同: PLEVA

WordNet

any of several skin disorders characterized by shedding dry flakes of skin
the base of the natural system of logarithms; approximately equal to 2.718282...

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/10/12 17:14:09」(JST)

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Pityriasis lichenoides et varioliformis acuta (also known as "acute guttate parapsoriasis", "acute parapsoriasis", "acute pityriasis lichenoides", "Mucha–Habermann disease", "parapsoriasis acuta", "parapsoriasis lichenoides et varioliformis acuta", and "parapsoriasis varioliformis"^[1]^:456^[2]^:736) is a disease of the immune system. It is the more severe version of pityriasis lichenoides chronica. The disease is characterized by rashes and small lesions on the skin. The disease is more common in males and usually occurs in young adulthood, although it has been seen in every age group and every race. It is possible for the disease to go into remission for short periods of time or forever.

Diagnosis

It is commonly misdiagnosed as chickenpox or rosacea. Pleva is also often misidentified as a form of staph. The most accurate way to diagnose it is by biopsy. This disease has not been known to be life-threatening. However, there may be mutations of the disease that can cause ulcers on the exterior.

Causes

There is no known cause of this disease;^[3] There is some evidence associating it with Parvovirus B19.^[4]

Treatment

It is not contagious and currently there is no cure for the disease, although the lesions can be treated with ultraviolet therapy as well as topical steroids and antibiotics.^[5]

Treatment often involves multiple therapies that address the immune system and bacterial, viral, or dermatological causes.

Eponym

It is named for Rudolf Habermann (1884–1941), a German dermatologist, and Viktor Mucha, an Austrian dermatologist.

References

^ Freedberg, et al. (2003). Fitzpatrick's Dermatology in General Medicine. (6th ed.). McGraw-Hill. ISBN 0-07-138076-0.
^ James, William D.; Berger, Timothy G. (2006). Andrews' Diseases of the Skin: clinical Dermatology. Saunders Elsevier. ISBN 0-7216-2921-0.
^ "PLEVA, or Mucha-Habermann disease - MayoClinic.com". Archived from the original on 2007-07-15. Retrieved 2007-11-18.
^ Tomasini D, Tomasini CF, Cerri A, et al. (2004). "Pityriasis lichenoides: a cytotoxic T-cell-mediated skin disorder. Evidence of human parvovirus B19 DNA in nine cases". J. Cutan. Pathol. 31 (8): 531–8. doi:10.1111/j.0303-6987.2004.00186.x. PMID 15268707.
^ Linsey Davis (January 4, 2013). "High School Basketball Star Must Tan to Treat Rare Disease". ABC News. Retrieved January 4, 2013. Doctors say the ultraviolet technique is so effective that Borrelli cannot miss a single day of tanning, especially since the disease can resurface at any time and cause life-threatening complications in adults.

External links

DermNet scaly/pityriasis-lichenoides

UpToDate Contents

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1. 急性痘瘡状苔癬状粃糠疹（PLEVA） pityriasis lichenoides et varioliformis acuta pleva
2. 慢性苔癬状粃糠疹 pityriasis lichenoides chronica
3. リンパ腫様丘疹症 lymphomatoid papulosis
4. 昆虫咬傷 insect bites
5. UVA1療法 uva1 phototherapy

English Journal

Pityriasis lichenoides et varioliformis acuta exacerbated after tonsillectomy.

Noda S, Asano Y, Sato S.
European journal of dermatology : EJD.Eur J Dermatol.2011 Jul 1. [Epub ahead of print]
PMID 21719399

Pityriasis lichenoides et varioliformis acuta and pityriasis lichenoides chronica: comparison of lesional T-cell subsets and investigation of viral associations.

Kim JE, Yun WJ, Mun SK, Yoon GS, Huh J, Choi JH, Chang S.SourceDepartment of Dermatology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea Department of Otorhinolaryngology-Head and Neck Surgery, Chung-Ang University College of Medicine, Seoul, Korea Department of Pathology, School of Medicine, Kyungpook National University, Daegu, Korea Department of Pathology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Journal of cutaneous pathology.J Cutan Pathol.2011 Apr 26. doi: 10.1111/j.1600-0560.2011.01717.x. [Epub ahead of print]
Background: Pityriasis lichenoides (PL) exhibits a broad clinical spectrum that includes both acute and chronic forms. The precise biologic mechanisms underlying PL remain unclear. Objectives: To evaluate the immunohistochemical characteristics of PL and to investigate lesional T-cell subsets and th
PMID 21518386