WordNet
- the 1st letter of the Roman alphabet (同)a
- the blood group whose red cells carry the A antigen (同)type_A, group A
- a cellular structure that is postulated to exist in order to mediate between a chemical agent that acts on nervous tissue and the physiological response
PrepTutorEJDIC
- answer / ampere
- =sense organ / 受信装置
UpToDate Contents
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- 1. 膜性腎症の原因および診断 causes and diagnosis of membranous nephropathy
- 2. 特発性膜性腎症の治療 treatment of idiopathic membranous nephropathy
- 3. 糸球体の免疫障害の機序 mechanisms of immune injury of the glomerulus
- 4. 膜性腎症と腎移植 membranous nephropathy and renal transplantation
- 5. 膜性ループス腎炎の臨床的特徴および治療 clinical features and therapy of membranous lupus nephritis
English Journal
- Aberrant methylation of the M-type phospholipase A2 receptor gene in leukemic cells.
- Menschikowski M, Platzbecker U, Hagelgans A, Vogel M, Thiede C, Schönefeldt C, Lehnert R, Eisenhofer G, Siegert G.AbstractABSTRACT: BACKGROUND: The M-type phospholipase A2 receptor (PLA2R1) plays a crucial role in several signaling pathways and may act as tumor-suppressor. This study examined the expression and methylation of the PLA2R1 gene in Jurkat and U937 leukemic cell lines and its methylation in patients with myelodysplastic syndrome (MDS) or acute leukemia.
- BMC cancer.BMC Cancer.2012 Dec 5;12(1):576. [Epub ahead of print]
- ABSTRACT: BACKGROUND: The M-type phospholipase A2 receptor (PLA2R1) plays a crucial role in several signaling pathways and may act as tumor-suppressor. This study examined the expression and methylation of the PLA2R1 gene in Jurkat and U937 leukemic cell lines and its methylation in patients with my
- PMID 23217014
- Recurrent Membranous Nephropathy in an Allograft Caused by IgG3κ Targeting the PLA2 Receptor.
- Debiec H, Hanoy M, Francois A, Guerrot D, Ferlicot S, Johanet C, Aucouturier P, Godin M, Ronco P.SourceINSERM Unit 702, Hôpital Tenon, 4 rue de la Chine, 75020 Paris, France. pierreronco@yahoo.fr.
- Journal of the American Society of Nephrology : JASN.J Am Soc Nephrol.2012 Dec;23(12):1949-54. doi: 10.1681/ASN.2012060577. Epub 2012 Nov 2.
- Up to 80% of patients with idiopathic membranous nephropathy have non-complement-fixing IgG4 autoantibodies to the phospholipase A2 receptor (PLA2R). Membranous nephropathy recurs in approximately 40% of patients after kidney transplantation, but the mechanism is unknown. Here, we describe a patient
- PMID 23123401
Japanese Journal
- A [Lys^<49>]phospholipase A_2 from Protobothrops flavoviridis Venom Induces Caspase-Independent Apoptotic Cell Death Accompanied by Rapid Plasma-Membrane Rupture in Human Leukemia Cells
- MURAKAMI Tatsuo,KAMIKADO Nobuyuki,FUJIMOTO Ryo,HAMAGUCHI Kazuhiko,NAKAMURA Hitomi,CHIJIWA Takahito,OHNO Motonori,ODA UEDA Naoko
- Bioscience, biotechnology, and biochemistry 75(5), 864-870, 2011-05-23
- … venom contains plural phospholipase A<SUB>2</SUB> … its cell-surface receptor. …
- NAID 10028272404
- 海外論文紹介 : M-Type Phospholipase A2 Receptor as Target Antigen in Idiopathic Membranous Nephropathy
- Activation of Cytosolic Phospholipase A_2α by Epidermal Growth Factor (EGF) and Phorbol Ester in HeLa Cells : Different Effects of Inhibitors for EGF Receptor, Protein Kinase C, Src, and C-Raf
- MATSUZAWA Yasuo,KIUCHI Yoshiaki,TOYOMURA Kaori,MATSUMOTO Ikiru,NAKAMURA Hiroyuki,FUJINO Hiromichi,MURAYAMA Toshihiko,KAWASHIMA Tatsuo
- Journal of pharmacological sciences 111(2), 182-192, 2009-10-20
- … In several types of cancer cells, prostaglandins produced via the over-expression of epidermal growth factor receptor (EGFR) and cyclooxygenases regulate cell growth. … α-type cytosolic phospholipase A<sub>2</sub> …
- NAID 10025739155
Related Links
- Anti-Phospholipase-A2-Receptor (PLA2R) autoantibodies are a milestone in the diagnosis of membranous nephropathy (MN). Anti-PLA2R antibodies are a highly specific and highly sensitive marker for primary MN (pMN), ideally ...
- 1. J Am Soc Nephrol. 2011 Jun;22(6):1137-43. doi: 10.1681/ASN.2010090967. Epub 2011 May 12. Anti-phospholipase A2 receptor antibody in membranous nephropathy. Qin W(1), Beck LH Jr, Zeng C, Chen Z, Li S, Zuo ...
★リンクテーブル★
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- 英
- phospholipase A2 receptor
- 関
- ホスホリパーゼA2レセプター
[★]
- 英
- phospholipase A2 receptor
- 関
- ホスホリパーゼA2受容体
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