English Journal

Progressive facilitation of antegrade conduction via an accessory pathway in a patient with Wolff-Parkinson-White syndrome and permanent atrial fibrillation.

Takahashi N, Ooie T, Nakagawa M, Hara M, Saikawa T, Yoshimatsu H.SourceDepartment of Internal Medicine 1, Oita University, Japan.
Internal medicine (Tokyo, Japan).Intern Med.2005 Dec;44(12):1264-8.
The case of a 64-year-old man with Wolff-Parkinson-White syndrome and permanent atrial fibrillation (AF) is reported. The patient was admitted due to electrocardiographic feature of AF with rapid conduction over the left-sided accessory pathway. Administration of pirmenol effectively suppressed the
PMID 16415547

Appropriate dosing of antiarrhythmic drugs in Japan requires therapeutic drug monitoring.

Takada M, Goto T, Kotake T, Saito M, Kawato N, Nakai M, Gunji T, Shibakawa M.SourceDepartment of Pharmacy, National Cardiovascular Center, Suita-city, Osaka, Japan. takada@hsp.ncvc.go.jp
Journal of clinical pharmacy and therapeutics.J Clin Pharm Ther.2005 Feb;30(1):5-12.
OBJECTIVE: In general, drugs are used in accordance with an approved dosage regimen in expectation of an appropriate balance between efficacy and toxicity. However, dose control of drugs with a narrow therapeutic range and marked intersubject variability in pharmacokinetics should be established thr
PMID 15658999

A patient responding to combined therapy with pirmenol and midodrine for refractory neurally mediated syncope complicated by prostatic hypertrophy.

Mizuguchi Y, Ishimoto T, Kageyama N, Oishi Y, Emi S, Nagase N, Oki T.SourceCardiovascular Section, Higashi Tokushima National Hospital, National Hospital Organization, 1-1 Ohmukai-Kita, Ohtera, Itano, Tokushima 779-0193, Japan. mizuguchi@higasitokusima.hosp.go.jp
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy.Cardiovasc Drugs Ther.2004 Sep;18(5):405-8.
A 67-year-old man with neurally mediated syncope (NMS) complicated by prostatic hypertrophy responded well to combined therapy with pirmenol and midodrine. In 2003, syncope occurred while the patient was driving a car. Results of head-up tilt-table testing (HUT) suggested a mixed type of NMS. Oral a
PMID 15717144

Japanese Journal

Progressive Facilitation of Antegrade Conduction via an Accessory Pathway in a Patient with Wolff-Parkinson-White Syndrome and Permanent Atrial Fibrillation

Takahashi Naohiko,Ooie Tatsuhiko,Nakagawa Mikiko [他],HARA Masahide,SAIKAWA Tetsunori,YOSHIMATSU Hironobu
Internal medicine 44(12), 1264-1268, 2005-12-01
… Administration of pirmenol effectively suppressed the ventricular response via an accessory pathway. …
NAID 10016917510