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street name for lysergic acid diethylamide (同)back breaker, battery-acid, dose, dot, Elvis, loony toons, Lucy in the sky with diamonds, pane, superman, window pane, Zen
any of various water-soluble compounds having a sour taste and capable of turning litmus red and reacting with a base to form a salt
having the characteristics of an acid; "an acid reaction"

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酸性の / 酸味のある,すっぱい(sour) / (言葉・態度などが)厳しい,しんらつな / 酸 / すっぱいもの / 《俗》=LSD

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/11/05 04:23:32」(JST)

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Pristanic acid (2,6,10,14-tetramethylpentadecanoic acid) is a terpenoid acid present at micromolar concentrations in the blood plasma of healthy individuals. It is also found in the lipids from many sources such as freshwater sponges, krill, earthworms, whales, human milk fat, bovine depot fat, butterfat or Californian petroleum. It is usually present in combination with phytanic acid. In humans, pristanic acid is obtained from two sources: either directly from the diet or as the alpha oxidation product of phytanic acid. At physiological concentrations pristanic acid is a natural ligand for PPARα. In liver, pristanic acid is degraded by peroxisomal beta oxidation to propionyl-CoA. Together with phytanic acid, pristanic acid accumulates in several inherited disorders such as Zellweger syndrome.

The salts and esters of pristanic acid are called pristanates.

Pristanic acid was first isolated from butterfat by R. P. Hansen and J. D. Morrison in 1964.^[1] The name of the substance is derived from pristane (2,6,10,14-tetramethylpentadecane), the corresponding hydrocarbon. Pristane was isolated from shark liver and was named after Latin pristis, "shark".

References

^ R. P. Hansen, J. D. Morrison, The isolation and identification of 2,6,10,14-tetramethylpentadecanoic acid from butterfat, Biochemical Journal 1964 Nov;93(2):225-8.

UpToDate Contents

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1. 尿酸のバランス uric acid balance
2. ペルオキシソーム病 peroxisomal disorders
3. 出産時の臍帯血酸塩基分析 umbilical cord blood acid base analysis at delivery
4. 妊娠中の葉酸補充 folic acid supplementation in pregnancy
5. ポルフィリン症：概要 porphyrias an overview

English Journal

Rhizomelic Chondrodysplasia Punctata Type 1 Caused by a Novel Mutation in the PEX7 Gene.

Çim A1, Coşkun S, Görükmez O, Yüksel H, Uluca Ü, Pietro ED, Plourde F, Braverman NE.
Journal of clinical research in pediatric endocrinology.J Clin Res Pediatr Endocrinol.2015 Mar 5;7(1):69-72. doi: 10.4274/jcrpe.1835.
Peroxisomes are involved in various metabolic reactions. Rhizomelic chondrodysplasia punctata (RCDP) type 1 is one of the peroxisomal biogenesis disorders caused by mutations in the PEX7 gene and is inherited in an autosomal recessive manner. We present a nine-year-old boy with skeletal abnormalitie
PMID 25800479

A novel bile acid biosynthesis defect due to a deficiency of peroxisomal ABCD3.

Ferdinandusse S1, Jimenez-Sanchez G2, Koster J3, Denis S3, Van Roermund CW3, Silva-Zolezzi I4, Moser AB5, Visser WF3, Gulluoglu M6, Durmaz O7, Demirkol M8, Waterham HR3, Gökcay G8, Wanders RJ3, Valle D2.
Human molecular genetics.Hum Mol Genet.2015 Jan 15;24(2):361-70. doi: 10.1093/hmg/ddu448. Epub 2014 Aug 28.
ABCD3 is one of three ATP-binding cassette (ABC) transporters present in the peroxisomal membrane catalyzing ATP-dependent transport of substrates for metabolic pathways localized in peroxisomes. So far, the precise function of ABCD3 is not known. Here, we report the identification of the first pati
PMID 25168382

Serum phytanic and pristanic acid levels and prostate cancer risk in Finnish smokers.

Wright ME1, Albanes D, Moser AB, Weinstein SJ, Snyder K, Männistö S, Gann PH.
Cancer medicine.Cancer Med.2014 Dec;3(6):1562-9. doi: 10.1002/cam4.319. Epub 2014 Aug 16.
Phytanic acid is a saturated branched-chain fatty acid found predominantly in red meat and dairy products, and may contribute to the elevated risks of prostate cancer associated with higher consumption of these foods. Pristanic acid is formed during peroxisomal oxidation of phytanic acid, and is the
PMID 25132681

Japanese Journal

礼文島浜中２遺跡出土土器を用いた古食性復元

日本地球化学会年会要旨集 58(0), 300-300, 2011
NAID 130005054331

Rapid stable isotope dilution analysis of very-long-chain fatty acids, pristanic acid and phytanic acid using gas chromatography-electron impact mass spectrometry

Journal of chromatography. B, Biomedical sciences and applications 713(2), 281-287, 1998-08-25
NAID 10024530211

Pristanic acid and phytanic acid in plasma from patients with single peroxisomal enzyme deficiency

J. Inher. Mebat. Dis. 14, 345-348, 1991
NAID 30012221098

「プリスタン酸」

Pristanic acid
Names
	IUPAC name 2,6,10,14-tetramethylpentadecanoic acid
Identifiers
CAS Registry Number	1189-37-3
ChEBI	CHEBI:51340
ChemSpider	110458
	InChI InChI=1S/C19H38O2/c1-15(2)9-6-10-16(3)11-7-12-17(4)13-8-14-18(5)19(20)21/h15-18H,6-14H2,1-5H3,(H,20,21) ; Key: PAHGJZDQXIOYTH-UHFFFAOYSA-N ; InChI=1/C19H38O2/c1-15(2)9-6-10-16(3)11-7-12-17(4)13-8-14-18(5)19(20)21/h15-18H,6-14H2,1-5H3,(H,20,21); Key: PAHGJZDQXIOYTH-UHFFFAOYAH ;
Jmol-3D images	Image
PubChem	123929
	SMILES O=C(O)C(CCCC(CCCC(C)CCCC(C)C)C)C ;
Properties
Chemical formula	C19H38O2
Molar mass	298.504
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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	Infobox references

　　[★]

英: pristanate, pristanic acid
同: 2,6,10,14-テトラメチルペンタデカン酸
関: フィタン酸、レフサム症候群

[1] R. P. Hansen, J. D. Morrison, The isolation and identification of 2,6,10,14-tetramethylpentadecanoic acid from butterfat, Biochemical Journal 1964 Nov;93(2):225-8.

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pristanic acid