スルベニシリン
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2016/01/13 19:57:01」(JST)
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Sulbenicillin
|
Systematic (IUPAC) name |
(2S,5R,6R)-3,3-dimethyl-7-oxo-6-[(2-phenyl-2-sulfoacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
|
Clinical data |
AHFS/Drugs.com |
International Drug Names |
Identifiers |
CAS Number |
41744-40-5 Y 28002-18-8 |
ATC code |
J01CA16 |
PubChem |
CID: 39031 |
UNII |
Q2VYF0562D N |
KEGG |
D08534 Y |
ChEMBL |
CHEMBL564107 N |
Chemical data |
Formula |
C16H18N2O7S2 |
Molecular mass |
414.45 g/mol |
NY (what is this?) (verify) |
Sulbenicillin (INN) is a penicillin antibiotic.
It has been used in combination with dibekacin.[1]
References
- ^ Aonuma S, Ariji F, Oizumi K, Konno K (June 1987). "Electron microscopy of Pseudomonas aeruginosa treated with sulbenicillin and dibekacin". Tohoku J. Exp. Med. 152 (2): 119–28. doi:10.1620/tjem.152.119. PMID 3114912.
Antibacterials: cell envelope antibiotics (J01C-J01D)
|
|
Intracellular |
- Inhibit peptidoglycan subunit synthesis and transport: NAM synthesis inhibition (Fosfomycin)
- DADAL/AR inhibitors (Cycloserine)
- bactoprenol inhibitors (Bacitracin)
|
|
Glycopeptide |
- Inhibit PG chain elongation: Vancomycin# (Oritavancin
- Telavancin)
- Teicoplanin (Dalbavancin)
- Ramoplanin
|
|
β-lactams/
(Inhibit PBP
cross-links) |
|
|
Other |
- polymyxins/detergent
- depolarizing
- Hydrolyze NAM-NAG
- Gramicidin
- Isoniazid
- Teixobactin
|
|
- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III
Index of bacterial disease
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|
Description |
|
|
Disease |
- Gram-positive firmicutes
- Gram-positive actinobacteria
- Gram-negative proteobacteria
- Gram-negative non-proteobacteria
- Cholera
- Tuberculosis
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|
Treatment |
- Antibiotics
- cell wall
- nucleic acid
- mycobacteria
- protein synthesis
- other
- Antibodies
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|
|
English Journal
- Asymmetric synthesis of allylic sulfonic acids: enantio- and regioselective iridium-catalyzed allylations of Na2SO3.
- Liu W1, Zhao XM, Zhang HB, Zhang L, Zhao MZ.
- Chemistry (Weinheim an der Bergstrasse, Germany).Chemistry.2014 Dec 15;20(51):16873-6. doi: 10.1002/chem.201405058. Epub 2014 Nov 3.
- An enantioselective allylation reaction of allylic carbonates with sodium sulfite (Na2 SO3 ) catalyzed by Ir complex was accomplished, providing allylic sulfonic acids in good to excellent yields with a high level of enantio- and regioselectivities. (R)-2-Phenyl-2-sulfoacetic acid, a key intermediat
- PMID 25367779
- Synthesis of novel hapten and production of generic monoclonal antibody for immunoassay of penicillins residues in milk.
- Jiao SN1, Wang P, Zhao GX, Zhang HC, Liu J, Wang JP.
- Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes.J Environ Sci Health B.2013;48(6):486-94. doi: 10.1080/03601234.2013.761908.
- The objective of this study was to produce a generic monoclonal antibody for determination of penicillins residues in milk. The compound 6-aminopenicillanic acid was used as the template to synthesize two novel generic haptens that were used to produce the monoclonal antibodies. The obtained monoclo
- PMID 23452214
- AcrA dependency of the AcrD efflux pump in Salmonella enterica serovar Typhimurium.
- Yamasaki S1, Nagasawa S, Hayashi-Nishino M, Yamaguchi A, Nishino K.
- The Journal of antibiotics.J Antibiot (Tokyo).2011 Jun;64(6):433-7. doi: 10.1038/ja.2011.28. Epub 2011 Apr 20.
- Multidrug efflux pumps belonging to the resistance-nodulation cell division (RND) family have major roles in the intrinsic and elevated resistance of Gram-negative bacteria to a wide range of compounds. RND efflux pumps require two other proteins to function: a membrane fusion protein (MFP) and an o
- PMID 21505470
Japanese Journal
- 当院における全身麻酔下手術中に使用された抗菌薬の15年間(1992-2006年)の推移
- Ceftazidme耐性Klebsiella pneumoniaeに関する検討
Related Links
- ^Aonuma S, Ariji F, Oizumi K, Konno K (June 1987). "Electron microscopy of Pseudomonas aeruginosa treated with sulbenicillin and dibekacin" ([dead link]). Tohoku J. Exp. Med. 152 (2): 119–28. doi:10.1620/tjem.152.119. PMID 3114912 ...
- 第十六改正日本薬局方 化学薬品等 スルベニシリンナトリウム Sulbenicillin Sodium C16H16N2Na2O7S2 : 458.42 [28002-18-8] 本品は定量するとき,換算した脱水物1 mg 当たり900~ 970μg(力価)を含む.ただし,本品の力価は ...
Related Pictures
![Sulbenicillin ,Kedacillin,Kedacillina](https://1mg.info/0/3/y/1143.jpg)
![http://en.wikipedia.org/wiki/1280](https://1mg.info/0/3/y/1144.jpg)
![나트륨 sulbenicillin sodium 구조 식](https://1mg.info/0/3/y/1145.jpg)
![Sulbenicillin.svg](https://1mg.info/0/3/y/1146.jpg)
![Systematic ( IUPAC ) name](https://1mg.info/0/3/y/1147.jpg)
★リンクテーブル★
[★]
- 英
- sulbenicillin SBPC
- ラ
- sulbenicillinum
- 化
- スルベニシリンナトリウム sulbenicillin sodium
- 同
- スルホベンジルペニシリン ulfobenzyl penicillin SBPC
[★]
スルベニシリン sulbenicillin
[★]
- 関
- sulbenicillin