WordNet

dealing with salacious or indecent material; "a scabrous novel"
of the margin of a leaf shape; having the edge cut or fringed or scalloped
the part of a golf course bordering the fairway where the grass is not cut short
causing or characterized by jolts and irregular movements; "a rough ride" (同)rocky, bumpy, jolty, jolting, jumpy
having or caused by an irregular surface; "trees with rough bark"; "rough ground"; "rough skin"; "rough blankets"; "his unsmooth face" (同)unsmooth
(of persons or behavior) lacking refinement or finesse; "she was a diamond in the rough"; "rough manners"
not perfected; "a rough draft"; "a few rough sketches"

PrepTutorEJDIC

ざらざらした,でこぼこの / わいせつな,きわどい
(表面が)『粗い』,ざらざらした,きめの粗い・でこぼこの / (動きなどが)『荒っぽい』;(空・海などが)荒れた / (人・態度などが)『粗野な』,荒々しい,無作法な / 『おおよその』,あらましの / (ダイヤモンドなど)自然のままの,未加工の / 《話》困難な,つらい,ひどい;(…に)ひどい,むごい《+『on』+『名』》 / (生活が)非文化的な,不便な / 毛深い,毛むくじゃらの,毛が刈ってない / …‘を'乱暴(手荒)に扱う《+『up』+『名,』+『名』+『up』》 / 〈計画・作品など〉‘の'概略を書く,‘を'ざっと下書きする《+『in』(『out』)+『名,』+『名』+『in』(『out』)》 / 〈物の表面など〉‘を'ざらざらにする / 手荒く,乱暴に / 〈U〉《the rough》ラフ(ゴルフのコースで芝をはったフェアウェイ以外の部分) / 〈C〉乱暴者

Scabrous overexpression in the eye affects R3/R4 cell fate specification and inhibits Notch signaling.

Muñoz-Soriano V1,2, Santos D1, Durupt FC2, Casani S1, Paricio N1,2.
Developmental dynamics : an official publication of the American Association of Anatomists.Dev Dyn.2015 Oct 27. doi: 10.1002/dvdy.24362. [Epub ahead of print]
BACKGROUND: Planar cell polarity (PCP) in the Drosophila eye is generated when immature ommatidial preclusters acquire opposite chirality in the dorsal and ventral halves of the eye imaginal disc and rotate 90° towards the equator. The scabrous (sca) gene is involved in R8 differentiation and in th
PMID 26505171

In vitro interaction of emerging contaminants with the cytochrome p450 system of Mediterranean deep-sea fish.

Ribalta C1, Solé M.
Environmental science & technology.Environ Sci Technol.2014 Oct 21;48(20):12327-35. doi: 10.1021/es5029603. Epub 2014 Sep 30.
The interactions of emerging contaminants with the xenobiotic and endogenous metabolizing system of deep-sea fish were compared. The drugs diclofenac, fluoxetine, and gemfibrozil belong to different pharmaceutical classes with diverse mechanistic actions, and the personal care products triclosan, ga
PMID 25225740

Drosophila Tempura, a novel protein prenyltransferase α subunit, regulates notch signaling via Rab1 and Rab11.

Charng WL1, Yamamoto S2, Jaiswal M3, Bayat V4, Xiong B1, Zhang K5, Sandoval H6, David G1, Gibbs S6, Lu HC1, Chen K1, Giagtzoglou N7, Bellen HJ8.
PLoS biology.PLoS Biol.2014 Jan 28;12(1):e1001777. doi: 10.1371/journal.pbio.1001777. eCollection 2014.
Vesicular trafficking plays a key role in tuning the activity of Notch signaling. Here, we describe a novel and conserved Rab geranylgeranyltransferase (RabGGT)-α-like subunit that is required for Notch signaling-mediated lateral inhibition and cell fate determination of external sensory organs. Th
PMID 24492843

canoe encodes a novel protein containing a GLGF/DHR motif and functions with Notch and scabrous in common developmental pathways in Drosophila.

Drosophila eye development: Notch and Delta amplify a neurogenic pattern conferred on the morphogenetic furrow by scabrous.

Homeotic control in Drosophila ; The scabrous gene is an in vivo target of Ultrabithorax proteins