WordNet

impose a blockade on (同)seal off
a war measure that isolates some area of importance to the enemy (同)encirclement
prevents access or progress
obstruct access to (同)block off
a cellular structure that is postulated to exist in order to mediate between a chemical agent that acts on nervous tissue and the physiological response
blocking entrance to and exit from seaports and harbors; "the blockading ships prevented delivery of munitions"

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Chen KH, Xu XH, Liu Y, Hu Y, Jin MW, Li GR.SourceDepartment of Pharmacology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China; Li Ka Shing Faculty of Medicine, Department of Physiology and Medicine, University of Hong Kong, Hong Kong, China.
Journal of cellular physiology.J Cell Physiol.2014 Jan;229(1):60-7. doi: 10.1002/jcp.24417.
Transient receptor potential melastatin-7 (TRPM7) channels are involved in many cellular physiological and pathological processes. The present study was designed to investigate the expression of TRPM7 channels and the potential role in regulating cell proliferation and adipogenesis in 3T3-L1 preadip
PMID 23765921

Dopaminergic D2 receptor is a key player in the substantia nigra pars compacta neuronal activation mediated by REM sleep deprivation.

Proença MB, Dombrowski PA, Da Cunha C, Fischer L, Ferraz AC, Lima MM.SourceLaboratório de Neurofisiologia, Departamento de Fisiologia, Universidade Federal do Paraná, Setor de Ciências Biológicas, Av. Francisco H. dos Santos s/n, 81.531-990, Caixa Postal 19031, Curitiba, PR, Brazil.
Neuropharmacology.Neuropharmacology.2014 Jan;76 Pt A:118-26. doi: 10.1016/j.neuropharm.2013.08.024. Epub 2013 Sep 4.
Currently, several studies addresses the novel link between sleep and dopaminergic neurotransmission, focusing most closely on the mechanisms by which Parkinson's disease (PD) and sleep may be intertwined. Therefore, variations in the activity of afferents during the sleep cycles, either at the leve
PMID 24012539

Targeting EP4 by curcumin through cross talks of AMP-dependent kinase alpha and p38 mitogen-activated protein kinase signaling: The role of PGC-1α and Sp1.

Hann SS, Chen J, Wang Z, Wu J, Zheng F, Zhao S.SourceLaboratory of Tumor Molecular Biology and Targeted Therapies, University of Guangzhou Traditional Chinese Medicine, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou, Guangdong Province, 510120 China. Electronic address: swhan2010@live.com.
Cellular signalling.Cell Signal.2013 Dec;25(12):2566-74. doi: 10.1016/j.cellsig.2013.08.020. Epub 2013 Aug 30.
Head and neck cancer is one of the most morbid human malignancies with an overall poor prognosis and severely compromised quality of life. As a result, there is significant interest in developing adjuvant therapies to augment currently available treatment protocols. Curcumin has been found to posses
PMID 23998949

Pleiotropic Effects of Angiotensin II Receptor Signaling in Cardiovascular Homeostasis and Aging

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International Heart Journal advpub(0), 2015
… Most of the pathophysiological actions of angiotensin II (Ang II) are mediated through the Ang II type 1 (AT1) receptor, a member of the seven-transmembrane G protein-coupled receptor family. … Essentially, AT1 receptor signaling is beneficial for organismal survival and procreation, because it is crucial for normal organ development, and blood pressure and electrolyte homeostasis. …
NAID 130005066389

佐藤哲観,伊藤磨矢,浅利三和子,島田恵子
Palliative Care Research 10(1), 510-514, 2015
【緒言】悪性腸腰筋症候群（以下，MPS）は，悪性腫瘍によって腰神経叢が障害されて生じる腰下肢の痛み，知覚障害，脱力によって特徴づけられ，典型的な神経障害性疼痛を伴い，痛みの緩和に難渋する場合も少なくない．【症例】患者は67歳の女性．左側傍腰椎の悪性リンパ腫により左MPSを生じた．オキシコドンからタペンタドールへのオピオイドスイッチと鎮痛補助薬による薬物療法と腰神経叢ブロックを行って良好な除痛効果を …
NAID 130004943683

Treatment with Anti-Interleukin-6 Receptor Antibody Ameliorates Intestinal Polyposis in ApcMin/+ Mice under High-Fat Diet Conditions

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The Tohoku Journal of Experimental Medicine 235(2), 127-134, 2015
… In the present study, we investigated the effect of IL-6 signaling blockade on intestinal polyp formation in obesity using a mouse model of adenomatous polyposis coli (Apc). … Male C57BL/6J-ApcMin/+ mice were fed a high-fat diet from 5 weeks of age, and the overweight mice thus obtained were given a weekly intraperitoneal injection of anti-mouse IL-6 receptor antibody (MR16-1) from 6 to 15 weeks of age, while control mice received IgG or phosphate-buffered saline (PBS). …
NAID 130004822437