sodium salt was found to be parabolically correlated with its lipo-hydrophilic character (log P). …
NAID 110003625131

寺尾求馬,丸井悦子,米沢誠一,川島儀子
藥學雜誌 102(10), 978-983, 1982-10-25
… The degradation rates of penicillins and cephalospolin C's in aqueous solution were found to be accelerated by the coexistence of sodium bisulfite (SBS). … The destructive actions of SBS on penicillin G, carbenicillin, methicillin and sulbenicillin were shown by comparatively small catalytic rate constants. …
NAID 110003650252