WordNet
- a sweetish crystalline amino acid involved in the synthesis by the body of cysteine
- any of various brown and yellow finches of parts of Europe
UpToDate Contents
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English Journal
- Locomotor conditioning by amphetamine requires cyclin-dependent kinase 5 signaling in the nucleus accumbens.
- Singer BF1, Neugebauer NM2, Forneris J2, Rodvelt KR2, Li D2, Bubula N2, Vezina P3.
- Neuropharmacology.Neuropharmacology.2014 Oct;85:243-52. doi: 10.1016/j.neuropharm.2014.05.033. Epub 2014 Jun 2.
- Intermittent systemic exposure to psychostimulants leads to several forms of long-lasting behavioral plasticity including nonassociative sensitization and associative conditioning. In the nucleus accumbens (NAcc), the protein serine/threonine kinase cyclin-dependent kinase 5 (Cdk5) and its phosphory
- PMID 24939858
- Suppression of prolactin signaling by pyrrolidine dithiocarbamate is alleviated by N-acetylcysteine in mammary epithelial cells.
- Wang JH1, Du JY2, Wu YY3, Chen MC2, Huang CH2, Shen HJ2, Lee CF2, Lin TH4, Lee YJ5.
- European journal of pharmacology.Eur J Pharmacol.2014 Sep 5;738:301-9. doi: 10.1016/j.ejphar.2014.05.061. Epub 2014 Jun 18.
- Prolactin is the key hormone to stimulate milk synthesis in mammary epithelial cells. It signals through the Jak2-Stat5 pathway to induce the expression of β-casein, a milk protein which is often used as a marker for mammary differentiation. Here we examined the effect of pyrrolidine dithiocarbamat
- PMID 24952131
- Propofol selectively alters GluA1 AMPA receptor phosphorylation in the hippocampus but not prefrontal cortex in young and aged mice.
- Mao LM1, Hastings JM2, Fibuch EE2, Wang JQ3.
- European journal of pharmacology.Eur J Pharmacol.2014 Sep 5;738:237-44. doi: 10.1016/j.ejphar.2014.05.053. Epub 2014 Jun 4.
- Propofol is a commonly used general anesthetic agent which has been previously shown to enhance the inhibitory GABAergic transmission in the central nervous system. In addition to the GABAergic element, the excitatory transmission may be another central molecular site impacted by propofol. Increasin
- PMID 24907515
Japanese Journal
- A mutation of the fission yeast EB1 overcomes negative regulation by phosphorylation and stabilizes microtubules.
- Iimori Makoto,Ozaki Kanako,Chikashige Yuji,Habu Toshiyuki,Hiraoka Yasushi,Maki Takahisa,Hayashi Ikuko,Obuse Chikashi,Matsumoto Tomohiro
- Experimental cell research 318(3), 262-275, 2012-02-01
- … Mal3 is phosphorylated at a cluster of serine/threonine residues in the linker connecting the CH and EB1-like C-terminal motif domains. … The phosphorylation occurs in a microtubule-dependent manner and reduces the affinity of Mal3 to microtubules. … We propose that because the 89R mutation is resistant to the effect of phosphorylation, it can associate persistently with microtubules and confers a stronger stability of microtubules likely by reinforcing the cylindrical structure. …
- NAID 120003874262
- Lack of Inducible Nitric Oxide Synthase Prevents Lipid-Induced Skeletal Muscle Insulin Resistance Without Attenuating Cytokine Level
- CHA Hye-Na,SONG Seung Eun,KIM Yong-Woon,KIM Jong-Yeon,WON Kyu-Chang,PARK So-Young
- Journal of pharmacological sciences 117(2), 77-86, 2011-10-20
- … In the gastrocnemius, lipid infusion decreased glucose uptake and glycolysis that were accompanied with increased phosphorylation of c-Jun N-terminal kinase and reduced phosphorylation of phosphoinositide 3-kinases and serine/threonine kinase Akt. … However, lipid infusion did not affect glucose uptake or phosphorylation of these proteins in iNOS-knockout mice. …
- NAID 10029896073
Related Links
- Reversible phosphorylation results in a conformational change in the structure in many enzymes and receptors, causing them to become activated or deactivated. Phosphorylation usually occurs on serine, threonine, tyrosine and histidine ...
Related Pictures
★リンクテーブル★
[★]
- 英
- serine phosphorylation
[★]
- 関
- phosphorylate
[★]
セリン
- 関
- L-serine、S、Ser