- 関
- STLV-2
WordNet
- a harmful or corrupting agency; "bigotry is a virus that must not be allowed to spread"; "the virus of jealousy is latent in everyone"
- (virology) ultramicroscopic infectious agent that replicates itself only within cells of living hosts; many are pathogenic; a piece of nucleic acid (DNA or RNA) wrapped in a thin coat of protein
- a software program capable of reproducing itself and usually capable of causing great harm to files or other programs on the same computer; "a true virus cannot spread to another computer without human assistance" (同)computer virus
- relating to or resembling an ape; "simian features"
- an ape or monkey
- the 20th letter of the Roman alphabet (同)t
- a tough youth of 1950s and 1960s wearing Edwardian style clothes (同)Teddy boy
PrepTutorEJDIC
- ビールス,ろ過性病原体
- 類人猿の,猿のような / 類人猿,猿
- tritiumの化学記号
UpToDate Contents
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English Journal
- Simian T-lymphotropic Virus-associated lymphoma in 2 naturally infected baboons: T-cell clonal expansion and immune response during tumor development.
- d'Offay JM, Eberle R, Wolf RF, Kosanke SD, Doocy KR, Ayalew S, Mansfeild KG, White GL.Author information Department of Veterinary Pathobiology, Center for Veterinary Health Sciences, Oklahoma State University, Stillwater, Oklahoma, USA. jean.doffay@okstate.eduAbstractTwo young female baboons naturally infected with simian T-lymphotropic virus type 1 (STLV1) were euthanized due to chronic respiratory disease that was unresponsive to treatment. Massive lymphocytic infiltration of the lung interstitium suggested a diagnosis of STLV-associated lymphoma. In each case, the diagnosis was confirmed through inverse PCR (IPCR) that detected monoclonally integrated STLV1 provirus in cellular DNA extracted from lymphoma tissue and peripheral blood cells (PBC). One dominant STLV1-infected T-cell clone and 3 minor clones were detected in PBC from each baboon. Using archived PBC DNA and primers within the proviral genome and chromosomal DNA flanking the STLV1 integration sites in PCR analyses, we determined that the dominant clone in one baboon had first appeared approximately 8 mo after infection and had circulated for 4 y before clinical disease developed. ELISA testing of archived serum revealed that both baboons seroconverted to the p19 and p24 gag proteins and the envelope gp46 protein but not to the viral tax protein. Titers to p24 and gp46 rose significantly after infection and remained relatively constant until death, whereas titers to p19 increased with time. Although spontaneous STLV1-associated lymphomas have been described in baboons, the STLV1-associated lymphomas described here occurred in 2 relatively young baboons, both of whom had become infected with STLV at 3 to 4 y of age and developed lymphoma within 5 y of infection.
- Comparative medicine.Comp Med.2013 Jun;63(3):288-94.
- Two young female baboons naturally infected with simian T-lymphotropic virus type 1 (STLV1) were euthanized due to chronic respiratory disease that was unresponsive to treatment. Massive lymphocytic infiltration of the lung interstitium suggested a diagnosis of STLV-associated lymphoma. In each case
- PMID 23759532
- Simian T-cell lymphotropic virus type I alters the proviral load and biodistribution of simian retrovirus type 2 in co-infected macaques, supporting advancement of immunosuppressive pathology.
- Mitchell JL, Hood S, Mee ET, Wigglesworth E, Sethi M, Auda G, Almond NM, Rose NJ.Author information Divisions of Virology, National Institute for Biological Standards and Control, A Centre of the Health Protection Agency, Blanche Lane, South Mimms, Potters Bar, Hertfordshire, UK. jane.mitchell@nibsc.hpa.org.ukAbstractThe infection dynamics and pathology of a retrovirus may be altered by one or more additional viruses. To investigate this further, this study characterized proviral load, biodistribution and the immune response in Macaca fascicularis naturally infected with combinations of simian retrovirus type 2 (SRV-2) and simian T-cell lymphotropic virus type I (STLV-I). As the mesenteric lymph node (MLN) and the spleen have been implicated previously in response to retroviral infection, the morphology and immunopathology of these tissues were assessed. The data revealed a significant change in SRV-2 biodistribution in macaques infected with STLV-I. Pathological changes were greater in the MLN and spleen of STLV-I-infected and co-infected macaques compared with the other groups. Immune-cell populations in co-infected macaque spleens were increased and there was an atypical distribution of B-cells. These findings suggest that the infection dynamics of each virus in a co-infected individual may be affected to a different extent and that STLV-I appears to be responsible for enhancing the biodistribution and associated pathological changes in SRV-2 in macaques.
- The Journal of general virology.J Gen Virol.2013 Mar;94(Pt 3):623-33. doi: 10.1099/vir.0.046078-0. Epub 2012 Nov 28.
- The infection dynamics and pathology of a retrovirus may be altered by one or more additional viruses. To investigate this further, this study characterized proviral load, biodistribution and the immune response in Macaca fascicularis naturally infected with combinations of simian retrovirus type 2
- PMID 23197576
- HTLV-3/4 and simian foamy retroviruses in humans: discovery, epidemiology, cross-species transmission and molecular virology.
- Gessain A, Rua R, Betsem E, Turpin J, Mahieux R.Author information Institut Pasteur, Unité d'Epidémiologie et Physiopathologie des Virus Oncogènes, France, Département de Virologie, Institut Pasteur, 25-28 rue du Dr Roux, 75724 Paris, Cedex 15, France. agessain@pasteur.frAbstractNon-human primates are considered to be likely sources of viruses that can infect humans and thus pose a significant threat to human population. This is well illustrated by some retroviruses, as the simian immunodeficiency viruses and the simian T lymphotropic viruses, which have the ability to cross-species, adapt to a new host and sometimes spread. This leads to a pandemic situation for HIV-1 or an endemic one for HTLV-1. Here, we present the available data on the discovery, epidemiology, cross-species transmission and molecular virology of the recently discovered HTLV-3 and HTLV-4 deltaretroviruses, as well as the simian foamy retroviruses present in different human populations at risk, especially in central African hunters. We discuss also the natural history in humans of these retroviruses of zoonotic origin (magnitude and geographical distribution, possible inter-human transmission). In Central Africa, the increase of the bushmeat trade during the last decades has opened new possibilities for retroviral emergence in humans, especially in immuno-compromised persons.
- Virology.Virology.2013 Jan 5;435(1):187-99. doi: 10.1016/j.virol.2012.09.035.
- Non-human primates are considered to be likely sources of viruses that can infect humans and thus pose a significant threat to human population. This is well illustrated by some retroviruses, as the simian immunodeficiency viruses and the simian T lymphotropic viruses, which have the ability to cros
- PMID 23217627
Japanese Journal
- Short communication: epidemiological evidence that simian T-lymphotropic virus type 1 in Macaca fuscata has an alternative transmission route to maternal infection.
- Eguchi Katsuyuki,Ohsawa Kazutaka,Fuse Kiyono Mieko,Suzuki Juri,Kurokawa Kenji,Yamamoto Taro
- AIDS Research and Human Retroviruses 27(2), 113-114, 2011-02
- … Serological inspection of Simian T-lymphotropic Virus Type 1 was conducted for a wild colony of Macaca fuscata, which was captured in the middle Honshu, Japan. … This finding suggests that, in contrast with human T-lymphotropic Virus Type 1, horizontal transmission play an important role in increasing prevalence of STLV-1 with age among M. …
- NAID 120003751814
- Non-invasive testing reveals a high prevalence of simian T-lymphotropic virus type 1 antibodies in wild adult chimpanzees of the Tai National Park, Cote d'Ivoire
- Characterization of a new simian T-lymphotropic virus type 1 (STLV-1) in a wild living chimpanzee (Pan troglodytes verus) from Ivory Coast : Evidence of a new STLV-1 group?
Related Links
- "Simian T-lymphotropic virus 2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). ... This graph shows the total number of publications written about "Simian T ...
- Definitions for simian t-lymphotropic virus 2 This page provides all possible meanings and translations of the word simian t-lymphotropic virus 2
Related Pictures
★リンクテーブル★
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- 英
- simian T-lymphotropic virus 2、STLV-2
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- サルT細胞白血病ウイルス2型
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- 英
- simian T-lymphotropic virus 2
- 関
- サルTリンパ球向性ウイルス2
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- 関
- simian T-lymphotropic virus 2
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- 関
- monkey
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ウイルス