poikilocytosis

変形赤血球症

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2016/07/17 04:56:53」(JST)

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Poikilocytosis
Acanthocytosis is one form of poikilocytosis
Classification and external resources
ICD-10	R71
ICD-9-CM	790.09
DiseasesDB	10207

Poikilocytosis refers to the presence of poikilocytes in the blood. Poikilocytes are abnormally shaped red blood cells as seen on a blood film in humans and many wild and domestic species of animals, though they are common in some clinically normal small ruminants, particularly goats.

Normal red blood cells are round, flattened disks that are thinner in the middle than at the edges. A poikilocyte is an abnormally shaped cell. Generally, poikilocytosis can refer to an increase in abnormal red blood cells of any shape where they make up 10% or more of the total population.

Types

Human red blood cells showing poikilocytosis

Membrane abnormalities

1. Acanthocytes or Spur/Spike cells
2. Codocytes or Target cells
3. Echinocytes and Burr cells
4. Elliptocytes and Ovalocytes
5. Spherocytes
6. Stomatocytes or Mouth cells
7. Drepanocytes or Sickle Cells
8. Degmacytes or "bite cells"

Trauma

1. Dacrocytes or Teardrop Cells
2. Keratocytes
3. Microspherocytes and Pyropoikilocytes
4. Schistocytes
5. Semilunar bodies

Treatment

In all cases, the treatment of poikilocytosis depends on its cause. For example, poikilocytosis can be caused by a vitamin deficiency (e.g. vitamin B₁₂ or folic acid), in which case the treatment is to replenish the deficient vitamin. It can be caused by a digestive disease, such as celiac disease, in which case the solution may lie in treating the underlying celiac disease so that nutrients can be properly absorbed.

Etymology

The term derives from poikilos (ποικίλος), which means "varied" in Ancient Greek.

See also

• Anisocytosis

References

UpToDate Contents

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• 1. 末梢血塗抹標本の評価 evaluation of the peripheral blood smear
• 2. 遺伝性楕円赤血球症：臨床的特徴、診断、および治療 hereditary elliptocytosis clinical features diagnosis and treatment
• 3. 貧血を有する成人患者に対するアプローチ approach to the adult patient with anemia
• 4. 成人の鉄欠乏症および鉄欠乏性貧血の原因と診断 causes and diagnosis of iron deficiency and iron deficiency anemia in adults
• 5. 原発性骨髄線維症の臨床症状および診断 clinical manifestations and diagnosis of primary myelofibrosis

English Journal

• Coinheritance of Hereditary Elliptocytosis and Deletional Hemoglobin H Disease.

• Charoenkwan P1, Natesirinilkul R, Choeyprasert W, Kulsumritpon N, Sangiamporn O.
• Journal of pediatric hematology/oncology.J Pediatr Hematol Oncol.2017 Mar;39(2):e69-e70. doi: 10.1097/MPH.0000000000000750.
• PMID 28060122

• Idiopathic myelofibrosis accompanied by peritoneal extramedullary hematopoiesis presenting as refractory ascites in a dog.

• Rautenbach Y1, Goddard A1, Clift SJ2.
• Veterinary clinical pathology.Vet Clin Pathol.2017 Mar;46(1):46-53. doi: 10.1111/vcp.12430. Epub 2016 Nov 22.
• PMID 27874969

• A 2-month-old boy with hemolytic anemia and reticulocytopenia following intravenous immunoglobulin therapy for Kawasaki disease: a case report and literature review.

• Kim NY1, Kim JH1, Park JS1, Kim SH2, Cho YK2, Cha DH2, Kim KE3, Kang MS4, Lim KA3, Sheen YH3.
• Korean journal of pediatrics.Korean J Pediatr.2016 Nov;59(Suppl 1):S60-S63. doi: 10.3345/kjp.2016.59.11.S60. Epub 2016 Nov 30.
• PMID 28018448

Japanese Journal

• Multiple Diffuse Fibrosarcoma of Bone Associated with Extramedullary Hematopoiesis

• Internal medicine 37(5), 480-483, 1998-05
• NAID 10007010039

• カドミウム誘発貧血症ラットにおける脾腫の病理学的研究

• 産業医科大学雑誌 20(1), 11-19, 1998-03-01
• NAID 110001261427

• 奇形赤血球を呈した子ウシにおけるヘモグロビンタイプ, 赤血球膜蛋白構成および血漿鉄濃度

• The journal of veterinary medical science 58(7), 629-634, 1996-07-25
• NAID 110003916571

Related Pictures

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★リンクテーブル★

リンク元	「poikil」「変形赤血球症」

「poikil」

　　[★]

Greek poikilos variegated

• comb form.

• さまざまな、変化のある

• ex.

• poikiltic (adj.)
• poikilocytosis 変形赤血球症
• poikilothermia 変温性
• poikiloderma ポイキロデルマ 多形皮膚萎縮症

「変形赤血球症」

　　[★]

poikil

英

poikilocytosis

同

変形赤血球増加症、奇形赤血球症

-奇形赤血球症