- 関
- platelet activation
WordNet
- tiny bits of protoplasm found in vertebrate blood; essential for blood clotting (同)blood_platelet, thrombocyte
- causing motion or action or change (同)actuating
UpToDate Contents
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English Journal
- Expression of the platelet-activating factor receptor enhances benzyl isothiocyanate-induced apoptosis in murine and human melanoma cells.
- Sahu RP1.
- Molecular medicine reports.Mol Med Rep.2015 Jul;12(1):394-400. doi: 10.3892/mmr.2015.3371. Epub 2015 Feb 18.
- Melanoma cells often express platelet‑activating factor receptor (PAF‑R), which has been demonstrated to increase metastatic behavior. However, the effect of PAF‑R on the responsiveness of melanoma to naturally occurring cytotoxic agents remains to be elucidated. The present study aimed to det
- PMID 25695262
- Molecular docking study on platelet-activating factor antagonistic activity of bioactive compounds isolated from Guttiferae and Ardisia species.
- Jasamai M1, Jalil J, Jantan I.
- Natural product research.Nat Prod Res.2015 Jun;29(11):1055-8. doi: 10.1080/14786419.2014.971317. Epub 2014 Oct 21.
- A handful of bioactive compounds from plants have been reported to possess platelet-activating factor (PAF) antagonist activity. However, their mode of action is not well understood. Selected bioactive compounds that exhibit PAF antagonist activity and synthetic PAF antagonists were subjected to doc
- PMID 25332053
- SIRT1 attenuates PAF-induced MMP-2 production via down-regulation of PAF receptor expression in vascular smooth muscle cells.
- Kim YH1, Bae JU1, Lee SJ1, Park SY1, Kim CD2.
- Vascular pharmacology.Vascul Pharmacol.2015 May 9. pii: S1537-1891(15)00103-2. doi: 10.1016/j.vph.2015.04.015. [Epub ahead of print]
- Silent mating type information regulation 2 homolog 1 (SIRT1) is known as a key regulator in the protection of various vascular disorders, however, no direct evidences have been reported in the progression of atherosclerosis. Considering the pivotal role of matrix metalloproteinase-2 (MMP-2) in plaq
- PMID 25967595
Japanese Journal
- Heparin投与に依存しない自然発生型ヘパリン起因性血小板減少症
- 免疫学的特異性に基づいたヘパリン起因性血小板減少症(HIT)の適切な診断と治療
Related Links
- QUESTION: Name three factors that not only are produced or released as a result of platelet activation but also cause platelet activation. ANSWER QUESTION: Is this an example of negative or positive feedback? ANSWER
- Original Article from The New England Journal of Medicine — Platelet-Activating Factor, PAF Acetylhydrolase, and Severe Anaphylaxis ... Results Mean (±SD) serum PAF levels were significantly higher in patients with ...
Related Pictures
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血小板活性化因子、PAF