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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2019/06/30 06:26:38」(JST)

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Overexpression of human SPATA17 protein induces germ cell apoptosis in transgenic male mice.

Nie DS, Liu Y, Juan H, Yang X.SourceDepartment of Chemistry and Chemical Engineering, Hunan Institute of Science and Technology, YueYang, 414006, Hunan, China, ndz1997@126.com.
Molecular biology reports.Mol Biol Rep.2013 Feb;40(2):1905-10. doi: 10.1007/s11033-012-2246-z. Epub 2012 Oct 19.
SPATA17 is a new testis-specific-expressed gene that is involved in Spermatogenesis process. Previous studies show that SPATA17 was involved in acceleration of cell apoptosis in GC-1 cell lines. To further investigate specific roles of SPATA17 in Spermatogenesis in vivo, we generated transgenic mice
PMID 23079716

Varga A, Gráczer E, Chaloin L, Liliom K, Závodszky P, Lionne C, Vas M.SourceInstitute of Enzymology, Research Centre for Natural Sciences, Hungarian Academy of Sciences, P.O. Box 7, H-1518 Budapest, Hungary. Electronic address: matkovics.varga.andrea@ttk.mta.hu.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.Eur J Pharm Sci.2013 Jan 23;48(1-2):307-15. doi: 10.1016/j.ejps.2012.11.007. Epub 2012 Nov 28.
Nucleoside analogues, used in HIV-therapy, need to be phosphorylated by cellular enzymes in order to become potential substrates for HIV reverse transcriptase. After incorporation into the viral DNA chain, because of lacking of their 3'-hydroxyl groups, they stop the elongation process and lead to t
PMID 23201309

Chaker S, Kashat L, Voisin S, Kaur J, Kak I, Macmillan C, Ozcelik H, Siu KW, Ralhan R, Walfish PG.SourceAlex and Simona Shnaider Laboratory in Molecular Oncology, Samuel Lunenfeld Research Institute, Mount Sinai Hospital, 60 Murray Street,, Toronto, Ontario, Canada, M5T 3L9; Institute of Medical Science, University of Toronto, 2374 Medical Science Building, 1 King's College Circle, Toronto, Ontario, Canada, M5S 1A8.
Proteomics.Proteomics.2013 Jan 14. doi: 10.1002/pmic.201200356. [Epub ahead of print]
Using proteomics in tandem with bioinformatics, the secretomes of non-aggressive and aggressive thyroid carcinoma (TC) cell lines were analyzed to detect potential biomarkers for tumor aggressiveness. A panel of nine proteins, activated leukocyte cell adhesion molecule (ALCAM/ CD166), tyrosine-prote
PMID 23319340

Light/dark cycling causes delayed lipid accumulation and increased photoperiod-based biomass yield by altering metabolic flux in oleaginous Chlamydomonas sp.

Kato Yuichi,Fujihara Yusuke,Vavricka Christopher J.,Chang Jo-Shu,Hasunuma Tomohisa,Kondo Akihiko
Biotechnology for Biofuels (12), 39, 2019-02-21
… Dynamic metabolic profiling showed higher levels of lipid/carbohydrate anabolism (including production of 3-phosphoglycerate, fructose 6-phosphate, glucose 6-phosphate, phosphoenolpyruvate and acetyl-CoA) from CO2 under the LD condition, indicating higher CO2 fixation than that of the LL condition. … Conversions of phosphoenolpyruvate to pyruvate and 3-phosphoglycerate to glycerol 3-phosphate are the candidate rate-limiting steps responsible for delayed lipid accumulation. …
NAID 120006599091

Role of amino acid metabolism and autophagy in chemical-induced abnormal lipid metabolism and fatty liver

Byung-Hoon LEE
日本毒性学会学術年会 46.1(0), IL2, 2019
… As a novel mechanism of ethanol- and diet-induced fatty liver, we report that downregulation of 3-phosphoglycerate dehydrogenase (PHGDH), a critical enzyme involved in the serine synthesis, and low hepatic serine level contribute to the development of fatty liver disease through suppressing SIRT1. …
NAID 130007677240