submucous

• 粘膜下の

関

submucosa、submucosal

WordNet

1. the connective tissue beneath mucous membrane

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2014/06/04 07:06:17」(JST)

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Submucosa
Mucosa Submucosa Meissner's plexus Circular muscle Auerbach's plexus longitudinal muscle Serosa or Adventitia
Endoscopy and radial endoscopic ultrasound images of submucosal tumour in mid-esophagus. The submucosa is seen as a dark ring on the ultrasound image.

In the gastrointestinal tract, the submucosa is the layer of dense irregular connective tissue or loose connective tissue that supports the mucosa, as well as joins the mucosa to the bulk of overlying smooth muscle (fibers running circularly within layer of longitudinal muscle).

Structure

Blood vessels, lymphatic vessels, and nerves (all supplying the mucosa) will run through here. Tiny parasympathetic ganglia are scattered around forming the submucosal plexus (or "Meissner's plexus") where preganglionic parasympathetic neurons synapse with postganglionic nerve fibers that supply the muscularis mucosae. Histologically, the wall of the alimentary canal shows four distinct layers (from the lumen moving out): mucosa, submucosa, muscularis externa, and a serosa or adventitia.

Clinical significance

Identification of the submucosa plays an important role in diagnostic and therapeutic endoscopy, where special fibre-optic cameras are used to perform procedures on the gastrointestinal tract. Abnormalities of the submucosa, such as gastrointestinal stromal tumors, usually show integrity of the mucosal surface.

The submucosa is also identified in endoscopic ultrasound to identify the depth of tumours and to identify other abnormalities. An injection of dye, saline, or epinephrine into the submucosa is imperative in the safe removal of certain polyps.

Endoscopic mucosal resection involves removal of the mucosal layer, and in order to be done safely, a submucosal injection of dye is performed to ensure integrity at the beginning of the procedure.

Small intestinal submucosa

Small intestinal submucosa (SIS) is submucosal tissue in the small intestines of vertebrates. SIS is harvested (typically from pigs) for transplanted structural material in several clinical applications, typically biologic meshes. They have low immunogenicity. Some uses under investigation include a scaffold for intervertebral disc regeneration.

Unlike other scaffold materials, the resorbable SIS extracellular matrix (SIS-ECM) scaffold is replaced by well-organized host tissues, including differentiated skeletal muscle.

Submucosal images

• Stomach.

• Section of the human esophagus. Moderately magnified.

• Vertical section of bladder wall.

• General structure of the gut wall showing the submucosa.

References

External links

• submucosa at eMedicine Dictionary

UpToDate Contents

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English Journal

• Resection of peripheral branches of the posterior nasal nerve compared to conventional posterior neurectomy in severe allergic rhinitis.

• Kobayashi T, Hyodo M, Nakamura K, Komobuchi H, Honda N.SourceDepartment of Otolaryngology, Kochi Medical School, Japan.
• Auris, nasus, larynx.Auris Nasus Larynx.2012 Dec;39(6):593-6. Epub 2012 Feb 15.
• OBJECTIVE: Transnasal resection of the posterior nasal nerve (TRPN) is the surgical procedure for drug therapy-resistant, intractable allergic rhinitis (AR). Submucous inferior turbinectomy also improves nasal symptoms in severe AR. Surgical injury to this peripheral nerve fibre may be the major cau
• PMID 22341334

• Postmenopausal woman with vaginal mass: do not forget to see for uterine inversion.

• Darji P, Banker H, Gandhi V, Thakkar G.SourceDepartment of Radiology, NHL MMC, SCL Hospital, Saraspur, Ahmedabad, Gujarat, India.
• BMJ case reports.BMJ Case Rep.2012 Aug 13;2012. pii: bcr0220125841. doi: 10.1136/bcr-02-2012-5841.
• Inversion of the uterus is a rare clinical problem. It is encountered as an obstetric emergency and is a diagnostic challenge in gynaecology. Non-puerperal inversion usually results from a tumour implanted on fundus of the uterus. Treatment depends on the associated pathology and the stage of the in
• PMID 22891007

Japanese Journal

• 閉塞性睡眠時無呼吸症候群に対する鼻中隔矯正術および下鼻甲介切除術の効果

• 高橋 里沙,大淵 豊明,寳地 信介 [他],竹内 頌子,大久保 淳一,池嵜 祥司,鈴木 秀明
• 日本耳鼻咽喉科学会会報 116(7), 789-792, 2013
• 閉塞性睡眠時無呼吸症候群 (OSAS) において, 鼻腔抵抗はその病態と密接に関与している. 今回われわれはOSASに対する鼻中隔矯正術および粘膜下下鼻甲介骨切除術の効果について検討した.対象は, 鼻中隔彎曲症と肥厚性鼻炎による鼻閉を伴い, 内視鏡下鼻中隔矯正術と両側粘膜下下鼻甲介骨切除術を施行したOSAS患者9例 (男性8例, 女性1例; 平均年齢53.2歳) である. 術前後に終夜睡眠ポリグラ …
• NAID 130003373116

• Office gynecology におけるマイクロ波子宮内膜アブレーションによる粘膜下筋腫の治療

• 津田 晃
• Journal of Microwave Surgery 31(2), 27-31, 2013
• … 　 　The aim of the study is to evaluate the safety and effectiveness of microwave endometrial ablation (MEA) in women with submucous myomas for office-based gynecology. … Thirty outpatients (average age : 44.6 years) who hoped to avoid hysterectomy received MEA for treatment of menorrhagia due to submucous myomas. …
• NAID 130003369254

• 症例報告 ワルファリン療法中に急速に増大・破裂した軟硬口蓋粘膜下血腫の1例

• 桃田 幸弘,茂木 勝美,青田 桂子 [他]
• 日本口腔内科学会雑誌 = Journal of Japanese Society of Oral Medicine 18(2), 68-71, 2012-12
• NAID 40019816737

Related Links

• Submucous - World News

Submucous Fibrosis Treatment by Triamcinolone Acetonide.wmv, Buccal pad of fat flap after Submucous fibrosis re, Inferior Turbinate Submucous Resection Procedure, A.B. - 7 year old with submucous cleft palate

• submucous - definition of submucous in the Medical dictionary ...

submucous /sub·mu·cous/ (sub-mu´kus) beneath a mucous membrane. submucous [-m(y)o o ′kəs] pertaining to a location beneath a mucous membrane. submucosal, adj. submucous [sub-mu´kus] beneath a mucous membrane.

Related Pictures

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★リンクテーブル★

リンク元	「粘膜下」「submucosal」
拡張検索	「submucous window resection of nasal septum」

「粘膜下」

　　[★]

英

submucosa、submucosal、submucous

関

粘膜下層

「submucosal」

　　[★]

• adj.

• 粘膜下の

関

submucosa、submucous

「submucous window resection of nasal septum」

　　[★] 鼻中隔粘膜下窓形切除術