コーン孔
WordNet
- any tiny hole admitting passage of a liquid (fluid or gas)
- any small opening in the skin or outer surface of an animal
PrepTutorEJDIC
- 《所有・所属》…『の』,…のものである,…に属する・《材料・要素》…『でできた』,から成る・《部分》…『の』[『中の』] ・《数量・単位・種類を表す名詞に付いて》…の・《原因・動機》…『で』,のために(because of) ・《主格関係》…『の』,による,によって・《目的格関係》…『を』,の・《同格関係》…『という』・《関係・関連》…『についての』[『の』],の点で・《抽象名詞などと共に》…の[性質をもつ] ・《『It is』+『形』+『of』+『名』+『to』 doの形で,ofの後の名詞を意味上の主語として》・《分離》…『から』・《起原・出所》…『から』[『の』](out of) ・《『名』+『of』+『a』(『an』)+『名』の形で》…のような・《『名』+『of』+『mine』(『yours, his』など独立所有格)の形で》…の…・《時》(1)《副詞句を作って》…に《形容詞句を作って》…の・《時刻》《米》…前(to,《米》before)
- 《pore over+名》(…を)熟読する,注意深く考える・没頭する, 熟考［熟視，熟読］する
- 気孔,毛穴
- OLD French古[代]フランス語
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/10/15 11:34:35」(JST)
[Wiki en表示]
The Pores of Kohn (also known as interalveolar connections) are discrete holes in walls of adjacent alveoli.[1] Cuboidal type II alveolar cell usually forms part of aperture.[2]
Contents
- 1 Etymology
- 2 Development
- 3 Function
- 4 References
Etymology
The Pores of Kohn take their name from the German physician Hans Kohn [1866-1935] who first described them in 1893.[3]
Development
They are absent in human newborns. They develop at 3-4 years of age along with Canals of Lambert during process of thinning of alveolar septa.[4][2]
Function
They function as a means of collateral ventilation; that is, if the lung is partially deflated, ventilation can occur to some extent through these pores. They also allow air to pass through, this provides collateral ventilation and even distribution of air to the alveoli. They equalize the pressure in adjacent alveoli and thus play important role in prevention of collapse of lung.[5] The pores also allow the passage of other materials such as fluid and bacteria, which is an important mechanism of spread of infection in Lobar pneumonia and spread of fibrin in grey hepatisation phase of recovery from the same.
References
- ^ Desplechain C, Foliguet B, Barrat E, Grignon G, Touati F; Foliguet; Barrat; Grignon; Touati (1983). "[The pores of Kohn in pulmonary alveoli]". Bull Eur Physiopathol Respir 19 (1): 59–68. PMID 6850150.
- ^ a b Miller, J.E. Cotes, D.J. Chinn, M.R. (2006). Lung function : theory and measurement in health and disease (6th ed.). Malden, Mass.: Blackwell Pub. p. 27. ISBN 978-0-632-06493-9.
- ^ H.N. Kohn: “Zur Histologie der indurierenden fibrinösen Pneumonie”. Münchener Medicinische Wochenschrift 1893 40: 42-45
- ^ Paediatric pulmonary function testing : 41 tables ([Online-Ausg.] ed.). Basel [u.a.]: Karger. 2005. p. 6. ISBN 3-8055-7753-2.
- ^ Clinical Procedures In Emergency Medicine & Color Atlas Of Emergency Department Procedures. W B Saunders Co. 2005. p. 149. ISBN 1416022503.
UpToDate Contents
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- 1. 無気肺：成人における種類および病因atelectasis types and pathogenesis in adults [show details]
…consequence of collateral ventilation between segments within a lobe. Collateral ventilation occurs via three distinct channels (the pores of Kohn, canals of Lambert, and fenestrations of Boren) and all of …
- 2. 小児における無気肺atelectasis in children [show details]
…because their lungs lack the collateral ventilation of adults. Specifically, the lungs of children do not have pores of Kohn and canals of Lambert, which allow collateral ventilation of obstructed alveoli. Thus…
- 3. 特発性器質化肺炎cryptogenic organizing pneumonia [show details]
…Intraluminal plugs of granulation tissue may extend from one alveolus to the adjacent one through the pores of Kohn, giving rise to the characteristic "butterfly" pattern . It is thought that bronchiolar…
- 4. 肺気腫への肺容量減量術bronchoscopic treatment of emphysema [show details]
…the Chartis System, has been developed for bronchoscopic assessment of collateral ventilation, as absence of collateral ventilation improves the likelihood of resorption atelectasis following EBV placement …
- 5. 成人の肺胞胸膜瘻および難治性エアリークalveolopleural fistula and prolonged air leak in adults [show details]
…26 patients included 16 patients without collateral ventilation and 10 patients with collateral ventilation. Of the 16 patients without collateral ventilation, 14 had complete resolution of the PAL with …
English Journal
- Influence of the three-dimensional culture of human bone marrow mesenchymal stromal cells within a macroporous polysaccharides scaffold on Pannexin 1 and Pannexin 3.
- Guerrero J1,2, Oliveira H1, Aid R3, Bareille R1, Siadous R1, Letourneur D3, Mao Y4, Kohn J4, Amédée J1.
- Journal of tissue engineering and regenerative medicine.J Tissue Eng Regen Med.2018 Apr;12(4):e1936-e1949. doi: 10.1002/term.2625. Epub 2018 Jan 8.
- PMID 29222846
- Development of hybrid scaffolds with natural extracellular matrix deposited within synthetic polymeric fibers.
- Goyal R1, Vega ME2, Pastino AK2, Singh S2, Guvendiren M1,3, Kohn J1, Murthy NS1, Schwarzbauer JE2.
- Journal of biomedical materials research. Part A.J Biomed Mater Res A.2017 Aug;105(8):2162-2170. doi: 10.1002/jbm.a.36078. Epub 2017 Apr 19.
- PMID 28371271
- Fibrin glue as a stabilization strategy in peripheral nerve repair when using porous nerve guidance conduits.
- Bhatnagar D1, Bushman JS1,2, Murthy NS1, Merolli A1, Kaplan HM1, Kohn J3.
- Journal of materials science. Materials in medicine.J Mater Sci Mater Med.2017 May;28(5):79. doi: 10.1007/s10856-017-5889-4. Epub 2017 Apr 7.
- PMID 28389905
Japanese Journal
- 経過中に鏡面形成を呈したBronchial Atresiaの1例
- ウサギ新生仔肺におけるＫｏｈｎ孔（中隔孔）の形成機序
Related Links
- Pores of Kohn are small communications between adjacent pulmonary alveoli and provide a collateral pathway for aeration. They are poorly formed in children and along with poorly formed canals of Lambert, are thought to be responsible for the frequency of round pneumonia in that age group. ...
- Journal of Breath Research NOTE Pores of Kohn: forgotten alveolar structures and potential source of aerosols in exhaled breath To cite this article: Michael J Oldham and Owen R Moss 2019 J. Breath Res. 13 021003 View the
- The relation between stretching of alveolar surface (A/A 0) and initiation of pore of Kohn opening is predicted by introducing change in pore radius (r/r 0) and tissue thickness (T/T 0) into Lu's calculations [].
★リンクテーブル★
[★]
- 英
- pore of Kohn, pores of Kohn, alveolar pore of Kohn, Kohn's pore, Kohn pore
- 同
- 肺胞孔、コーンの孔
- 関
- 側副換気、ランバート管、気管支、肺
- 肺胞同士の交通路。普段は閉じているが、閉塞などにより生じた肺胞間の圧較差で開放し、コーン孔を通じて換気されるようになる。
- the alveolar walls are not solid but are perforated by numerous pores of Kohn (BPT.480)
- この孔を通ってバクテリアや浸出液が肺胞間を通過しうる