Reprogramming epigenetic modifications to cytosine is required for normal embryo development. We used improved immunolocalization techniques to simultaneously map global changes in the levels of 5'-methylcytosine (5meC) and 5'-hydroxymethylcytosine (5hmC) in each cell of the embryo from fertilizatio
New memory devices based on the proton transfer process.
Wierzbowska M1.
Nanotechnology.Nanotechnology.2016 Jan 8;27(1):015202. doi: 10.1088/0957-4484/27/1/015202. Epub 2015 Nov 24.
Memory devices operating due to the fast proton transfer (PT) process are proposed by the means of first-principles calculations. Writing information is performed using the electrostatic potential of scanning tunneling microscopy (STM). Reading information is based on the effect of the local magne
Denosumab-treated Giant Cell Tumor of Bone Exhibits Morphologic Overlap With Malignant Giant Cell Tumor of Bone.
Wojcik J1, Rosenberg AE, Bredella MA, Choy E, Hornicek FJ, Nielsen GP, Deshpande V.
The American journal of surgical pathology.Am J Surg Pathol.2016 Jan;40(1):72-80. doi: 10.1097/PAS.0000000000000506.
Giant cell tumor (GCT) of bone is a locally aggressive benign neoplasm characterized by an abundance of osteoclastic giant cells that are induced by the neoplastic mononuclear cells; the latter express high levels of receptor activator of nuclear factor κ-B ligand (RANKL). Denosumab, a RANKL inhibi
THE EFFECTS OF CYCLOSPORIN A ON THE POLYKARYOCYTE FORMATION INDUCED BY MEASLES VIRUS IN A MONKEY KIDNEY CELL LINE
渡理 英二,横室 公三
Japanese Journal of Medical Science and Biology 50(2), 79-85, 1997
… The effects of cyclosporin A (CsA) on the polykaryocyte formation induced by measles virus (MV) in a monkey kidney cell line (BSC-1) were studied. … CsA inhibited virus-induced polykaryocyte formation as well as the production of infectious MV. … The development of polykaryocyte formation in the presence of the CsA varied with virus strains, while pretreatment of the cells with 5 μM CsA for 24 hr before the virus infection enhanced polykaryocyte formation. …
pol·y·kar·y·o·cyte (pol'ē-kar'ē-ō-sīt), A cell containing many nuclei, such as the osteoclast. [poly- + G. karyon, kernel, + kytos, cell] polykaryocyte (pŏl″ē-kăr′ē-ō-sīt) [″ + karyon, nucleus, + kytos, cell] A cell possessing several nuclei.
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