plasmacytoid dendritic cell

形質細胞様樹状細胞

関

dendritic cell、interdigitating cell、interdigitating dendritic cell、PDC、veiled cell

WordNet

1. small room in which a monk or nun lives (同)cubicle
2. a device that delivers an electric current as the result of a chemical reaction (同)electric cell
3. a room where a prisoner is kept (同)jail cell, prison cell
4. (biology) the basic structural and functional unit of all organisms; they may exist as independent units of life (as in monads) or may form colonies or tissues as in higher plants and animals
5. any small compartment; "the cells of a honeycomb"
6. a small unit serving as part of or as the nucleus of a larger political movement (同)cadre
7. (neuroscience) of or relating to or resembling a dendrite; "dendritic fiber"

PrepTutorEJDIC

1. (刑務所の)『独房』;(修道院の)小さい独居室 / (ミツバチの)みつ房,巣穴 / 小さい部屋 / 『細胞』 / 電池 / 花粉室 / (共産党などの)細胞

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/08/13 19:08:22」(JST)

wiki en

[Wiki en表示]

Plasmacytoid dendritic cells (pDCs) are innate immune cells that circulate in the blood and are found in peripheral lymphoid organs. They constitute < 0.4% of peripheral blood mononuclear cells (PBMC). In humans these cells express the surface markers CD123, BDCA-2(CD303) and BDCA-4(CD304), but do not express high levels of CD11c or CD14, which distinguishes them from conventional dendritic cells or monocytes, respectively. Mouse pDC express CD11c, B220, BST-2/Tetherin (mPDCA) and Siglec-H and are negative for CD11b. As components of the innate immune system, these cells express intracellular Toll-like receptors 7 and 9 which detect ssRNA and CpG DNA motifs, respectively. Upon stimulation and subsequent activation, these cells produce large amounts of type I interferon (mainly IFN-α (alpha) and IFN-β (beta)), which are critical pleiotropic anti-viral compounds mediating a wide range of effects.

The number of circulating pDCs are found to be decreased during chronic HIV infection as well as HCV infection.

References

UpToDate Contents

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• 1. 炎症性ミオパチーの病因pathogenesis of inflammatory myopathies [show details]
  …abundant . Although the nature of these CD4+ cells is not fully understood, many of these are plasmacytoid dendritic cells (pDCs) , immune cells that are proficient at producing type 1 interferons (IFN-alpha and…
• 2. 芽球性形質細胞様樹状細胞腫瘍blastic plasmacytoid dendritic cell neoplasm [show details]
  …and confirmation that BPDCN is derived from plasmacytoid dendritic cells (type 2 dendritic cells), the current nomenclature, blastic plasmacytoid dendritic cell neoplasm, was chosen to describe the entity …
• 3. 皮下蜂窩織炎様T細胞性リンパ腫の臨床症状、病理学的特徴、および診断clinical manifestations pathologic features and diagnosis of subcutaneous panniculitis like t cell lymphoma [show details]
  …granzyme B, and/or perforin). Blastic plasmacytoid dendritic cell neoplasm (BPDCN; previously called type 2 dendritic cell acute leukemia, acute plasmacytoid dendritic cell leukemia, or CD4+CD56+ hematodermic …
• 4. 尋常性乾癬の病態生理pathophysiology of plaque psoriasis [show details]
  …dendritic cells (plasmacytoid dendritic cells and various myeloid dendritic cells) have been implicated as contributors to psoriasis. Plasmacytoid dendritic cells – Plasmacytoid dendritic cells are a unique …
• 5. ナチュラルキラー（NK）細胞大顆粒リンパ球性白血病natural killer nk cell large granular lymphocyte leukemia [show details]
  …infection with EBV. Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare, aggressive neoplasm arising from precursors of the type 2 or plasmacytoid dendritic cells. Most patients present with …

English Journal

• HBs antigen and mannose loading on the surface of iron oxide nanoparticles in order to immuno-targeting: fabrication, characterization, cellular and humoral immunoassay.

• Rezaei M, Hosseini SN, Khavari-Nejad RA, Najafi F, Mahdavi M.
• Artificial cells, nanomedicine, and biotechnology. 2019 Dec;47(1)1543-1558.
• Mannosylation of nanovaccine is an appropriate strategy for targeting the mannose receptors on DCs. Here, HBsAg and mannose loaded on the surface of iron oxide nanoparticles to increases HBsAg vaccine potency. Nanoparticles are made by co-precipitation method and bonded to the HBsAg and mannose by c
• PMID 31007088

• IL-33 drives the antitumour effects of dendritic cells via upregulating CYLD expression in pulmonary adenocarcinoma.

• Zhang J, Chen Y, Chen K, Huang Y, Xu X, Chen Q, Huang C, Luo J, Lin X.
• Artificial cells, nanomedicine, and biotechnology. 2019 Dec;47(1)1335-1341.
• Lung adenocarcinoma is one of the leading causes of cancer-related death worldwide. Low expression of Interleukin-33 (IL-33) was reported to be associated with the progression of pulmonary adenocarcinoma. However, the IL-33-mediated immunoregulation in pulmonary adenocarcinoma remains unclear. In th
• PMID 30964341

• Folate-modified and curcumin-loaded dendritic magnetite nanocarriers for the targeted thermo-chemotherapy of cancer cells.

• Montazerabadi A, Beik J, Irajirad R, Attaran N, Khaledi S, Ghaznavi H, Shakeri-Zadeh A.
• Artificial cells, nanomedicine, and biotechnology. 2019 Dec;47(1)330-340.
• A novel multifunctional nanoplatform constructed from methoxy-PEGylated poly(amidoamine) (PAMAM) generation 3 dendrimers with superparamagnetic iron oxide nanoparticles (SPIONs) entrapped in their core, containing curcumin as the payload drug and folic acid (folate) as the targeting ligand (abbrevia
• PMID 30688084

Japanese Journal

• 症例 眼瞼腫瘤を形成したBlastic Plasmacytoid Dendritic Cell Neoplasmの1例

• 皮膚科の臨床 57(4), 445-449, 2015-04
• NAID 40020439805

• 症例 Blastic Plasmacytoid Dendritic Cell Neoplasmの1例

• 皮膚科の臨床 57(3), 337-340,247-248, 2015-03
• NAID 40020382697

• 末梢血および骨髄に白血病芽球様細胞を認め，診断に苦慮した芽球形質細胞様樹状細胞腫瘍の1例

• 医学検査 64(5), 553-557, 2015
• NAID 130005109636

Related Links

• Blastic plasmacytoid dendritic cell neoplasm

Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare, clinically aggressive hematologic malignancy that most commonly manifests as cutaneous lesions with or without bone marrow involvement and leukemic dissemination ...

• Plasmacytoid dendritic cells in immunity - Nature Immunology

Human and mouse plasmacytoid dendritic cells have been shown to correspond to a specialized cell population that produces large amounts of type I interferons in response to viruses, the so-called natural interferon ...

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★リンクテーブル★

リンク元	「形質細胞様樹状細胞」「veiled cell」「PDC」「interdigitating cell」
拡張検索	「plasmacytoid dendritic cells」
関連記事	「dendritic」「cell」

「形質細胞様樹状細胞」

　　[★]

英

plasmacytoid dendritic cell、PDC

関

樹状細胞、ピルビン酸デヒドロゲナーゼ複合体、指状嵌入細胞、ベール細胞、指状突起樹状細胞

「veiled cell」

　　[★]

ベール細胞、ヴェール細胞

関

dendritic cell、interdigitating cell、interdigitating dendritic cell、plasmacytoid dendritic cell

「PDC」

　　[★]

• 形質細胞様樹状細胞、ピルビン酸デヒドロゲナーゼ複合体

関

plasmacytoid dendritic cell、pyruvate dehydrogenase complex

「interdigitating cell」

　　[★]

指状嵌入細胞、指状突起細胞

関

dendritic cell、interdigitating dendritic cell、plasmacytoid dendritic cell、veiled cell

「plasmacytoid dendritic cells」

　　[★]

関

dendritic cells

関

dendritic cells

「dendritic」

　　[★]

• 樹状の、樹枝状の、樹状突起の

関

arboreal、arboroid、dendrite

　

「cell」

　　[★] 細胞