変形赤血球症
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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2016/07/17 04:56:53」(JST)
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Poikilocytosis |
Acanthocytosis is one form of poikilocytosis
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Classification and external resources |
ICD-10 |
R71 |
ICD-9-CM |
790.09 |
DiseasesDB |
10207 |
[edit on Wikidata]
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Poikilocytosis refers to the presence of poikilocytes in the blood. Poikilocytes are abnormally shaped red blood cells[1] as seen on a blood film in humans and many wild and domestic species of animals, though they are common in some clinically normal small ruminants, particularly goats.
Normal red blood cells are round, flattened disks that are thinner in the middle than at the edges. A poikilocyte is an abnormally shaped cell.[2] Generally, poikilocytosis can refer to an increase in abnormal red blood cells of any shape where they make up 10% or more of the total population.
Contents
- 1 Types
- 1.1 Membrane abnormalities
- 1.2 Trauma
- 2 Treatment
- 3 Etymology
- 4 See also
- 5 References
Types
Human red blood cells showing poikilocytosis
Membrane abnormalities
- Acanthocytes or Spur/Spike cells
- Codocytes or Target cells
- Echinocytes and Burr cells
- Elliptocytes and Ovalocytes
- Spherocytes
- Stomatocytes or Mouth cells
- Drepanocytes or Sickle Cells
- Degmacytes or "bite cells"
Trauma
- Dacrocytes or Teardrop Cells
- Keratocytes
- Microspherocytes and Pyropoikilocytes
- Schistocytes
- Semilunar bodies
Treatment
In all cases, the treatment of poikilocytosis depends on its cause. For example, poikilocytosis can be caused by a vitamin deficiency (e.g. vitamin B12 or folic acid), in which case the treatment is to replenish the deficient vitamin. It can be caused by a digestive disease, such as celiac disease, in which case the solution may lie in treating the underlying celiac disease so that nutrients can be properly absorbed.
Etymology
The term derives from poikilos (ποικίλος), which means "varied" in Ancient Greek.[3][4]
See also
References
- ^ "poikilocyte" at Dorland's Medical Dictionary
- ^ Barbara J. Bain (2006). Blood cells: a practical guide. Wiley-Blackwell. pp. 71–. ISBN 978-1-4051-4265-6. Retrieved 10 November 2010.
- ^ (Greek) Triantafyllidis Online Lexicon, ποικιλόθερμος, Retrieved on 2007-01-12
- ^ "poikilo-". Wiktionary. Retrieved 14 October 2011.
Abnormal clinical and laboratory findings for blood tests (R70–R79, 790)
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Red blood cells |
Size |
- Anisocytosis
- Macrocyte
- Microcyte
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Shape |
- Poikilocytosis
- membrane abnormalities:
- Acanthocyte
- Codocyte
- Ovalocyte
- Spherocyte
- Dacrocyte
- Echinocyte
- Schistocyte
- Degmacyte
- Drepanocyte
- Stomatocyte
- Knizocyte
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Hemoglobinization |
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Inclusion bodies |
- Developmental
- Howell–Jolly body
- Basophilic stippling
- Pappenheimer bodies
- Cabot rings
- Hemoglobin precipitation
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Other |
- Rouleaux
- Reticulocyte
- Elevated ESR
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Lymphocytes |
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Small molecules |
Blood sugar |
- Hypoglycemia
- Hyperglycemia
- Prediabetes
- Impaired fasting glucose
- Impaired glucose tolerance
- Oxyhyperglycemia
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Nitrogenous |
- Azotemia
- Hyperuricemia
- Hypouricemia
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Proteins |
LFT |
- Elevated transaminases
- Elevated ALP
- Hypoproteinemia
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Other |
- Elevated cardiac markers
- Elevated alpha-fetoprotein
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Minerals |
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Pathogens/sepsis |
- Bacteremia
- Viremia
- Fungemia
- Parasitemia
- Algaemia
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UpToDate Contents
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English Journal
- Coinheritance of Hereditary Elliptocytosis and Deletional Hemoglobin H Disease.
- Charoenkwan P1, Natesirinilkul R, Choeyprasert W, Kulsumritpon N, Sangiamporn O.
- Journal of pediatric hematology/oncology.J Pediatr Hematol Oncol.2017 Mar;39(2):e69-e70. doi: 10.1097/MPH.0000000000000750.
- PMID 28060122
- Idiopathic myelofibrosis accompanied by peritoneal extramedullary hematopoiesis presenting as refractory ascites in a dog.
- Rautenbach Y1, Goddard A1, Clift SJ2.
- Veterinary clinical pathology.Vet Clin Pathol.2017 Mar;46(1):46-53. doi: 10.1111/vcp.12430. Epub 2016 Nov 22.
- PMID 27874969
- A 2-month-old boy with hemolytic anemia and reticulocytopenia following intravenous immunoglobulin therapy for Kawasaki disease: a case report and literature review.
- Kim NY1, Kim JH1, Park JS1, Kim SH2, Cho YK2, Cha DH2, Kim KE3, Kang MS4, Lim KA3, Sheen YH3.
- Korean journal of pediatrics.Korean J Pediatr.2016 Nov;59(Suppl 1):S60-S63. doi: 10.3345/kjp.2016.59.11.S60. Epub 2016 Nov 30.
- PMID 28018448
Japanese Journal
- Multiple Diffuse Fibrosarcoma of Bone Associated with Extramedullary Hematopoiesis
- カドミウム誘発貧血症ラットにおける脾腫の病理学的研究
- 奇形赤血球を呈した子ウシにおけるヘモグロビンタイプ, 赤血球膜蛋白構成および血漿鉄濃度
- The journal of veterinary medical science 58(7), 629-634, 1996-07-25
- NAID 110003916571
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★リンクテーブル★
[★]
- Greek poikilos variegated
[★]
- poikil
- 英
- poikilocytosis
- 同
- 変形赤血球増加症、奇形赤血球症
-奇形赤血球症