WordNet

the second compartment of the stomach of a ruminant (同)second stomach
any fine network (especially one in the body composed of cells or blood vessels)
a small constellation in the southern hemisphere near Dorado and Hydrus

UpToDate Contents

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1. 拡張能障害の細胞学的機序 cellular mechanisms of diastolic dysfunction
2. 心筋における興奮収縮連関 excitation contraction coupling in myocardium
3. ビタミンKおよびその合成ならびにガンマカルボキシグルタミン酸の機能 vitamin k and the synthesis and function of gamma carboxyglutamic acid
4. ブルセラ菌の微生物学、疫学、および病因 microbiology epidemiology and pathogenesis of brucella
5. ダリエ病 darier disease

English Journal

CHOP mediates XBP1S-induced renal mesangial cell necrosis following high glucose treatment.

Shao D1, Ni J2, Shen Y2, Liu J2, Zhou L2, Xue H2, Huang Y3, Zhang W4, Lu L5.
European journal of pharmacology.Eur J Pharmacol.2015 Jul 5;758:89-96. doi: 10.1016/j.ejphar.2015.03.069. Epub 2015 Apr 6.
High glucose (HG)-induced apoptosis in mesangial cells (MCs) is a critical determinant during the pathogenesis of diabetic nephropathy. The signaling cascade inducing MCs apoptosis by HG involves overproduction of reactive oxygen species. Our previous studies have demonstrated that HG-induced oxidat
PMID 25857226

Anti-diabetic efficacy of KICG1338, a novel glycogen synthase kinase-3β inhibitor, and its molecular characterization in animal models of type 2 diabetes and insulin resistance.

Kim KM1, Lee KS2, Lee GY2, Jin H2, Durrance ES2, Park HS3, Choi SH1, Park KS4, Kim YB5, Jang HC1, Lim S6.
Molecular and cellular endocrinology.Mol Cell Endocrinol.2015 Jul 5;409:1-10. doi: 10.1016/j.mce.2015.03.011. Epub 2015 Mar 20.
Selective inhibition of glycogen synthase kinase-3 (GSK3) has been targeted as a novel therapeutic strategy for diabetes mellitus. We investigated the anti-diabetic efficacy and molecular mechanisms of KICG1338 (2-(4-fluoro-phenyl)-3H-imidazo[4,5-b]pyridine-7-carboxylic acid(4-methyl-pyridin-3-yl)-a
PMID 25802191

Determination of the topology of endoplasmic reticulum membrane proteins using redox-sensitive green-fluorescence protein fusions.

Tsachaki M1, Birk J1, Egert A1, Odermatt A2.
Biochimica et biophysica acta.Biochim Biophys Acta.2015 Jul;1853(7):1672-82. doi: 10.1016/j.bbamcr.2015.04.002. Epub 2015 Apr 15.
Membrane proteins of the endoplasmic reticulum (ER) are involved in a wide array of essential cellular functions. Identification of the topology of membrane proteins can provide significant insight into their mechanisms of action and biological roles. This is particularly important for membrane enzy
PMID 25889538

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