コーン孔
WordNet
- any tiny hole admitting passage of a liquid (fluid or gas)
- any small opening in the skin or outer surface of an animal
PrepTutorEJDIC
- 《所有・所属》…『の』,…のものである,…に属する・《材料・要素》…『でできた』,から成る・《部分》…『の』[『中の』] ・《数量・単位・種類を表す名詞に付いて》…の・《原因・動機》…『で』,のために(because of) ・《主格関係》…『の』,による,によって・《目的格関係》…『を』,の・《同格関係》…『という』・《関係・関連》…『についての』[『の』],の点で・《抽象名詞などと共に》…の[性質をもつ] ・《『It is』+『形』+『of』+『名』+『to』 doの形で,ofの後の名詞を意味上の主語として》・《分離》…『から』・《起原・出所》…『から』[『の』](out of) ・《『名』+『of』+『a』(『an』)+『名』の形で》…のような・《『名』+『of』+『mine』(『yours, his』など独立所有格)の形で》…の…・《時》(1)《副詞句を作って》…に《形容詞句を作って》…の・《時刻》《米》…前(to,《米》before)
- 《pore over+名》(…を)熟読する,注意深く考える・没頭する, 熟考［熟視，熟読］する
- 気孔,毛穴
- OLD French古[代]フランス語
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/09/11 18:29:15」(JST)
[Wiki en表示]
The Pores of Kohn (also known as interalveolar connections) are discrete holes in walls of adjacent alveoli.[1] Cuboidal type II alveolar cell usually forms part of aperture.[2]
Contents
- 1 Etymology
- 2 Development
- 3 Function
- 4 References
Etymology
The Pores of Kohn take their name from the German physician Hans Kohn [1866-1935] who first described them in 1893.[3]
Development
They are absent in human newborns. They develop at 3-4 years of age along with Canals of Lambert during process of thinning of alveolar septa.[4][2]
Function
They function as a means of collateral ventilation; that is, if the lung is partially deflated, ventilation can occur to some extent through these pores. They also allow air to pass through, this provides collateral ventilation and even distribution of air to the alveoli. They equalize the pressure in adjacent alveoli and thus play important role in prevention of collapse of lung.[5] The pores also allow the passage of other materials such as fluid and bacteria, which is an important mechanism of spread of infection in Lobar pneumonia and spread of fibrin in grey hepatisation phase of recovery from the same.
References
- ^ Desplechain C, Foliguet B, Barrat E, Grignon G, Touati F; Foliguet; Barrat; Grignon; Touati (1983). "[The pores of Kohn in pulmonary alveoli]". Bull Eur Physiopathol Respir 19 (1): 59–68. PMID 6850150.
- ^ a b Miller, J.E. Cotes, D.J. Chinn, M.R. (2006). Lung function : theory and measurement in health and disease (6th ed.). Malden, Mass.: Blackwell Pub. p. 27. ISBN 978-0-632-06493-9.
- ^ H.N. Kohn: “Zur Histologie der indurierenden fibrinösen Pneumonie”. Münchener Medicinische Wochenschrift 1893 40: 42-45
- ^ Paediatric pulmonary function testing : 41 tables ([Online-Ausg.] ed.). Basel [u.a.]: Karger. 2005. p. 6. ISBN 3-8055-7753-2.
- ^ Clinical Procedures In Emergency Medicine & Color Atlas Of Emergency Department Procedures. W B Saunders Co. 2005. p. 149. ISBN 1416022503.
UpToDate Contents
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English Journal
- Case of round pneumonia: pulmonary infarct and a rare situation that is similar with the lung cancer.
- Cimen D1, Bulcun E, Ekici A, Güngör O, Ekici M.
- The clinical respiratory journal.Clin Respir J.2014 Apr 14. doi: 10.1111/crj.12137. [Epub ahead of print]
- BACKGROUND AND AIMS: Round pneumonia (RP) is a rare radiological presentation of a subtype of lobar pneumonia that arises because of a developmental defect in connective tissues (pores of Köhn and channels of Lambert). The round appearance on chest X-ray (CXR) is thought to occur from an infectious
- PMID 24725533
- Defeating the pores of Kohn.
- Ng CS1, Lau RW, Lau KK, Underwood MJ, Yim AP.
- Asian cardiovascular & thoracic annals.Asian Cardiovasc Thorac Ann.2014 Jan;22(1):102-4. doi: 10.1177/0218492312474454.
- In the treatment of emphysema with an endobronchial valve, entire lobar treatment is important in achieving adequate atelectasis. This case illustrates that without treatment of the entire lobe, it can fail to collapse even after several years, leading to treatment failure. Intralobar collateral ven
- PMID 24585656
- Agent-based model of human alveoli predicts chemotactic signaling by epithelial cells during early Aspergillus fumigatus infection.
- Pollmächer J1, Figge MT1.
- PloS one.PLoS One.2014 Oct 31;9(10):e111630. doi: 10.1371/journal.pone.0111630. eCollection 2014.
- Aspergillus fumigatus is one of the most important human fungal pathogens, causing life-threatening diseases. Since humans inhale hundreds to thousands of fungal conidia every day, the lower respiratory tract is the primary site of infection. Current interaction networks of the innate immune respons
- PMID 25360787
Japanese Journal
- Breakdown of lung framework and an increase in pores of Kohn as initial events of emphysema and a cause of reduction in diffusing capacity
- 呼吸器感染症の臨床・画像診断画像所見による起炎菌の推定と治療
- 経過中に鏡面形成を呈したBronchial Atresiaの1例
Related Links
- It is further postulated that pores may be divided by a capillary column stretching across the space, resulting in two openings. A type II alveolar cell forming part of the pore wall may straddle the capillary column. Alveolar macrophages may be found lying free in the pore or lying astride a capillary column.
- Pores of Kohn are small communications between adjacent pulmonary alveoli and provide a collateral pathway for aeration. They are poorly formed in children and along with poorly formed canals of Lambert, are thought to be responsible for the frequency of round pneumonia in that age group. They are typically less than 10 micrometers in diameter 1.
- Thehistory of the investigations into interalveolarcommunications (pores ofKohn)showsthatthe question whetherthey exist and,if so, their nature has for approximately a century beencontentious. Thepresent electron microscopic study ofthe lungsof mice demonstrates thatalveolar pores are normalstructures, with edges composed of intact alveolar wall.Anumberofplanes aredemonstratedfromw-hicha fullycompatiblereconstructionismade.It isconcludedthat pores are round or oval structures frequently havingat least one type
★リンクテーブル★
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- 英
- pore of Kohn, pores of Kohn, alveolar pore of Kohn, Kohn's pore, Kohn pore
- 同
- 肺胞孔、コーンの孔
- 関
- 側副換気、ランバート管、気管支、肺
- 肺胞同士の交通路。普段は閉じているが、閉塞などにより生じた肺胞間の圧較差で開放し、コーン孔を通じて換気されるようになる。
- the alveolar walls are not solid but are perforated by numerous pores of Kohn (BPT.480)
- この孔を通ってバクテリアや浸出液が肺胞間を通過しうる