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WordNet
- street name for lysergic acid diethylamide (同)back breaker, battery-acid, dose, dot, Elvis, loony toons, Lucy in the sky with diamonds, pane, superman, window pane, Zen
- any of various water-soluble compounds having a sour taste and capable of turning litmus red and reacting with a base to form a salt
- having the characteristics of an acid; "an acid reaction"
PrepTutorEJDIC
- 酸性の / 酸味のある,すっぱい(sour) / (言葉・態度などが)厳しい,しんらつな / 酸 / すっぱいもの / 《俗》=LSD
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2013/12/25 22:21:16」(JST)
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Pipemidic acid
|
Systematic (IUPAC) name |
8-Ethyl-5-oxo-2-piperazin-1-yl-5,8-dihydropyrido[2,3-d]pyrimidine-6-carboxylic acid |
Clinical data |
AHFS/Drugs.com |
International Drug Names |
Pregnancy cat. |
? |
Legal status |
? |
Identifiers |
CAS number |
51940-44-4 |
ATC code |
J01MB04 |
PubChem |
CID 4831 |
UNII |
LT12J5HVR8 Y |
KEGG |
D08379 |
ChEMBL |
CHEMBL30116 |
Chemical data |
Formula |
C14H17N5O3 |
Mol. mass |
303.32 g/mol |
Pipemidic acid is a member of the pyridopyrimidine class of antibacterials, which display some overlap in mechanism of action with analogous pyridone-containing quinolones.
Antibacterials: nucleic acid inhibitors (J01E, J01M)
|
|
Antifolates
(inhibits
purine metabolism,
thereby inhibiting
DNA and RNA synthesis) |
DHFR inhibitor |
- 2,4-Diaminopyrimidine
- Trimethoprim#
- Brodimoprim
- Tetroxoprim
- Iclaprim†
|
|
Sulfonamides
(DHPS inhibitor) |
Short-
acting |
- Sulfaisodimidine
- Sulfamethizole
- Sulfadimidine
- Sulfapyridine
- Sulfafurazole
- Sulfanilamide
- Sulfathiazole
- Sulfathiourea
|
|
Intermediate-
acting |
- Sulfamethoxazole
- Sulfadiazine#
- Sulfamoxole
|
|
Long-
acting |
- Sulfadimethoxine
- Sulfadoxine
- Sulfalene
- Sulfametomidine
- Sulfametoxydiazine
- Sulfamethoxypyridazine
- Sulfaperin
- Sulfamerazine
- Sulfaphenazole
- Sulfamazone
|
|
Other/ungrouped |
- Sulfacetamide
- Sulfadicramide
- Sulfametrole
|
|
|
Combinations |
- Trimethoprim/sulfamethoxazole#
|
|
|
Topoisomerase
inhibitors/
quinolones/
(inhibits
DNA replication) |
1st g. |
- Cinoxacin‡
- Flumequine
- Nalidixic acid
- Oxolinic acid
- Pipemidic acid
- Piromidic acid
- Rosoxacin
|
|
Fluoro-
quinolones |
2nd g. |
- Ciprofloxacin#
- Enoxacin‡
- Fleroxacin‡
- Lomefloxacin
- Nadifloxacin
- Ofloxacin
- Norfloxacin
- Pefloxacin
- Rufloxacin
|
|
3rd g. |
- Balofloxacin
- Grepafloxacin‡
- Levofloxacin
- Pazufloxacin
- Sparfloxacin‡
- Temafloxacin‡
- Tosufloxacin
|
|
4th g. |
- Besifloxacin
- Clinafloxacin†
- Garenoxacin
- Gemifloxacin
- Moxifloxacin
- Gatifloxacin‡
- Sitafloxacin
- Trovafloxacin‡/Alatrofloxacin‡
- Prulifloxacin
|
|
Vet. |
- Danofloxacin
- Difloxacin
- Enrofloxacin
- Ibafloxacin
- Marbofloxacin
- Orbifloxacin
- Pradofloxacin
- Sarafloxacin
|
|
Related (DG) |
- Aminocoumarins: Novobiocin
|
|
|
|
Anaerobic DNA
inhibitors |
Nitro- imidazole derivatives |
- Metronidazole#
- Tinidazole
- Ornidazole
|
|
Nitrofuran derivatives |
- Nitrofurantoin#
- Furazolidone‡
- Nifurtoinol
|
|
|
RNA synthesis |
Rifamycins/
RNA polymerase |
- Rifampicin#
- Rifabutin
- Rifapentine
- Rifaximin
|
|
|
- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III
|
|
gr+f/gr+a (t)/gr-p (c)/gr-o
|
drug (J1p, w, n, m, vacc)
|
|
|
|
English Journal
- A rapid and sensitive resonance Rayleigh scattering spectra method for the determination of quinolones in human urine and pharmaceutical preparation.
- Qiao M1, Wang Y, Liu S, Liu Z, Yang J, Zhu J, Hu X.
- Luminescence : the journal of biological and chemical luminescence.Luminescence.2015 Mar;30(2):207-15. doi: 10.1002/bio.2714. Epub 2014 Jun 27.
- A new method based on resonance Rayleigh scattering (RRS) was proposed for the determination of quinolones (QNS) at the nanogram level. In pH 3.3-4.4 Britton-Robinson buffer medium, quinolones such as ciprofloxacin, pipemidic acid (PIP), lomefloxacin (LOM), norfloxacin (NOR) and sarafloxacin (SAR)
- PMID 24976410
- Clinical evaluation of herbal coded formulation Cran-off to Urixin in the treatment of urinary tract infection.
- Shaheen G1, Usmanghani K2, Nazar H2, Akhtar N1.
- Pakistan journal of pharmaceutical sciences.Pak J Pharm Sci.2015 Mar;28(2):557-9.
- Urinary Tract Infections are the largest group of infections after the respiratory tract infections. In 85% of the cases the causative organism is E. Coli. A clinical trial was conducted to evaluate the efficacy of coded herbal formulation "Cranoff" (Test drug) for the treatment of Urinary tract inf
- PMID 25730788
- Multiresidue determination of fluoroquinolones in poultry muscle and kidney according to the regulation 2002/657/EC. A systematic comparison of two different approaches: Liquid chromatography coupled to high-resolution mass spectrometry or tandem mass spectrometry.
- Rocha DG1, Santos FA2, da Silva JC1, Augusti R1, Faria AF3.
- Journal of chromatography. A.J Chromatogr A.2015 Jan 30;1379:83-91. doi: 10.1016/j.chroma.2014.12.058. Epub 2014 Dec 29.
- This work involved the optimization and validation of two methods according to the Commission Decision 2002/657/EC directives for determining fluoroquinolones residues in samples of poultry muscle and kidney: ciprofloxacin, danofloxacin, difloxacin, enrofloxacin, flumequine, marbofloxacin, nalidixic
- PMID 25577647
Japanese Journal
- Diclofenac in the Management of E. coli Urinary Tract Infections
- Mazumdar Kaushiki,Dutta Noton Kumar,Dastidar Sujata G.,本橋 登,白瀧 義明
- In Vivo : International Journal of Experimental and Clinical Pathophysiology of Drug Research 20(5), 613-619, 2006-09
- … The isolates were decreasinglyresistant to ampicillin, tobramycin, augmentin, nalidixic acid,cefuroxime, nitrofurantoin, kanamycin, pipemidic acid,chloramphenicol, cefotaxime, cefamendol, ofloxacin,ceftizoxime, norfloxacin and amikacin. …
- NAID 120005518458
- Synthesis, Characterization, and Antibacterial Activities of Some Rare Earth Metal Complexes of Pipemidic Acid
- , , [他], ,
- Chemical & pharmaceutical bulletin 51(5), 494-498, 2003-05-01
- … Eight new solid complexes of pipemidic acid (PPA) with trichlorizated rare earth metals LaCl_3, CeCl_3, PrCl_3, NdCl_3, SmCl_3, TbCl_3, DyCl_3, and YCl_3 have been synthesized. …
- NAID 110003615338
- The Influence of Chitosan on in Vitro Properties of Eudragit RS Microspheres
- , , [他],
- Chemical & pharmaceutical bulletin 51(4), 359-364, 2003-04-01
- … Pipemidic acid content increased with increasing fraction particle size, but not with increasing stirring rate as it was observed for microspheres without chitosan. … We presume that high pipemidic acid content in larger microspheres is a consequence of cumulation of undissolved pipeinidic acid particles in larger droplets during microspheres preparation procedure. …
- NAID 110003615306
Related Links
- Pipemidic Acid [PPA] ピペミド酸, 合成抗菌剤(オールドキノロン系) 1. 商品名 先発品 ドルコール錠250mg 【大日本住友製薬】 後発品 後発品2件 を表示 カルノマチン錠250mg 【イセイ】 ペピミドール錠250mg 【陽進堂】 2. 日本における ...
- pipemidic acid a quinolone antibiotic, similar to nalidixic acid. ... Disclaimer All content on this website, including dictionary, thesaurus, literature, geography, and other reference data is for informational purposes only.
Related Pictures
★リンクテーブル★
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- 英
- pipemidic acid
- 化
- ピペミド酸三水和物 pipemidic acid trihydrate
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